| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; fruit fly ; loading ...; fig 6l
| Zhou J, Xu L, Duan X, Liu W, Zhao X, Wang X, et al. Large-scale RNAi screen identified Dhpr as a regulator of mitochondrial morphology and tissue homeostasis. Sci Adv. 2019;5:eaax0365 pubmed publisher |
- western blot; rat; loading ...; fig 7a
| Qin W, Wu X, Jia Y, Tong X, Guo C, Chen D, et al. Suhuang antitussive capsule inhibits NLRP3 inflammasome activation and ameliorates pulmonary dysfunction via suppression of endoplasmic reticulum stress in cough variant asthma. Biomed Pharmacother. 2019;118:109188 pubmed publisher |
- western blot; human; loading ...; fig 4a, 8a
| Zheng J, Croteau D, Bohr V, Akbari M. Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells. Nucleic Acids Res. 2019;: pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5b
| Song C, Zhang J, Qi S, Liu Z, Zhang X, Zheng Y, et al. Cardiolipin remodeling by ALCAT1 links mitochondrial dysfunction to Parkinson's diseases. Aging Cell. 2019;18:e12941 pubmed publisher |
- western blot; human; 1:500; loading ...; fig 5e
| Yeshaw W, van der Zwaag M, Pinto F, Lahaye L, Faber A, Gómez Sánchez R, et al. Human VPS13A is associated with multiple organelles and influences mitochondrial morphology and lipid droplet motility. elife. 2019;8: pubmed publisher |
- western blot; mouse; loading ...; fig 2d
| Yan M, Ye L, Yin S, Lu X, Liu X, Lu S, et al. Glycycoumarin protects mice against acetaminophen-induced liver injury predominantly via activating sustained autophagy. Br J Pharmacol. 2018;175:3747-3757 pubmed publisher |
- western blot; rat; loading ...; fig 4a
| Chen Z, Li Y, Jiang G, Yang C, Wang Y, Wang X, et al. Knockdown of LRP6 activates Drp1 to inhibit survival of cardiomyocytes during glucose deprivation. Biomed Pharmacother. 2018;103:1408-1414 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s3e
| Dai S, Dulcey A, Hu X, Wassif C, Porter F, Austin C, et al. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy. 2017;13:1435-1451 pubmed publisher |
- western blot; rat; fig 1s2
| Monterisi S, Lobo M, Livie C, Castle J, Weinberger M, Baillie G, et al. PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling. elife. 2017;6: pubmed publisher |
- western blot; human; 1:500; loading ...; fig s7e
| Keckesova Z, Donaher J, De Cock J, Freinkman E, Lingrell S, Bachovchin D, et al. LACTB is a tumour suppressor that modulates lipid metabolism and cell state. Nature. 2017;543:681-686 pubmed publisher |
- immunocytochemistry; African green monkey; loading ...; fig 5a
- immunocytochemistry; mouse; loading ...; fig 4a
- western blot; mouse; loading ...; fig 3a
| Upadhyay M, Agarwal S, Bhadauriya P, Ganesh S. Loss of laforin or malin results in increased Drp1 level and concomitant mitochondrial fragmentation in Lafora disease mouse models. Neurobiol Dis. 2017;100:39-51 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig s5e
| Caino M, Seo J, Aguinaldo A, Wait E, Bryant K, Kossenkov A, et al. A neuronal network of mitochondrial dynamics regulates metastasis. Nat Commun. 2016;7:13730 pubmed publisher |
- western blot; human; fig 5
| Jung J, Ravi S, Lee D, McFadden K, Kamradt M, Toussaint L, et al. NIK/MAP3K14 Regulates Mitochondrial Dynamics and Trafficking to Promote Cell Invasion. Curr Biol. 2016;26:3288-3302 pubmed publisher |
- western blot; mouse; loading ...; fig 4a
| Barreto R, Mandili G, Witzmann F, Novelli F, Zimmers T, Bonetto A. Cancer and Chemotherapy Contribute to Muscle Loss by Activating Common Signaling Pathways. Front Physiol. 2016;7:472 pubmed |
- western blot; human; loading ...; fig 1d
| Zou P, Liu L, Zheng L, Payne K, Manjili M, Idowu M, et al. Coordinated Upregulation of Mitochondrial Biogenesis and Autophagy in Breast Cancer Cells: The Role of Dynamin Related Protein-1 and Implication for Breast Cancer Treatment. Oxid Med Cell Longev. 2016;2016:4085727 pubmed |
- western blot; human; loading ...; fig s1a
| Hatch A, Ji W, Merrill R, Strack S, Higgs H. Actin filaments as dynamic reservoirs for Drp1 recruitment. Mol Biol Cell. 2016;27:3109-3121 pubmed |
- western blot; mouse; fig 4
| El Sikhry H, Alsaleh N, Dakarapu R, Falck J, Seubert J. Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria. PLoS ONE. 2016;11:e0160380 pubmed publisher |
- western blot; mouse; 1:1000; fig 6
| Bal N, Maurya S, Singh S, Wehrens X, Periasamy M. Increased Reliance on Muscle-based Thermogenesis upon Acute Minimization of Brown Adipose Tissue Function. J Biol Chem. 2016;291:17247-57 pubmed publisher |
- western blot; human; fig s1
