| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; loading ...; fig 3d
| Tanzer M, Khan N, Rickard J, Etemadi N, Lalaoui N, Spall S, et al. Combination of IAP antagonist and IFNγ activates novel caspase-10- and RIPK1-dependent cell death pathways. Cell Death Differ. 2017;24:481-491 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:600; loading ...; fig 1b
| Schünke H, Göbel U, Dikic I, Pasparakis M. OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice. Nat Commun. 2021;12:5912 pubmed publisher |
- western blot; mouse; loading ...; fig 3d
| Mandal P, Lyons J, Burd E, Koval M, Mocarski E, Coopersmith C. Integrated evaluation of lung disease in single animals. PLoS ONE. 2021;16:e0246270 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 2f
| Souza C, Ketelut Carneiro N, Milanezi C, Faccioli L, Gardinassi L, Silva J. NLRC4 inhibits NLRP3 inflammasome and abrogates effective antifungal CD8+ T cell responses. iScience. 2021;24:102548 pubmed publisher |
- western blot; mouse; loading ...; fig 2a
| Li X, Zhang M, Huang X, Liang W, Li G, Lu X, et al. Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners. Nat Commun. 2020;11:6364 pubmed publisher |
- western blot; human; loading ...; fig 4d
| Zhou X, Chen N, Xu H, Zhou X, Wang J, Fang X, et al. Regulation of Hippo-YAP signaling by insulin-like growth factor-1 receptor in the tumorigenesis of diffuse large B-cell lymphoma. J Hematol Oncol. 2020;13:77 pubmed publisher |
- western blot; human; loading ...; fig 3b
| Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, et al. Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells. Oncol Lett. 2019;18:3081-3091 pubmed publisher |
- western blot; mouse; loading ...; fig 5a
| Yuan Z, Zhang H, Hasnat M, Ding J, Chen X, Liang P, et al. A new perspective of triptolide-associated hepatotoxicity: Liver hypersensitivity upon LPS stimulation. Toxicology. 2019;414:45-56 pubmed publisher |
- western blot; mouse; fig s7a
| Li F, Li Y, Liang H, Xu T, Kong Y, Huang M, et al. HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection. J Clin Invest. 2018;128:4148-4162 pubmed publisher |
- western blot; human; loading ...; fig 2e
| Yang M, Li C, Zhu S, Cao L, Kroemer G, Zeh H, et al. TFAM is a novel mediator of immunogenic cancer cell death. Oncoimmunology. 2018;7:e1431086 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:800; loading ...; fig 4n
| Janečková E, Bíliková P, Matalova E. Osteogenic Potential of Caspases Related to Endochondral Ossification. J Histochem Cytochem. 2017;:22155417739283 pubmed publisher |
- western blot; mouse; loading ...; fig 2a
| Ogura H, Nagatake Kobayashi Y, Adachi J, Tomonaga T, Fujita N, Katayama R. TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity. Sci Rep. 2017;7:5519 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; loading ...; fig s6c
| Van T, Polykratis A, Straub B, Kondylis V, Papadopoulou N, Pasparakis M. Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J Clin Invest. 2017;127:2662-2677 pubmed publisher |
- western blot; mouse; 1:500; fig 2
| Pereira M, Tourlomousis P, Wright J, P Monie T, Bryant C. CARD9 negatively regulates NLRP3-induced IL-1? production on Salmonella infection of macrophages. Nat Commun. 2016;7:12874 pubmed publisher |
- western blot; mouse; fig 3b
| Kao S, Soares V, Kristiansen A, Stankovic K. Activation of TRAIL-DR5 pathway promotes sensorineural degeneration in the inner ear. Aging Cell. 2016;15:301-8 pubmed publisher |
- western blot; mouse; fig 1
| Antonucci L, Fagman J, Kim J, Todoric J, Gukovsky I, Mackey M, et al. Basal autophagy maintains pancreatic acinar cell homeostasis and protein synthesis and prevents ER stress. Proc Natl Acad Sci U S A. 2015;112:E6166-74 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:500
