| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig 4c
| Li P, Cao S, Huang Y, Zhang Y, Liu J, Cai X, et al. A novel chemical inhibitor suppresses breast cancer cell growth and metastasis through inhibiting HPIP oncoprotein. Cell Death Discov. 2021;7:198 pubmed publisher |
- western blot; human; 1:1000; fig 1n
| Yin H, Wang J, Li H, Yu Y, Wang X, Lu L, et al. Extracellular matrix protein-1 secretory isoform promotes ovarian cancer through increasing alternative mRNA splicing and stemness. Nat Commun. 2021;12:4230 pubmed publisher |
- western blot; human; loading ...; fig 6d
| Cheng X, Wang J, Liu C, Jiang T, Yang N, Liu D, et al. Zinc transporter SLC39A13/ZIP13 facilitates the metastasis of human ovarian cancer cells via activating Src/FAK signaling pathway. J Exp Clin Cancer Res. 2021;40:199 pubmed publisher |
- western blot; human; loading ...; fig 6a
| Zhu J, Cai T, Zhou J, Du W, Zeng Y, Liu T, et al. CD151 drives cancer progression depending on integrin α3β1 through EGFR signaling in non-small cell lung cancer. J Exp Clin Cancer Res. 2021;40:192 pubmed publisher |
- western blot; human; loading ...; fig 4c, 4h
| Qin X, Li J, Wang S, Lv J, Luan F, Liu Y, et al. Serotonin/HTR1E signaling blocks chronic stress-promoted progression of ovarian cancer. Theranostics. 2021;11:6950-6965 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 7g
| Huang Y, Liang C, Ritz D, Coelho R, Septiadi D, Estermann M, et al. Collagen-rich omentum is a premetastatic niche for integrin α2-mediated peritoneal metastasis. elife. 2020;9: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 6a
| Liu Y, Li L, Liu X, Wang Y, Liu L, Peng L, et al. Arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling. elife. 2020;9: pubmed publisher |
- immunocytochemistry; human; loading ...; fig 3d, 3f
- western blot; human; loading ...; fig 3a
| Rigiracciolo D, Nohata N, Lappano R, Cirillo F, Talia M, Scordamaglia D, et al. IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells. Cells. 2020;9: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 6d
| Yuan M, Xie F, Xia X, Zhong K, Lian L, Zhang S, et al. UNC5C‑knockdown enhances the growth and metastasis of breast cancer cells by potentiating the integrin α6/β4 signaling pathway. Int J Oncol. 2019;: pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2i, s5e
| Kuninty P, Bansal R, de Geus S, Mardhian D, Schnittert J, van Baarlen J, et al. ITGA5 inhibition in pancreatic stellate cells attenuates desmoplasia and potentiates efficacy of chemotherapy in pancreatic cancer. Sci Adv. 2019;5:eaax2770 pubmed publisher |
- western blot; human; loading ...; fig 3f
| Liu Y, Wang X, Deng L, Ping L, Shi Y, Zheng W, et al. ITK inhibition induced in vitro and in vivo anti-tumor activity through downregulating TCR signaling pathway in malignant T cell lymphoma. Cancer Cell Int. 2019;19:32 pubmed publisher |
- immunocytochemistry; mouse; 1:100; loading ...; fig s3d
| Mason D, Collins J, Dawahare J, Nguyen T, Lin Y, Voytik Harbin S, et al. YAP and TAZ limit cytoskeletal and focal adhesion maturation to enable persistent cell motility. J Cell Biol. 2019;218:1369-1389 pubmed publisher |
- western blot; human; loading ...; fig 5a
| de Jong O, van der Waals L, Kools F, Verhaar M, van Balkom B. Lysyl oxidase-like 2 is a regulator of angiogenesis through modulation of endothelial-to-mesenchymal transition. J Cell Physiol. 2019;234:10260-10269 pubmed publisher |
- western blot; human; fig 3c
| Emori T, Hirose J, Ise K, Yomoda J, Kasahara M, Shinkuma T, et al. Constitutive Activation of Integrin ?9 Augments Self-Directed Hyperplastic and Proinflammatory Properties of Fibroblast-like Synoviocytes of Rheumatoid Arthritis. J Immunol. 2017;199:3427-3436 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 7a1
| Shen C, Sun L, Zhu N, Qi F. Kindlin-1 contributes to EGF-induced re-epithelialization in skin wound healing. Int J Mol Med. 2017;39:949-959 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig ev3b
| Fallahi Sichani M, Becker V, Izar B, Baker G, Lin J, Boswell S, et al. Adaptive resistance of melanoma cells to RAF inhibition via reversible induction of a slowly dividing de-differentiated state. Mol Syst Biol. 2017;13:905 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3
| Wang Y, Chiang H, Huang Y, Hsu C, Yang P, Juan H, et al. A link between adipogenesis and innate immunity: RNase-L promotes 3T3-L1 adipogenesis by destabilizing Pref-1 mRNA. Cell Death Dis. 2016;7:e2458 pubmed publisher |
- western blot; human; loading ...; fig 8a
| Zhang C, Wang H, Bao Q, Wang L, Guo T, Chen W, et al. NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction. Oncotarget. 2016;7:73593-73606 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4f
| Cao R, Meng Z, Liu T, Wang G, Qian G, Cao T, et al. Decreased TRPM7 inhibits activities and induces apoptosis of bladder cancer cells via ERK1/2 pathway. Oncotarget. 2016;7:72941-72960 pubmed publisher |
