Btk (D3H5) Rabbit mAb | Cell Signaling Technology 8547 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Btk (D3H5) Rabbit mAb

catalog :

8547

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D3H5

reactivity :

human, mouse, rat, dogs, bovine

application :

western blot, immunohistochemistry, immunoprecipitation, flow cytometry, mass cytometry

more info or order :

Cell Signaling Technology product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:200; loading ...; fig 1b	Zhao J, Chen J, Li Y, Xia L, Wu Y. Bruton's tyrosine kinase regulates macrophage‑induced inflammation in the diabetic kidney via NLRP3 inflammasome activation. Int J Mol Med. 2021;48: pubmed publisher
mass cytometry; human; 1:200; loading ...; fig s2	West J, Austin E, Rizzi E, Yan L, Tanjore H, Crabtree A, et al. KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models. Int J Mol Sci. 2021;22: pubmed publisher
western blot; human; 1:1000; loading ...; fig 3b, 3e	Thomsen E, Rovsing A, Anderson M, Due H, Huang J, Luo Y, et al. Identification of BLNK and BTK as mediators of rituximab-induced programmed cell death by CRISPR screens in GCB-subtype diffuse large B-cell lymphoma. Mol Oncol. 2020;: pubmed publisher
western blot; mouse; loading ...; fig s1a	Das S, Bar Sagi D. BTK signaling drives CD1dhiCD5+ regulatory B-cell differentiation to promote pancreatic carcinogenesis. Oncogene. 2019;38:3316-3324 pubmed publisher
western blot; human; loading ...; fig 5d	Burgess M, Mapp S, Mazzieri R, Cheung C, Chambers L, Mattarollo S, et al. Increased FcÎ³RIIB dominance contributes to the emergence of resistance to therapeutic antibodies in chronic lymphocytic leukaemia patients. Oncogene. 2017;36:2366-2376 pubmed publisher
western blot; human; fig 5b	Dai B, Chen A, Corkum C, Peroutka R, Landon A, Houng S, et al. Hepatitis C virus upregulates B-cell receptor signaling: a novel mechanism for HCV-associated B-cell lymphoproliferative disorders. Oncogene. 2016;35:2979-90 pubmed publisher
western blot; rat; fig 5	Bradshaw J, McFarland J, Paavilainen V, Bisconte A, Tam D, Phan V, et al. Prolonged and tunable residence time using reversible covalent kinase inhibitors. Nat Chem Biol. 2015;11:525-31 pubmed publisher
western blot; mouse; 1:1000; fig 8c	Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed publisher
	Mohr S, Doebele C, Comoglio F, Berg T, Beck J, Bohnenberger H, et al. Hoxa9 and Meis1 Cooperatively Induce Addiction to Syk Signaling by Suppressing miR-146a in Acute Myeloid Leukemia. Cancer Cell. 2017;31:549-562.e11 pubmed publisher
	Bonsignore L, Passelli K, Pelzer C, Perroud M, Konrad A, Thurau M, et al. A role for MALT1 activity in Kaposi's sarcoma-associated herpes virus latency and growth of primary effusion lymphoma. Leukemia. 2017;31:614-624 pubmed publisher
	Sharma N, Everingham S, Zeng L, Zhang Z, Kapur R, Craig A. Oncogenic KIT-induced aggressive systemic mastocytosis requires SHP2/PTPN11 phosphatase for disease progression in mice. Oncotarget. 2014;5:6130-41 pubmed
	Zheng X, Ding N, Song Y, Feng L, Zhu J. Different sensitivity of germinal center B cell-like diffuse large B cell lymphoma cells towards ibrutinib treatment. Cancer Cell Int. 2014;14:32 pubmed publisher

product information

SKU :

8547S

Product-Name :

Btk (D3H5) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, (R, Hm, Mk, B, Dg, Pg, Hr)

Applications :

Flow cytometry

Product-Category :

Immunology and Inflammation

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

BTK

Primary-Protein :

Btk

Alt-Names :

AGMX1,AT,ATK,Agammaglobulinaemia tyrosine kinase,B-cell progenitor kinase,BPK,BTK,Bruton agammaglobulinemia tyrosine kinase,Bruton tyrosine kinase,IMD1,MGC126261,MGC126262,PSCTK1,Tyrosine-protein kinase BTK,XLA,dominant-negative kinase-deficient Brutons tyrosine kinase

more info or order :

Cell Signaling Technology product webpage