- immunoprecipitation; mouse; 1 ul
- western blot; mouse; 1:500
| Chi W, Chen H, Li F, Zhu Y, Yin W, Zhuo Y. HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma. J Neuroinflammation. 2015;12:137 pubmed publisher |
- western blot; mouse; loading ...; fig s2f
| Boutaffala L, Bertrand M, Remouchamps C, Seleznik G, Reisinger F, Janas M, et al. NIK promotes tissue destruction independently of the alternative NF-κB pathway through TNFR1/RIP1-induced apoptosis. Cell Death Differ. 2015;22:2020-33 pubmed publisher |
- western blot; mouse; 1:200; fig 8
| Nagata T, Yasukawa H, Kyogoku S, Oba T, Takahashi J, Nohara S, et al. Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules. PLoS ONE. 2015;10:e0127942 pubmed publisher |
- western blot; mouse; 1:100; fig 3
| Huang Q, Perlman H, Birkett R, Doyle R, Fang D, Haines G, et al. CD11c-mediated deletion of Flip promotes autoreactivity and inflammatory arthritis. Nat Commun. 2015;6:7086 pubmed publisher |
- western blot; human; 1:1000; fig 3
| Cheng H, Liang Y, Kuo Y, Chuu C, Lin C, Lee M, et al. Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death Dis. 2015;6:e1753 pubmed publisher |
- flow cytometry; mouse; fig 7
| Pei B, Zhao M, Miller B, Véla J, Bruinsma M, Virgin H, et al. Invariant NKT cells require autophagy to coordinate proliferation and survival signals during differentiation. J Immunol. 2015;194:5872-84 pubmed publisher |
| Smithline Z, Nikonova A, Hensley H, Cai K, Egleston B, Proia D, et al. Inhibiting heat shock protein 90 (HSP90) limits the formation of liver cysts induced by conditional deletion of Pkd1 in mice. PLoS ONE. 2014;9:e114403 pubmed publisher |
- western blot; mouse; fig s1
| Wang X, Li Y, Liu S, Yu X, Li L, Shi C, et al. Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense. Proc Natl Acad Sci U S A. 2014;111:15438-43 pubmed publisher |
- immunohistochemistry; mouse; 1:50
- western blot; mouse; 1:800
| Zheng H, Chen J, Sha S. Receptor-interacting protein kinases modulate noise-induced sensory hair cell death. Cell Death Dis. 2014;5:e1262 pubmed publisher |
- immunohistochemistry; rat; 1:10
| Yurube T, Hirata H, Kakutani K, Maeno K, Takada T, Zhang Z, et al. Notochordal cell disappearance and modes of apoptotic cell death in a rat tail static compression-induced disc degeneration model. Arthritis Res Ther. 2014;16:R31 pubmed publisher |
- immunocytochemistry; mouse; 1:400
| Tsuneki M, Madri J. CD44 regulation of endothelial cell proliferation and apoptosis via modulation of CD31 and VE-cadherin expression. J Biol Chem. 2014;289:5357-70 pubmed publisher |
- immunocytochemistry; mouse
- western blot; mouse
| Man S, Tourlomousis P, Hopkins L, Monie T, Fitzgerald K, Bryant C. Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1? production. J Immunol. 2013;191:5239-46 pubmed publisher |
| Komiya C, Tanaka M, Tsuchiya K, Shimazu N, Mori K, Furuke S, et al. Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis. Sci Rep. 2017;7:44754 pubmed publisher |
| Gurung P, Li B, Subbarao Malireddi R, Lamkanfi M, Geiger T, Kanneganti T. Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation. Sci Rep. 2015;5:14488 pubmed publisher |
| Gurung P, Anand P, Malireddi R, Vande Walle L, Van Opdenbosch N, Dillon C, et al. FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes. J Immunol. 2014;192:1835-46 pubmed publisher |
| McAllister C, Lakhdari O, Pineton de Chambrun G, Gareau M, Broquet A, Lee G, et al. TLR3, TRIF, and caspase 8 determine double-stranded RNA-induced epithelial cell death and survival in vivo. J Immunol. 2013;190:418-27 pubmed publisher |