| Kobayashi K, Araya J, Minagawa S, Hara H, Saito N, Kadota T, et al. Involvement of PARK2-Mediated Mitophagy in Idiopathic Pulmonary Fibrosis Pathogenesis. J Immunol. 2016;197:504-16 pubmed publisher |
- western blot; mouse; fig 1
| Hall A, Burke N, Dongworth R, Kalkhoran S, Dyson A, Vicencio J, et al. Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction. Cell Death Dis. 2016;7:e2238 pubmed publisher |
- western blot; mouse; 1:1000; fig 4
| Kumari S, Mehta S, Milledge G, Huang X, Li H, Li P. Ubisol-Q10 Prevents Glutamate-Induced Cell Death by Blocking Mitochondrial Fragmentation and Permeability Transition Pore Opening. Int J Biol Sci. 2016;12:688-700 pubmed publisher |
- western blot; human; loading ...; fig 1d
| Swiader A, Nahapetyan H, Faccini J, D Angelo R, Mucher E, Elbaz M, et al. Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipids. Oncotarget. 2016;7:28821-35 pubmed publisher |
- western blot; mouse; 1:1000; fig 5b
| Prieto J, León M, Ponsoda X, Sendra R, Bort R, Ferrer Lorente R, et al. Early ERK1/2 activation promotes DRP1-dependent mitochondrial fission necessary for cell reprogramming. Nat Commun. 2016;7:11124 pubmed publisher |
- immunohistochemistry; rat; 1:200; fig 3
- western blot; rat; 1:1000; fig 3
| Viringipurampeer I, Metcalfe A, Bashar A, Sivak O, Yanai A, Mohammadi Z, et al. NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration. Hum Mol Genet. 2016;25:1501-16 pubmed publisher |
- western blot; mouse; fig 5
| Moriwaki K, Farias Luz N, Balaji S, De Rosa M, O Donnell C, Gough P, et al. The Mitochondrial Phosphatase PGAM5 Is Dispensable for Necroptosis but Promotes Inflammasome Activation in Macrophages. J Immunol. 2016;196:407-15 pubmed publisher |
- western blot; mouse; 1:1000; fig 6
| Leduc Gaudet J, Picard M, St Jean Pelletier F, Sgarioto N, Auger M, Vallée J, et al. Mitochondrial morphology is altered in atrophied skeletal muscle of aged mice. Oncotarget. 2015;6:17923-37 pubmed |
| Ailenberg M, Di Ciano Oliveira C, Szaszi K, Dan Q, Rozycki M, Kapus A, et al. Dynasore enhances the formation of mitochondrial antiviral signalling aggregates and endocytosis-independent NF-κB activation. Br J Pharmacol. 2015;172:3748-63 pubmed publisher |
| Ribeiro M, Rosenstock T, Oliveira A, Oliveira C, Rego A. Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington's disease knock-in striatal cells. Free Radic Biol Med. 2014;74:129-44 pubmed publisher |
| Ji W, Chakrabarti R, Fan X, Schoenfeld L, Strack S, Higgs H. Receptor-mediated Drp1 oligomerization on endoplasmic reticulum. J Cell Biol. 2017;216:4123-4139 pubmed publisher |
| Laker R, Drake J, Wilson R, Lira V, Lewellen B, Ryall K, et al. Ampk phosphorylation of Ulk1 is required for targeting of mitochondria to lysosomes in exercise-induced mitophagy. Nat Commun. 2017;8:548 pubmed publisher |
| Zhao Y, Chen Y, Miao G, Zhao H, Qu W, Li D, et al. The ER-Localized Transmembrane Protein EPG-3/VMP1 Regulates SERCA Activity to Control ER-Isolation Membrane Contacts for Autophagosome Formation. Mol Cell. 2017;67:974-989.e6 pubmed publisher |
| Perdiz D, Lorin S, Leroy Gori I, Poüs C. Stress-induced hyperacetylation of microtubule enhances mitochondrial fission and modulates the phosphorylation of Drp1 at 616Ser. Cell Signal. 2017;39:32-43 pubmed publisher |
| Vo M, Ko M, Lee U, Yoon E, Lee B, Cho W, et al. Developmentally regulated GTP-binding protein 2 depletion leads to mitochondrial dysfunction through downregulation of dynamin-related protein 1. Biochem Biophys Res Commun. 2017;486:1014-1020 pubmed publisher |
| Qiao A, Jin X, Pang J, Moskophidis D, Mivechi N. The transcriptional regulator of the chaperone response HSF1 controls hepatic bioenergetics and protein homeostasis. J Cell Biol. 2017;216:723-741 pubmed publisher |
| Li W, Reeb A, Lin B, Subramanian P, Fey E, Knoverek C, et al. Heat Shock-induced Phosphorylation of TAR DNA-binding Protein 43 (TDP-43) by MAPK/ERK Kinase Regulates TDP-43 Function. J Biol Chem. 2017;292:5089-5100 pubmed publisher |
| Xu L, Shen Y, Wang X, Wei L, Wang P, Yang H, et al. Mitochondrial dynamics changes with age in an APPsw/PS1dE9 mouse model of Alzheimer's disease. Neuroreport. 2017;28:222-228 pubmed publisher |
| Tang J, Hu Z, Tan J, Yang S, Zeng L. Parkin Protects against Oxygen-Glucose Deprivation/Reperfusion Insult by Promoting Drp1 Degradation. Oxid Med Cell Longev. 2016;2016:8474303 pubmed publisher |
| Gebhard A, Jain P, Nair R, Emmons M, Argilagos R, Koomen J, et al. MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma. Mol Cancer Ther. 2013;12:2446-58 pubmed publisher |
