product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
p21 Waf1/Cip1 (12D1) Rabbit mAb (Alexa Fluor® 555 Conjugate)
catalog :
8493
clonality :
monoclonal
host :
rabbit
conjugate :
Alexa Fluor 555
clone name :
12D1
reactivity :
human
application :
immunocytochemistry
more info or order :
Cell Signaling Technology product webpage
citations: 15
Reference
Mohan M, Kumar V, Lackner A, Alvarez X. Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques. J Immunol. 2015;194:291-306 pubmed publisher
Hedbrant A, Erlandsson A, Delbro D, Wijkander J. Conditioned media from human macrophages of M1 phenotype attenuate the cytotoxic effect of 5‑fluorouracil on the HT‑29 colon cancer cell line. Int J Oncol. 2015;46:37-46 pubmed publisher
Narla A, Payne E, Abayasekara N, Hurst S, Raiser D, Look A, et al. L-Leucine improves the anaemia in models of Diamond Blackfan anaemia and the 5q- syndrome in a TP53-independent way. Br J Haematol. 2014;167:524-528 pubmed publisher
Zhang N, Ying M, Wu Y, Zhou Z, Ye Z, Li H, et al. Hyperoside, a flavonoid compound, inhibits proliferation and stimulates osteogenic differentiation of human osteosarcoma cells. PLoS ONE. 2014;9:e98973 pubmed publisher
Farooqi A, Dagg R, Choi L, Shay J, Reynolds C, Lau L. Alternative lengthening of telomeres in neuroblastoma cell lines is associated with a lack of MYCN genomic amplification and with p53 pathway aberrations. J Neurooncol. 2014;119:17-26 pubmed publisher
Al Moujahed A, Nicolaou F, Brodowska K, Papakostas T, Marmalidou A, Ksander B, et al. Uveal melanoma cell growth is inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase. Invest Ophthalmol Vis Sci. 2014;55:4175-85 pubmed publisher
Pesonen M, Häkkinen M, Rilla K, Juvonen R, Kuitunen T, Pasanen M, et al. Chloropicrin-induced toxic responses in human lung epithelial cells. Toxicol Lett. 2014;226:236-44 pubmed publisher
Ma T, Galimberti F, Erkmen C, Memoli V, Chinyengetere F, SEMPERE L, et al. Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancer. Mol Cancer Ther. 2013;12:1545-55 pubmed publisher
Rommer A, Steinmetz B, Herbst F, Hackl H, Heffeter P, Heilos D, et al. EVI1 inhibits apoptosis induced by antileukemic drugs via upregulation of CDKN1A/p21/WAF in human myeloid cells. PLoS ONE. 2013;8:e56308 pubmed publisher
Davis A, Cabello C, Qiao S, Azimian S, Wondrak G. Phenotypic identification of the redox dye methylene blue as an antagonist of heat shock response gene expression in metastatic melanoma cells. Int J Mol Sci. 2013;14:4185-202 pubmed publisher
Cardus A, Uryga A, Walters G, Erusalimsky J. SIRT6 protects human endothelial cells from DNA damage, telomere dysfunction, and senescence. Cardiovasc Res. 2013;97:571-9 pubmed publisher
Shum C, Lau S, Tsoi L, Chan L, Yam J, Ohira M, et al. Krüppel-like factor 4 (KLF4) suppresses neuroblastoma cell growth and determines non-tumorigenic lineage differentiation. Oncogene. 2013;32:4086-99 pubmed publisher
Li L, Cheng W, Li H, Li W, Yang H, Wen D, et al. Expression of proteasome activator REG? in human laryngeal carcinoma and associations with tumor suppressor proteins. Asian Pac J Cancer Prev. 2012;13:2699-703 pubmed
Morimoto Y, Takeuchi O, Takizawa A, Yoneyama H, Asanuma F, Suzuki Y, et al. Effect of a combination of S-1 and gemcitabine on cell cycle regulation in pancreatic cancer cell lines. Anticancer Drugs. 2012;23:505-14 pubmed publisher
Humphreys K, Cobiac L, Le Leu R, Van der Hoek M, Michael M. Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster. Mol Carcinog. 2013;52:459-74 pubmed publisher
product information
SKU :
8493S
Product-Name :
p21 Waf1/Cip1 (12D1) Rabbit mAb (Alexa Fluor® 555 Conjugate)
Size :
100 ul
Price-(USD) :
291 USD
Species-x-Reactivity :
H, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Cell Cycle / Checkpoint Control
Shipping-Temp :
COLD
Storage-Temp :
4°C
Product-Type :
Monoclonal Antibody
Host :
Rabbit
Target :
p21 Waf1/Cip1
Primary-Protein :
p21Cip1
Alt-Names :
CAP20,CDK-interacting protein 1,CDK-interaction protein 1,CDKN1,CDKN1A,CDN1A,CIP1,Cyclin-dependent kinase inhibitor 1,DNA synthesis inhibitor,MDA-6,MDA6,Melanoma differentiation-associated protein 6,PIC1,SDI1,WAF1,cyclin-dependent kinase inhibitor 1A (p21, Cip1),melanoma differentiation associated protein 6,p21,p21CIP1,p21Cip1/Waf1,wild-type p53-activated fragment 1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.