product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cleaved Caspase-8 (Asp387) (D5B2) XP® Rabbit mAb (Mouse Specific)
catalog :
8592P
quantity :
40 ul
price :
135 USD
clonality :
monoclonal
host :
rabbit
reactivity :
mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
more info or order :
Cell Signaling Technology product webpage
citations: 10
Published Application/Species/DilutionReference
  • western blot; mouse; fig 3b
Kao S, Soares V, Kristiansen A, Stankovic K. Activation of TRAIL-DR5 pathway promotes sensorineural degeneration in the inner ear. Aging Cell. 2016;15:301-8 pubmed publisher
  • western blot; mouse; 1:100; fig 3
Huang Q, Perlman H, Birkett R, Doyle R, Fang D, Haines G, et al. CD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis. Nat Commun. 2015;6:7086 pubmed publisher
  • western blot; mouse; 1:200; fig 8
Nagata T, Yasukawa H, Kyogoku S, Oba T, Takahashi J, Nohara S, et al. Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules. PLoS ONE. 2015;10:e0127942 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500
  • immunoprecipitation; mouse; 1 ul
  • western blot; mouse; 1:500
Chi W, Chen H, Li F, Zhu Y, Yin W, Zhuo Y. HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma. J Neuroinflammation. 2015;12:137 pubmed publisher
  • western blot; mouse; fig 1
Antonucci L, Fagman J, Kim J, Todoric J, Gukovsky I, Mackey M, et al. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci U S A. 2015;112:E6166-74 pubmed publisher
  • western blot; mouse; fig s1
Wang X, Li Y, Liu S, Yu X, Li L, Shi C, et al. Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense. Proc Natl Acad Sci U S A. 2014;111:15438-43 pubmed publisher
  • western blot; mouse
Smithline Z, Nikonova A, Hensley H, Cai K, Egleston B, Proia D, et al. Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice. PLoS ONE. 2014;9:e114403 pubmed publisher
  • immunohistochemistry; rat; 1:10
Yurube T, Hirata H, Kakutani K, Maeno K, Takada T, Zhang Z, et al. Notochordal cell disappearance and modes of apoptotic cell death in a rat tail static compression-induced disc degeneration model. Arthritis Res Ther. 2014;16:R31 pubmed publisher
Gurung P, Anand P, Malireddi R, Vande Walle L, Van Opdenbosch N, Dillon C, et al. FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes. J Immunol. 2014;192:1835-46 pubmed publisher
McAllister C, Lakhdari O, Pineton de Chambrun G, Gareau M, Broquet A, Lee G, et al. TLR3, TRIF, and caspase 8 determine double-stranded RNA-induced epithelial cell death and survival in vivo. J Immunol. 2013;190:418-27 pubmed publisher
product information
SKU :
8592P
Product-Name :
Cleaved Caspase-8 (Asp387) (D5B2) XP® Rabbit mAb (Mouse Specific)
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
M
Applications :
Flow cytometry
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
18, 43
Host :
Rabbit
Target :
Casp8 (Asp387) cleaved mouse
Primary-Protein :
Casp8
Alt-Names :
CASP-8,Casp8,Caspase-8,Caspase-8 subunit p10,Caspase-8 subunit p18,FLICE,Fas-linked ICE-like protease,MACH,Mch5,caspase 8
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.