| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot knockout validation; mouse; 1:1000; loading ...; fig s1b
| Gu X, Wang D, Xu Z, Wang J, Guo L, Chai R, et al. Prevention of acquired sensorineural hearing loss in mice by in vivo Htra2 gene editing. Genome Biol. 2021;22:86 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 5c
| Kalogirou C, Linxweiler J, Schmucker P, Snaebjornsson M, Schmitz W, Wach S, et al. MiR-205-driven downregulation of cholesterol biosynthesis through SQLE-inhibition identifies therapeutic vulnerability in aggressive prostate cancer. Nat Commun. 2021;12:5066 pubmed publisher |
- western blot; mouse; loading ...; fig 1b
| Opoku E, TRAUGHBER C, Zhang D, Iacano A, Khan M, Han J, et al. Gasdermin D Mediates Inflammation-Induced Defects in Reverse Cholesterol Transport and Promotes Atherosclerosis. Front Cell Dev Biol. 2021;9:715211 pubmed publisher |
- western blot; mouse; fig 2c
| Xia Z, Xu J, Lu E, He W, Deng S, Gong A, et al. m6A mRNA Methylation Regulates Epithelial Innate Antimicrobial Defense Against Cryptosporidial Infection. Front Immunol. 2021;12:705232 pubmed publisher |
- western blot; human; loading ...; fig 1a
| Feng L, Chen M, Li Y, Li M, Hu S, Zhou B, et al. Sirt1 deacetylates and stabilizes p62 to promote hepato-carcinogenesis. Cell Death Dis. 2021;12:405 pubmed publisher |
- western blot; human; loading ...; fig 4a
| Wilson M, Reske J, Holladay J, Neupane S, Ngo J, Cuthrell N, et al. ARID1A Mutations Promote P300-Dependent Endometrial Invasion through Super-Enhancer Hyperacetylation. Cell Rep. 2020;33:108366 pubmed publisher |
- western blot; mouse; loading ...; fig 6d
| Sun Q, Chen J, Xu L, Kang J, Wu X, Ren Y, et al. MUTYH Deficiency Is Associated with Attenuated Pulmonary Fibrosis in a Bleomycin-Induced Model. Oxid Med Cell Longev. 2020;2020:4828256 pubmed publisher |
- western blot; human; loading ...; fig 3d
| Lomphithak T, Choksi S, Mutirangura A, Tohtong R, Tencomnao T, Usubuchi H, et al. Receptor-interacting protein kinase 1 is a key mediator in TLR3 ligand and Smac mimetic-induced cell death and suppresses TLR3 ligand-promoted invasion in cholangiocarcinoma. Cell Commun Signal. 2020;18:161 pubmed publisher |
- western blot; rat; loading ...; fig 3c
| Sarker M, Lee J, Lee D, Chun K, Jun H. Attenuation of diabetic kidney injury in DPP4-deficient rats; role of GLP-1 on the suppression of AGE formation by inducing glyoxalase 1. Aging (Albany NY). 2020;12:593-610 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 2k
| Cai H, Li J, Zhang Y, Liao Y, Zhu Y, Wang C, et al. LDHA Promotes Oral Squamous Cell Carcinoma Progression Through Facilitating Glycolysis and Epithelial-Mesenchymal Transition. Front Oncol. 2019;9:1446 pubmed publisher |
- western blot; human; 1:15,000; loading ...; fig 4c
| Riessland M, Kolisnyk B, Kim T, Cheng J, Ni J, Pearson J, et al. Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons. Cell Stem Cell. 2019;25:514-530.e8 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4a
| Li Y, Liang R, Zhang X, Wang J, Shan C, Liu S, et al. Copper Chaperone for Superoxide Dismutase Promotes Breast Cancer Cell Proliferation and Migration via ROS-Mediated MAPK/ERK Signaling. Front Pharmacol. 2019;10:356 pubmed publisher |
- western blot; human; loading ...; fig 1a
| Cadena C, Ahmad S, Xavier A, Willemsen J, Park S, Park J, et al. Ubiquitin-Dependent and -Independent Roles of E3 Ligase RIPLET in Innate Immunity. Cell. 2019;177:1187-1200.e16 pubmed publisher |
- western blot; human; loading ...; fig 2c
| SCHADE A, Oser M, Nicholson H, DeCaprio J. Cyclin D-CDK4 relieves cooperative repression of proliferation and cell cycle gene expression by DREAM and RB. Oncogene. 2019;38:4962-4976 pubmed publisher |
- western blot; mouse; loading ...; fig 1g
| Feng F, Wang Z, Li R, Wu Q, Gu C, Xu Y, et al. Citrus alkaline extracts prevent fibroblast senescence to ameliorate pulmonary fibrosis via activation of COX-2. Biomed Pharmacother. 2019;112:108669 pubmed publisher |
- western blot; mouse; loading ...; fig s1a
| Das S, Bar Sagi D. BTK signaling drives CD1dhiCD5+ regulatory B-cell differentiation to promote pancreatic carcinogenesis. Oncogene. 2019;38:3316-3324 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 6c
| Kim H, Mun Y, Lee K, Park Y, Park J, Park J, et al. T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells. Nat Commun. 2018;9:3630 pubmed publisher |
- western blot; human; fig 6
