product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-Akt2 (Ser474) (D3H2) Rabbit mAb (Akt2 Specific)
catalog :
8599S
quantity :
100 ul
price :
291 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 5
Published Application/Species/DilutionReference
  • western blot; mouse; 1:500; fig 5
Jeffery E, Church C, Holtrup B, Colman L, Rodeheffer M. Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity. Nat Cell Biol. 2015;17:376-85 pubmed publisher
  • western blot; mouse; 1:1000; fig s9
Braccini L, Ciraolo E, Campa C, Perino A, Longo D, Tibolla G, et al. PI3K-C2γ is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling. Nat Commun. 2015;6:7400 pubmed publisher
  • western blot; mouse; fig 6a
Rao E, Zhang Y, Zhu G, Hao J, Persson X, Egilmez N, et al. Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death. Oncotarget. 2015;6:7944-58 pubmed
  • western blot; human
Vanli G, Peltzer N, Dubuis G, Widmann C. The activity of the anti-apoptotic fragment generated by the caspase-3/p120 RasGAP stress-sensing module displays strict Akt isoform specificity. Cell Signal. 2014;26:2992-7 pubmed publisher
Zhang W, Zhang X, Gonzalez-Cobos J, Stolwijk J, Matrougui K, Trebak M. Leukotriene-C4 synthase, a critical enzyme in the activation of store-independent Orai1/Orai3 channels, is required for neointimal hyperplasia. J Biol Chem. 2015;290:5015-27 pubmed publisher
product information
SKU :
8599S
Product-Name :
Phospho-Akt2 (Ser474) (D3H2) Rabbit mAb (Akt2 Specific)
Size :
100 ul
Price-(USD) :
291 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60
Host :
Rabbit
Target :
Akt2 (Ser474) phosphate
Primary-Protein :
Akt2
Alt-Names :
AKT2,Murine thymoma viral (v-akt) homolog-2,PKB beta,PKBB,PKBBETA,PRKBB,Protein kinase Akt-2,Protein kinase B beta,RAC-BETA,RAC-PK-beta,RAC-beta serine/threonine-protein kinase,rac protein kinase beta,v-akt murine thymoma viral oncogene homolog 2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.