product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-FAK (Tyr397) (D20B1) Rabbit mAb
catalog :
8556P
quantity :
40 ul
price :
123 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunoprecipitation
citations: 4
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; 1:1000; fig s4
  • western blot (knockdown validation); mouse; 1:1000; fig s4
Haemmerle M, Bottsford-Miller J, Pradeep S, Taylor M, Choi H, Hansen J, et al. FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. J Clin Invest. 2016;126:1885-96 pubmed publisher
  • western blot; human; 1:1000; tbl 1
Oudart J, Doué M, Vautrin A, Brassart B, Sellier C, Dupont-Deshorgue A, et al. The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction. Oncotarget. 2016;7:1516-28 pubmed publisher
  • western blot; human; 1:1000; fig 6
Kurozumi A, Goto Y, Matsushita R, Fukumoto I, Kato M, Nishikawa R, et al. Tumor-suppressive microRNA-223 inhibits cancer cell migration and invasion by targeting ITGA3/ITGB1 signaling in prostate cancer. Cancer Sci. 2016;107:84-94 pubmed publisher
  • immunohistochemistry; human; 1:100
Sallam A, Mohyeldin M, Foudah A, Akl M, Nazzal S, Meyer S, et al. Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling. Org Biomol Chem. 2014;12:5295-303 pubmed publisher
product information
SKU :
8556P
Product-Name :
Phospho-FAK (Tyr397) (D20B1) Rabbit mAb
Size :
40 ul
Price-(USD) :
123 USD
Species-x-Reactivity :
H, (M, R, Mk)
Applications :
Immunoprecipitation
Product-Category :
Adhesion/ECM
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
125
Host :
Rabbit
Target :
FAK (Tyr397) phosphate
Primary-Protein :
FAK
Alt-Names :
FADK,FADK 1,FAK,FAK-related non-kinase polypeptide,FAK1,FRNK,Focal adhesion kinase 1,PTK2,PTK2 protein tyrosine kinase 2,Protein-tyrosine kinase 2,pp125FAK
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.