| Nozawa T, Minowa Nozawa A, Aikawa C, Nakagawa I. The STX6-VTI1B-VAMP3 complex facilitates xenophagy by regulating the fusion between recycling endosomes and autophagosomes. Autophagy. 2017;13:57-69 pubmed publisher |
| Andersen N, Srinivas S, Piñero G, Monje P. A rapid and versatile method for the isolation, purification and cryogenic storage of Schwann cells from adult rodent nerves. Sci Rep. 2016;6:31781 pubmed publisher |
- western blot; mouse; fig 3c
| Fusakio M, Willy J, Wang Y, Mirek E, Al Baghdadi R, Adams C, et al. Transcription factor ATF4 directs basal and stress-induced gene expression in the unfolded protein response and cholesterol metabolism in the liver. Mol Biol Cell. 2016;27:1536-51 pubmed publisher |
- western blot; human; 1:1000; fig 4
| Nim S, Jeon J, Corbi Verge C, Seo M, Ivarsson Y, Moffat J, et al. Pooled screening for antiproliferative inhibitors of protein-protein interactions. Nat Chem Biol. 2016;12:275-81 pubmed publisher |
- western blot; mouse; 1:1000; fig s3
| Yang Y, Wang L, Bell P, McMenamin D, He Z, White J, et al. A dual AAV system enables the Cas9-mediated correction of a metabolic liver disease in newborn mice. Nat Biotechnol. 2016;34:334-8 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 4h
| Yan L, Liu Y, Xiang J, Wu Q, Xu L, Luo X, et al. PIK3R1 targeting by miR-21 suppresses tumor cell migration and invasion by reducing PI3K/AKT signaling and reversing EMT, and predicts clinical outcome of breast cancer. Int J Oncol. 2016;48:471-84 pubmed publisher |
- western blot; mouse; fig 2
| Richardson E, Shukla S, Nagy N, Boom W, Beck R, Zhou L, et al. ERK Signaling Is Essential for Macrophage Development. PLoS ONE. 2015;10:e0140064 pubmed publisher |
- western blot; rat; 1:2500; fig 3
| Yan G, Wang Q, Hu S, Wang D, Qiao Y, Ma G, et al. Digoxin inhibits PDGF-BB-induced VSMC proliferation and migration through an increase in ILK signaling and attenuates neointima formation following carotid injury. Int J Mol Med. 2015;36:1001-11 pubmed publisher |
- western blot; mouse; 0.02 ug/ml; fig 4
| Cookman C, Belcher S. Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Growth of Medulloblastoma. Endocrinology. 2015;156:2395-408 pubmed publisher |
| Ma Y, Han W, Li J, Hu L, Zhou Y. Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic response in human colon cancer cells in vitro. Acta Pharmacol Sin. 2015;36:517-27 pubmed publisher |
- western blot; rat; fig 9f
| Xu J, Huang Z, Lin L, Fu M, Song Y, Shen Y, et al. miRNA-130b is required for the ERK/FOXM1 pathway activation-mediated protective effects of isosorbide dinitrate against mesenchymal stem cell senescence induced by high glucose. Int J Mol Med. 2015;35:59-71 pubmed publisher |
| Smith M, Tippetts T, Brassfield E, Tucker B, Ockey A, Swensen A, et al. Mitochondrial fission mediates ceramide-induced metabolic disruption in skeletal muscle. Biochem J. 2013;456:427-39 pubmed publisher |
| Pircher J, Czermak T, Ehrlich A, Eberle C, Gaitzsch E, Margraf A, et al. Cathelicidins prime platelets to mediate arterial thrombosis and tissue inflammation. Nat Commun. 2018;9:1523 pubmed publisher |
| Wang Y, Zhang X, Huang H, Xia Y, Yao Y, Mak A, et al. Osteocalcin expressing cells from tendon sheaths in mice contribute to tendon repair by activating Hedgehog signaling. elife. 2017;6: pubmed publisher |
| Wang Y, Zhang J, Su Y, Shen Y, Jiang D, Hou Y, et al. G9a regulates breast cancer growth by modulating iron homeostasis through the repression of ferroxidase hephaestin. Nat Commun. 2017;8:274 pubmed publisher |
| Mou H, Smith J, Peng L, Yin H, Moore J, Zhang X, et al. CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion. Genome Biol. 2017;18:108 pubmed publisher |
| Zhang Y, Xie L, Gunasekar S, Tong D, Mishra A, Gibson W, et al. SWELL1 is a regulator of adipocyte size, insulin signalling and glucose homeostasis. Nat Cell Biol. 2017;19:504-517 pubmed publisher |
| Karki R, Man S, Malireddi R, Kesavardhana S, Zhu Q, Burton A, et al. NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer. Nature. 2016;540:583-587 pubmed publisher |
| Zhang Y, Yu J, Lee C, Xu B, Sartor M, Koenig R. Genomic binding and regulation of gene expression by the thyroid carcinoma-associated PAX8-PPARG fusion protein. Oncotarget. 2015;6:40418-32 pubmed publisher |
| Hansen M, Simmons K, Tippetts T, Thatcher M, Saito R, Hubbard S, et al. Lipopolysaccharide Disrupts Mitochondrial Physiology in Skeletal Muscle via Disparate Effects on Sphingolipid Metabolism. Shock. 2015;44:585-92 pubmed publisher |
