product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
USP10 (D7A5) Rabbit mAb
catalog :
8501
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D7A5
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; fig 3b
Wang W, Huang X, Xin H, Fu M, Xue A, Wu Z. TRAF Family Member-associated NF-κB Activator (TANK) Inhibits Genotoxic Nuclear Factor κB Activation by Facilitating Deubiquitinase USP10-dependent Deubiquitination of TRAF6 Ligase. J Biol Chem. 2015;290:13372-85 pubmed publisher
  • western blot; mouse; 1:3000; loading ...; fig 7d
  • western blot; human; 1:3000; loading ...; fig 7e
Guturi K, Bohgaki M, Bohgaki T, Srikumar T, Ng D, Kumareswaran R, et al. RNF168 and USP10 regulate topoisomerase II? function via opposing effects on its ubiquitylation. Nat Commun. 2016;7:12638 pubmed publisher
Carlino M, Fung C, Shahheydari H, Todd J, Boyd S, Irvine M, et al. Preexisting MEK1P124 mutations diminish response to BRAF inhibitors in metastatic melanoma patients. Clin Cancer Res. 2015;21:98-105 pubmed publisher
Katsila T, Juliachs M, Gregori J, Macarulla T, Villarreal L, Bardelli A, et al. Circulating pEGFR is a candidate response biomarker of cetuximab therapy in colorectal cancer. Clin Cancer Res. 2014;20:6346-56 pubmed publisher
Moreno Càceres J, Caja L, Mainez J, Mayoral R, Martin Sanz P, Moreno Vicente R, et al. Caveolin-1 is required for TGF-?-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17. Cell Death Dis. 2014;5:e1326 pubmed publisher
Fong J, Jacobs R, Moravec D, Uppada S, Botting G, Nlend M, et al. Alternative signaling pathways as potential therapeutic targets for overcoming EGFR and c-Met inhibitor resistance in non-small cell lung cancer. PLoS ONE. 2013;8:e78398 pubmed publisher
Asano R, Hagiwara Y, Koyama N, Masakari Y, Orimo R, Arai K, et al. Multimerization of anti-(epidermal growth factor receptor) IgG fragments induces an antitumor effect: the case for humanized 528 scFv multimers. FEBS J. 2013;280:4816-26 pubmed publisher
Paulson A, Linklater E, Berghuis B, App C, Oostendorp L, Paulson J, et al. MET and ERBB2 are coexpressed in ERBB2+ breast cancer and contribute to innate resistance. Mol Cancer Res. 2013;11:1112-21 pubmed publisher
Hall K, Hill D, Otero M, Plumb D, Froemel D, Dragomir C, et al. ADAM17 controls endochondral ossification by regulating terminal differentiation of chondrocytes. Mol Cell Biol. 2013;33:3077-90 pubmed publisher
Kuo H, Chen Y, Chang H, Jeng J, Lin E, Pan C, et al. The PML isoform IV is a negative regulator of nuclear EGFR's transcriptional activity in lung cancer. Carcinogenesis. 2013;34:1708-16 pubmed publisher
Xu B, Chen H, Xu W, Zhang W, Buckley S, Zheng S, et al. Molecular mechanisms of MMP9 overexpression and its role in emphysema pathogenesis of Smad3-deficient mice. Am J Physiol Lung Cell Mol Physiol. 2012;303:L89-96 pubmed publisher
Degen M, Natarajan E, Barron P, Widlund H, Rheinwald J. MAPK/ERK-dependent translation factor hyperactivation and dysregulated laminin ?2 expression in oral dysplasia and squamous cell carcinoma. Am J Pathol. 2012;180:2462-78 pubmed publisher
product information
SKU :
8501S
Product-Name :
USP10 (D7A5) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Ubiquitin and Ubiquitin-like proteins
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
110
Host :
Rabbit
Target :
USP10
Primary-Protein :
USP10
Alt-Names :
Deubiquitinating enzyme 10,KIAA0190,MGC2621,UBP10,UBPO,USP10,Ubiquitin carboxyl-terminal hydrolase 10,Ubiquitin thioesterase 10,Ubiquitin-specific-processing protease 10,ubiquitin specific peptidase 10,ubiquitin specific protease 10
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.