SirT1 (1F3) Mouse mAb | Cell Signaling Technology 8469 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

SirT1 (1F3) Mouse mAb

catalog :

8469

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1F3

reactivity :

hamsters, human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation, western blot knockout validation

more info or order :

Cell Signaling Technology product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; human; fig 1	He M, Yuan H, Tan B, Bai R, Kim H, Bae S, et al. SIRT1-mediated downregulation of p27Kip1 is essential for overcoming contact inhibition of Kaposi's sarcoma-associated herpesvirus transformed cells. Oncotarget. 2016;7:75698-75711 pubmed publisher
western blot; human; fig 3 western blot knockout validation; mouse; fig 3	Lahusen T, Deng C. SRT1720 induces lysosomal-dependent cell death of breast cancer cells. Mol Cancer Ther. 2015;14:183-92 pubmed publisher
western blot; mouse; loading ...; fig 4b	Dong W, Zhang H, Zhao C, Luo Y, Chen Y. Silencing of miR-150-5p Ameliorates Diabetic Nephropathy by Targeting SIRT1/p53/AMPK Pathway. Front Physiol. 2021;12:624989 pubmed publisher
western blot; mouse; 1:500; fig 5h	Affortit C, Casas F, Ladrech S, Ceccato J, Bourien J, Coyat C, et al. Exacerbated age-related hearing loss in mice lacking the p43 mitochondrial T3 receptor. BMC Biol. 2021;19:18 pubmed publisher
immunocytochemistry; human; loading ... western blot; human; loading ...; fig 1a, 1c	Meng F, Qian M, Peng B, Peng L, Wang X, Zheng K, et al. Synergy between SIRT1 and SIRT6 helps recognize DNA breaks and potentiates the DNA damage response and repair in humans and mice. elife. 2020;9: pubmed publisher
western blot; rat; 1:1000; loading ...; fig 4a	Zhang M, Du W, Acklin S, Jin S, Xia F. SIRT2 protects peripheral neurons from cisplatin-induced injury by enhancing nucleotide excision repair. J Clin Invest. 2020;130:2953-2965 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3c	Perri A, Agosti V, Olivo E, Concolino A, Angelis M, Tammè L, et al. Histone proteomics reveals novel post-translational modifications in breast cancer. Aging (Albany NY). 2019;11:11722-11755 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 6e	Li T, Song L, Sun Y, Li J, Yi C, Lam S, et al. Tip60-mediated lipin 1 acetylation and ER translocation determine triacylglycerol synthesis rate. Nat Commun. 2018;9:1916 pubmed publisher
western blot; human; loading ...; fig 3a	He M, Tan B, Vasan K, Yuan H, Cheng F, Ramos da Silva S, et al. SIRT1 and AMPK pathways are essential for the proliferation and survival of primary effusion lymphoma cells. J Pathol. 2017;242:309-321 pubmed publisher
western blot; human; loading ...; fig 7a	Yuan H, Tan B, Gao S. Tenovin-6 impairs autophagy by inhibiting autophagic flux. Cell Death Dis. 2017;8:e2608 pubmed publisher
western blot; mouse; loading ...; fig 4	Yang T, Wang J, Pang Y, Dang X, Ren H, Liu Y, et al. Emodin suppresses silica-induced lung fibrosis by promoting Sirt1 signaling via direct contact. Mol Med Rep. 2016;14:4643-4649 pubmed publisher
western blot; human; 1:1000; fig 1	Timucin A, Basaga H. SIRT6 Is a Positive Regulator of Aldose Reductase Expression in U937 and HeLa cells under Osmotic Stress: In Vitro and In Silico Insights. PLoS ONE. 2016;11:e0161494 pubmed publisher
western blot; human; 1:500; loading ...; fig 2	Wawrzyniak N, Joseph A, Levin D, Gundermann D, Leeuwenburgh C, Sandesara B, et al. Idiopathic chronic fatigue in older adults is linked to impaired mitochondrial content and biogenesis signaling in skeletal muscle. Oncotarget. 2016;7:52695-52709 pubmed publisher
western blot; rat; loading ...; fig 3a	Deng H, Mi M. Resveratrol Attenuates A?25-35 Caused Neurotoxicity by Inducing Autophagy Through the TyrRS-PARP1-SIRT1 Signaling Pathway. Neurochem Res. 2016;41:2367-79 pubmed publisher
immunocytochemistry; hamsters; 1:100 western blot; hamsters	Wang J, Zhang J, Shi Q, Zhang B, Chen C, Chen L, et al. Scrapie infection in experimental rodents and SMB-S15 cells decreased the brain endogenous levels and activities of Sirt1. J Mol Neurosci. 2015;55:1022-30 pubmed publisher
	Mendham A, Duffield R, Coutts A, Marino F, Boyko A, Bishop D. Rugby-specific small-sided games training is an effective alternative to stationary cycling at reducing clinical risk factors associated with the development of type 2 diabetes: a randomized, controlled trial. PLoS ONE. 2015;10:e0127548 pubmed publisher
	Castillo R, Zepeda A, Short S, Figueroa E, Bustos Obregon E, FarÃas J. Protective effects of polyunsatutared fatty acids supplementation against testicular damage induced by intermittent hypobaric hypoxia in rats. J Biomed Sci. 2015;22:8 pubmed publisher
	Li X, Fang E, Scheibye Knudsen M, Cui H, Qiu L, Li J, et al. Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis. Sci Rep. 2014;4:6434 pubmed publisher

product information

SKU :

8469S

Product-Name :

SirT1 (1F3) Mouse mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Immunofluorescence (Immunocytochemistry)

Product-Category :

Chromatin Regulation / Nuclear Function

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

120

Host :

Mouse

Target :

SirT1

Primary-Protein :

SIRT1

Alt-Names :

NAD-dependent deacetylase sirtuin-1,SIR2-like protein 1,SIR2L1,SIR2alpha,SIRT1,hSIR2,hSIRT1,sir2-like 1,sirtuin (silent mating type information regulation 2 homolog) 1 (S. cerevisiae),sirtuin 1,sirtuin type 1

more info or order :

Cell Signaling Technology product webpage