product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
StAR (D10H12) XP® Rabbit mAb
catalog :
8449
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D10H12
reactivity :
human, mouse, rat, dogs
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 10
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 1c
Chi X, Luo W, Song J, Li B, Su T, Yu M, et al. Kindlin-2 in Sertoli cells is essential for testis development and male fertility in mice. Cell Death Dis. 2021;12:604 pubmed publisher
  • immunohistochemistry; human; 1:100; loading ...; fig 1b
Zhang C, Xie Y, Chen H, Lv L, Yao J, Zhang M, et al. FOXO4-DRI alleviates age-related testosterone secretion insufficiency by targeting senescent Leydig cells in aged mice. Aging (Albany NY). 2020;12:1272-1284 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 7c
  • western blot; mouse; loading ...; fig 7b
Wang X, Pan L, Zou Z, Wang D, Lu Y, Dong Z, et al. Hypoxia reduces testosterone synthesis in mouse Leydig cells by inhibiting NRF1-activated StAR expression. Oncotarget. 2017;8:16401-16413 pubmed publisher
  • western blot; dogs; loading ...; tbl 1
Bulldan A, Shihan M, Goericke Pesch S, Scheiner Bobis G. Signaling events associated with gonadotropin releasing hormone-agonist-induced hormonal castration and its reversal in canines. Mol Reprod Dev. 2016;83:1092-1101 pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 3
Ji X, Li Z, Chen H, Li J, Tian H, Li Z, et al. Cytotoxic mechanism related to dihydrolipoamide dehydrogenase in Leydig cells exposed to heavy metals. Toxicology. 2015;334:22-32 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 3
Lassance L, Haghiac M, Minium J, Catalano P, Hauguel De Mouzon S. Obesity-induced down-regulation of the mitochondrial translocator protein (TSPO) impairs placental steroid production. J Clin Endocrinol Metab. 2015;100:E11-8 pubmed publisher
  • western blot; mouse; 1:1000
Nteeba J, Ganesan S, Keating A. Progressive obesity alters ovarian folliculogenesis with impacts on pro-inflammatory and steroidogenic signaling in female mice. Biol Reprod. 2014;91:86 pubmed publisher
Karna K, Choi B, You J, Shin Y, Cui W, Lee S, et al. The ameliorative effect of monotropein, astragalin, and spiraeoside on oxidative stress, endoplasmic reticulum stress, and mitochondrial signaling pathway in varicocelized rats. BMC Complement Altern Med. 2019;19:333 pubmed publisher
Lee Thacker S, Choi Y, Taniuchi I, Takarada T, Yoneda Y, Ko C, et al. Core Binding Factor β Expression in Ovarian Granulosa Cells Is Essential for Female Fertility. Endocrinology. 2018;159:2094-2109 pubmed publisher
Li Y, He X, Yang X, Huang K, Luo Y, Zhu L, et al. Zinc inhibits the reproductive toxicity of Zearalenone in immortalized murine ovarian granular KK-1 cells. Sci Rep. 2015;5:14277 pubmed publisher
product information
SKU :
8449P
Product-Name :
StAR (D10H12) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
28
Host :
Rabbit
Target :
StAR
Primary-Protein :
StAR
Alt-Names :
STAR,STARD1,START domain containing 1,START domain-containing protein 1,StAR-related lipid transfer (START) domain containing 1,Steroidogenic acute regulatory protein, mitochondrial,cholesterol trafficker,mitochondrial steroid acute regulatory protein,steroid acute regulatory protein,steroidogenic acute regulator,steroidogenic acute regulatory protein
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.