product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cleaved Caspase-7 (Asp198) (D6H1) Rabbit mAb
catalog :
8438
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D6H1
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, flow cytometry
citations: 19
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...
Ye Z, Xu S, Shi Y, Bacolla A, Syed A, Moiani D, et al. GRB2 enforces homology-directed repair initiation by MRE11. Sci Adv. 2021;7: pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4b
Wang Y, Lan Y, Lu H. Opsin3 Downregulation Induces Apoptosis of Human Epidermal Melanocytes via Mitochondrial Pathway. Photochem Photobiol. 2020;96:83-93 pubmed publisher
  • western blot; mouse; loading ...; fig s1g
Fiore A, Ugel S, De Sanctis F, Sandri S, Fracasso G, Trovato R, et al. Induction of immunosuppressive functions and NF-κB by FLIP in monocytes. Nat Commun. 2018;9:5193 pubmed publisher
  • western blot; mouse; loading ...; fig 2a
Zhang X, Zhuang R, Wu H, Chen J, Wang F, Li G, et al. A novel role of endocan in alleviating LPS-induced acute lung injury. Life Sci. 2018;202:89-97 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5e
Yue X, Zuo Y, Ke H, Luo J, Lou L, Qin W, et al. Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase. Biochem Pharmacol. 2017;137:29-50 pubmed publisher
  • western blot; rat; 1:200; loading ...; fig 2d
Chambers T, Santiesteban L, Gomez D, Chambers J. Sab mediates mitochondrial dysfunction involved in imatinib mesylate-induced cardiotoxicity. Toxicology. 2017;382:24-35 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6c
Zhu Z, Tran H, Mathahs M, Moninger T, Schmidt W. HCV Induces Telomerase Reverse Transcriptase, Increases Its Catalytic Activity, and Promotes Caspase Degradation in Infected Human Hepatocytes. PLoS ONE. 2017;12:e0166853 pubmed publisher
  • western blot; human; loading ...; fig 6a
Liu H, Li W, Yu X, Gao F, Duan Z, Ma X, et al. EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis. Oncotarget. 2016;7:56338-56354 pubmed publisher
  • immunohistochemistry; mouse; 1:400; fig s6b
Yang D, Yuan Q, Balakrishnan A, Bantel H, Klusmann J, Manns M, et al. MicroRNA-125b-5p mimic inhibits acute liver failure. Nat Commun. 2016;7:11916 pubmed publisher
  • western blot; human; fig 2
Chaudhary S, Madhukrishna B, Adhya A, Keshari S, Mishra S. Overexpression of caspase 7 is ER? dependent to affect proliferation and cell growth in breast cancer cells by targeting p21(Cip). Oncogenesis. 2016;5:e219 pubmed publisher
  • western blot; human; fig 6
Spiesberger K, Paulfranz F, Egger A, Reiser J, Vogl C, Rudolf Scholik J, et al. Large-Scale Purification of r28M: A Bispecific scFv Antibody Targeting Human Melanoma Produced in Transgenic Cattle. PLoS ONE. 2015;10:e0140471 pubmed publisher
  • western blot; human; 1:200; fig 4b
Krossa S, Schmitt A, Hattermann K, Fritsch J, Scheidig A, Mehdorn H, et al. Down regulation of Akirin-2 increases chemosensitivity in human glioblastomas more efficiently than Twist-1. Oncotarget. 2015;6:21029-45 pubmed
  • western blot; mouse; fig 5
Gao Z, Zhang J, Henagan T, Lee J, Ye X, Wang H, et al. P65 inactivation in adipocytes and macrophages attenuates adipose inflammatory response in lean but not in obese mice. Am J Physiol Endocrinol Metab. 2015;308:E496-505 pubmed publisher
Agabiti S, Li J, Wiemer A. Geranylgeranyl diphosphate synthase inhibition induces apoptosis that is dependent upon GGPP depletion, ERK phosphorylation and caspase activation. Cell Death Dis. 2017;8:e2678 pubmed publisher
Vaklavas C, Grizzle W, Choi H, Meng Z, Zinn K, Shrestha K, et al. IRES inhibition induces terminal differentiation and synchronized death in triple-negative breast cancer and glioblastoma cells. Tumour Biol. 2016;37:13247-13264 pubmed
Wennmann D, Vollenbröker B, Eckart A, Bonse J, Erdmann F, Wolters D, et al. The Hippo pathway is controlled by Angiotensin II signaling and its reactivation induces apoptosis in podocytes. Cell Death Dis. 2014;5:e1519 pubmed publisher
Chang H, Wang H, Chen C, Hung T, Hou M, Yuan S, et al. 5-azacytidine induces anoikis, inhibits mammosphere formation and reduces metalloproteinase 9 activity in MCF-7 human breast cancer cells. Molecules. 2014;19:3149-59 pubmed publisher
Uppada S, Erickson T, Wojdyla L, Moravec D, Song Z, Cheng J, et al. Novel delivery system for T-oligo using a nanocomplex formed with an alpha helical peptide for melanoma therapy. Int J Nanomedicine. 2014;9:43-53 pubmed publisher
Pitman R, Wojdyla L, Puri N. Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma. Oncotarget. 2013;4:761-71 pubmed
product information
SKU :
8438S
Product-Name :
Cleaved Caspase-7 (Asp198) (D6H1) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, R, (Mk)
Applications :
Flow cytometry
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
18
Host :
Rabbit
Target :
Casp7 (Asp198, 20kD) cleaved
Primary-Protein :
Casp7
Alt-Names :
Apoptotic protease Mch-3,CASP-7,CASP7,CMH-1,Caspase-7,Caspase-7 subunit p11,Caspase-7 subunit p20,ICE-LAP3,ICE-like apoptotic protease 3,Lice2 alpha/beta/gamma,MCH3,caspase 7 isoform delta,caspase 7, apoptosis-related cysteine peptidase,caspase 7, apoptosis-related cysteine protease
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.