- western blot; mouse; 1:1000; fig s7d
| Rozo M, Li L, Fan C. Targeting ?1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice. Nat Med. 2016;22:889-96 pubmed publisher |
- western blot; human; 1:1000; fig s6
- western blot; mouse; 1:1000; fig s4
| Haemmerle M, Bottsford Miller J, Pradeep S, Taylor M, Choi H, Hansen J, et al. FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. J Clin Invest. 2016;126:1885-96 pubmed publisher |
- western blot; human; 1:1000; fig 4
| Liu T, Fang Z, Wang G, Shi M, Wang X, Jiang K, et al. Anti-tumor activity of the TRPM8 inhibitor BCTC in prostate cancer DU145 cells. Oncol Lett. 2016;11:182-188 pubmed |
- western blot; mouse; 1:1000; fig 6
| Zhang Y, Fan J, Ho J, Hu T, Kneeland S, Fan X, et al. Crim1 regulates integrin signaling in murine lens development. Development. 2016;143:356-66 pubmed publisher |
- western blot; human; 1:1000; tbl 1
| Oudart J, Doué M, Vautrin A, Brassart B, Sellier C, Dupont Deshorgue A, et al. The anti-tumor NC1 domain of collagen XIX inhibits the FAK/ PI3K/Akt/mTOR signaling pathway through αvβ3 integrin interaction. Oncotarget. 2016;7:1516-28 pubmed publisher |
- western blot; human; 1:1000; fig 6
| Kurozumi A, Goto Y, Matsushita R, Fukumoto I, Kato M, Nishikawa R, et al. Tumor-suppressive microRNA-223 inhibits cancer cell migration and invasion by targeting ITGA3/ITGB1 signaling in prostate cancer. Cancer Sci. 2016;107:84-94 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 11
| Sugiyama S, Yoshino Y, Kuriyama S, Inoue M, Komine K, Otsuka K, et al. A Curcumin Analog, GO-Y078, Effectively Inhibits Angiogenesis through Actin Disorganization. Anticancer Agents Med Chem. 2016;16:633-47 pubmed |
- immunocytochemistry; mouse; fig 4
- western blot; mouse; fig 4
| Cáceres M, Ortiz L, Recabarren T, Romero A, Colombo A, Leiva Salcedo E, et al. TRPM4 Is a Novel Component of the Adhesome Required for Focal Adhesion Disassembly, Migration and Contractility. PLoS ONE. 2015;10:e0130540 pubmed publisher |
- immunohistochemistry; human; 1:100
| Sallam A, Mohyeldin M, Foudah A, Akl M, Nazzal S, Meyer S, et al. Marine natural products-inspired phenylmethylene hydantoins with potent in vitro and in vivo antitumor activities via suppression of Brk and FAK signaling. Org Biomol Chem. 2014;12:5295-303 pubmed publisher |
- western blot; human; 1:1000
| Elliott V, Rychahou P, Zaytseva Y, Evers B. Activation of c-Met and upregulation of CD44 expression are associated with the metastatic phenotype in the colorectal cancer liver metastasis model. PLoS ONE. 2014;9:e97432 pubmed publisher |
- immunocytochemistry; human
- western blot; human
| Dave J, Kang H, Abbey C, Maxwell S, Bayless K. Proteomic profiling of endothelial invasion revealed receptor for activated C kinase 1 (RACK1) complexed with vimentin to regulate focal adhesion kinase (FAK). J Biol Chem. 2013;288:30720-33 pubmed publisher |
| Ethaeb A, Mohammad M, Madkhali Y, Featherby S, Maraveyas A, Greenman J, et al. Accumulation of tissue factor in endothelial cells promotes cellular apoptosis through over-activation of Src1 and involves β1-integrin signalling. Apoptosis. 2020;25:29-41 pubmed publisher |
| Perri A, Agosti V, Olivo E, Concolino A, Angelis M, Tammè L, et al. Histone proteomics reveals novel post-translational modifications in breast cancer. Aging (Albany NY). 2019;11:11722-11755 pubmed publisher |
| Mohan A, Dean K, Isogai T, Kasitinon S, Murali V, Roudot P, et al. Enhanced Dendritic Actin Network Formation in Extended Lamellipodia Drives Proliferation in Growth-Challenged Rac1P29S Melanoma Cells. Dev Cell. 2019;49:444-460.e9 pubmed publisher |
| Vornhagen J, Armistead B, Santana Ufret V, Gendrin C, Merillat S, Coleman M, et al. Group B streptococcus exploits vaginal epithelial exfoliation for ascending infection. J Clin Invest. 2018;128:1985-1999 pubmed publisher |
| Cook J, Ueno N, Lodoen M. Toxoplasma gondii disrupts β1 integrin signaling and focal adhesion formation during monocyte hypermotility. J Biol Chem. 2018;293:3374-3385 pubmed publisher |
| Feng Y, Jin D, Sokol E, Reinhardt F, Miller D, Gupta P. Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1. Nat Commun. 2017;8:1079 pubmed publisher |
| Fan Y, Qu X, Ma Y, Liu Y, Hu X. Cbl-b promotes cell detachment via ubiquitination of focal adhesion kinase. Oncol Lett. 2016;12:1113-1118 pubmed |
| Kang W, Kim S, Cho H, Jin J, Lee J, Joo K, et al. Talin1 targeting potentiates anti-angiogenic therapy by attenuating invasion and stem-like features of glioblastoma multiforme. Oncotarget. 2015;6:27239-51 pubmed publisher |
| Zhuo B, Wang R, Zhang H, Qin H, Yin Y, Shi Y. Interleukin-24 inhibits cell migration and invasion in the neuroblastoma cell line SH-SY5Y. Oncol Rep. 2013;30:2749-54 pubmed publisher |
