product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Rubicon (D9F7) Rabbit mAb
catalog :
8465
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D9F7
reactivity :
human, mouse, rat
application :
western blot, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 5f
  • western blot knockout validation; mouse; 1:1000; loading ...; fig s1e
Yamamuro T, Nakamura S, Yamano Y, Endo T, Yanagawa K, Tokumura A, et al. Rubicon prevents autophagic degradation of GATA4 to promote Sertoli cell function. PLoS Genet. 2021;17:e1009688 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4b
Yamamuro T, Kawabata T, Fukuhara A, Saita S, Nakamura S, Takeshita H, et al. Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. Nat Commun. 2020;11:4150 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s3k
Yamamoto K, Venida A, Yano J, Biancur D, Kakiuchi M, Gupta S, et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020;581:100-105 pubmed publisher
  • western blot; mouse; loading ...; fig 5a
Hartlova A, Herbst S, Peltier J, Rodgers A, Bilkei Gorzo O, Fearns A, et al. LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages. EMBO J. 2018;37: pubmed publisher
  • western blot; rat; loading ...; fig 2h
Bartolomeo R, Cinque L, De Leonibus C, Forrester A, Salzano A, Monfregola J, et al. mTORC1 hyperactivation arrests bone growth in lysosomal storage disorders by suppressing autophagy. J Clin Invest. 2017;127:3717-3729 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Nemazanyy I, Montagnac G, Russell R, Morzyglod L, Burnol A, Guan K, et al. Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. Nat Commun. 2015;6:8283 pubmed publisher
  • western blot; human; fig 5g
Munson M, Allen G, Toth R, Campbell D, Lucocq J, Ganley I. mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival. EMBO J. 2015;34:2272-90 pubmed publisher
product information
SKU :
8465S
Product-Name :
Rubicon (D9F7) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M
Applications :
Western blot
Product-Category :
Autophagy
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
130
Host :
Rabbit
Target :
RUBICON
Primary-Protein :
rubicon
Alt-Names :
K0226,KIAA0226,Uncharacterized protein KIAA0226,hypothetical protein LOC9711
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.