CYLD (D1A10) Rabbit mAb | Cell Signaling Technology 8462 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

CYLD (D1A10) Rabbit mAb

catalog :

8462

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D1A10

reactivity :

human, mouse, rat, dogs, bovine

application :

western blot, immunoprecipitation

more info or order :

Cell Signaling Technology product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:2000; loading ...; fig 5a	Wang Z, Feng J, Yu J, Chen G. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation. J Cell Sci. 2019;132: pubmed publisher
western blot; human; 1:1000; fig s15	Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed publisher
western blot; human; fig 5	Wagner S, Satpathy S, Beli P, Choudhary C. SPATA2 links CYLD to the TNF-? receptor signaling complex and modulates the receptor signaling outcomes. EMBO J. 2016;35:1868-84 pubmed publisher
western blot; human; 1:1000; fig s11	Lin W, Zhang J, Lin H, Li Z, Sun X, Xin D, et al. Syndecan-4 negatively regulates antiviral signalling by mediating RIG-I deubiquitination via CYLD. Nat Commun. 2016;7:11848 pubmed publisher
western blot; human	Monian P, Jiang X. The Cellular Apoptosis Susceptibility Protein (CAS) Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis and Cell Proliferation. J Biol Chem. 2016;291:2379-88 pubmed publisher
western blot; human; fig 3, 4, 5	Kobayashi T, Masoumi K, Massoumi R. Deubiquitinating activity of CYLD is impaired by SUMOylation in neuroblastoma cells. Oncogene. 2015;34:2251-60 pubmed publisher
western blot; human; 1:1000; fig 2b	Liang Q, Dexheimer T, Zhang P, Rosenthal A, Villamil M, You C, et al. A selective USP1-UAF1 inhibitor links deubiquitination to DNA damage responses. Nat Chem Biol. 2014;10:298-304 pubmed publisher
	Xu X, Kalac M, Markson M, Chan M, Brody J, Bhagat G, et al. Reversal of CYLD phosphorylation as a novel therapeutic approach for adult T-cell leukemia/lymphoma (ATLL). Cell Death Dis. 2020;11:94 pubmed publisher
	Kreckel J, Anany M, Siegmund D, Wajant H. TRAF2 Controls Death Receptor-Induced Caspase-8 Processing and Facilitates Proinflammatory Signaling. Front Immunol. 2019;10:2024 pubmed publisher
	Lee I, Lim J, Cho H, Kim E, Kim Y, Oh H, et al. MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity. Mol Cell. 2019;73:1138-1149.e6 pubmed publisher
	Guo X, Yin H, Chen Y, Li L, Li J, Liu Q. TAK1 regulates caspase 8 activation and necroptotic signaling via multiple cell death checkpoints. Cell Death Dis. 2016;7:e2381 pubmed publisher
	Xu D, Zhou P, Wang Y, Zhang L, Fu W, Ruan B, et al. Reciprocal activation between STAT3 and miR-181b regulates the proliferation of esophageal cancer stem-like cells via the CYLD pathway. Mol Cancer. 2016;15:40 pubmed publisher
	Klein T, Fung S, Renner F, Blank M, Dufour A, Kang S, et al. The paracaspase MALT1 cleaves HOIL1 reducing linear ubiquitination by LUBAC to dampen lymphocyte NF-ÎºB signalling. Nat Commun. 2015;6:8777 pubmed publisher
	Wu X, Fukushima H, North B, Nagaoka Y, Nagashima K, Deng F, et al. SCF?-TRCP regulates osteoclastogenesis via promoting CYLD ubiquitination. Oncotarget. 2014;5:4211-21 pubmed

product information

SKU :

8462S

Product-Name :

CYLD (D1A10) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk, (Hm, B, Dg, GP, Hr)

Applications :

Immunoprecipitation

Product-Category :

Ubiquitin and Ubiquitin-like proteins

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

108

Host :

Rabbit

Target :

CYLD

Primary-Protein :

CYLD

Alt-Names :

CDMT,CYLD,CYLD1,CYLDI,Deubiquitinating enzyme CYLD,EAC,FLJ20180,FLJ31664,FLJ78684,HSPC057,KIAA0849,MFT,MFT1,Probable ubiquitin carboxyl-terminal hydrolase CYLD,SBS,TEM,USPL2,Ubiquitin thioesterase CYLD,Ubiquitin-specific-processing protease CYLD,cylindromatosis (turban tumor syndrome),ubiquitin specific peptidase like 2,ubiquitin thiolesterase CYLD

more info or order :

Cell Signaling Technology product webpage