product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
FLIP (D16A8) Rabbit mAb
catalog :
8510
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D16A8
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human
Yin Y, Zhang S, Luo H, Zhang X, Geng G, Li J, et al. Interleukin 7 up-regulates CD95 protein on CD4+ T cells by affecting mRNA alternative splicing: priming for a synergistic effect on HIV-1 reservoir maintenance. J Biol Chem. 2015;290:35-45 pubmed publisher
  • western blot; human
Bucur O, Pennarun B, Stancu A, Nadler M, Muraru M, Bertomeu T, et al. Poor antibody validation is a challenge in biomedical research: a case study for detection of c-FLIP. Apoptosis. 2013;18:1154-62 pubmed publisher
Fiore A, Ugel S, De Sanctis F, Sandri S, Fracasso G, Trovato R, et al. Induction of immunosuppressive functions and NF-κB by FLIP in monocytes. Nat Commun. 2018;9:5193 pubmed publisher
Lei F, Jin L, Liu X, Lai F, Yan X, Farrelly M, et al. RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors. Cell Death Dis. 2018;9:679 pubmed publisher
Feng L, Vujicic S, Dietrich M, Litbarg N, Setty S, Antoni A, et al. Repeated exposure of epithelial cells to apoptotic cells induces the specific selection of an adaptive phenotype: Implications for tumorigenesis. J Biol Chem. 2018;293:10245-10263 pubmed publisher
Guo X, Yin H, Chen Y, Li L, Li J, Liu Q. TAK1 regulates caspase 8 activation and necroptotic signaling via multiple cell death checkpoints. Cell Death Dis. 2016;7:e2381 pubmed publisher
van Roosmalen I, Reis C, Setroikromo R, Yuvaraj S, Joseph J, Tepper P, et al. The ER stress inducer DMC enhances TRAIL-induced apoptosis in glioblastoma. Springerplus. 2014;3:495 pubmed publisher
Hou Y, Liu L, Chai J, Yu Y, Duan H, Hu Q, et al. Lipopolysaccharide pretreatment inhibits LPS-induced human umbilical cord mesenchymal stem cell apoptosis via upregulating the expression of cellular FLICE-inhibitory protein. Mol Med Rep. 2015;12:2521-8 pubmed publisher
Qu L, He L, Zhao X, Xu W. Downregulation of miR-518a-3p activates the NIK-dependent NF-κB pathway in colorectal cancer. Int J Mol Med. 2015;35:1266-72 pubmed publisher
product information
SKU :
8510S
Product-Name :
FLIP (D16A8) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
55
Host :
Rabbit
Target :
FLIP
Primary-Protein :
CFLAR
Alt-Names :
CASH,CASP8 and FADD-like apoptosis regulator,CASP8 and FADD-like apoptosis regulator subunit p12,CASP8 and FADD-like apoptosis regulator subunit p43,CASP8AP1,CFLAR,CLARP,Caspase homolog,Caspase-eight-related protein,Caspase-like apoptosis regulatory protein,Casper,Cellular FLICE-like inhibitory protein,FADD-like anti-apoptotic molecule,FADD-like antiapoptotic molecule 1,FLAME,FLAME-1,FLAME1,FLIP,I-FLICE,Inhibitor of FLICE,MACH-related inducer of toxicity,MRIT,Usurpin,c-FLIP,c-FLIPL,c-FLIPR,c-FLIPS,caspase-related inducer of apoptosis,usurpin beta
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.