| Published Application/Species/Dilution | Reference |
|---|
- western blot; mouse; 1:1000; fig 5
| Acharya M, Sokolovska A, Tam J, Conway K, Stefani C, Raso F, et al. αv Integrins combine with LC3 and atg5 to regulate Toll-like receptor signalling in B cells. Nat Commun. 2016;7:10917 pubmed publisher |
- western blot; mouse; 1:1000; fig 1
| Uto T, Fukaya T, Takagi H, Arimura K, Nakamura T, Kojima N, et al. Clec4A4 is a regulatory receptor for dendritic cells that impairs inflammation and T-cell immunity. Nat Commun. 2016;7:11273 pubmed publisher |
- chromatin immunoprecipitation; mouse; 1:120; fig 6
| Kobayashi E, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, et al. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription. Nat Commun. 2016;7:11624 pubmed publisher |
- western blot; mouse; fig 4b
| Ramasamy S, Saez B, Mukhopadhyay S, Ding D, Ahmed A, Chen X, et al. Tle1 tumor suppressor negatively regulates inflammation in vivo and modulates NF-κB inflammatory pathway. Proc Natl Acad Sci U S A. 2016;113:1871-6 pubmed publisher |
- western blot; rat; 1:1000; fig 5
| Xu W, Huang M, Zhang Y, Li H, Zheng H, Yu L, et al. Extracts of Bauhinia championii (Benth.) Benth. attenuate the inflammatory response in a rat model of collagen-induced arthritis. Mol Med Rep. 2016;13:4167-74 pubmed publisher |
- western blot; human; 1:1000; fig 3
| Lu Z, Chen W, Li Y, Li L, Zhang H, Pang Y, et al. TNF-α enhances vascular cell adhesion molecule-1 expression in human bone marrow mesenchymal stem cells via the NF-κB, ERK and JNK signaling pathways. Mol Med Rep. 2016;14:643-8 pubmed publisher |
- western blot; human; 1:1000; fig s15
| Nakazawa S, Oikawa D, Ishii R, Ayaki T, Takahashi H, Takeda H, et al. Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis. Nat Commun. 2016;7:12547 pubmed publisher |
- western blot; rat; 1:2000
| Wang Y, Li J, Ji G, Zhai K, Wang H, Liu X. The Involvement of Ca(2+) Signal Pathways in Distal Colonic Myocytes in a Rat Model of Dextran Sulfate Sodium-induced Colitis. Chin Med J (Engl). 2016;129:1185-1192 pubmed publisher |
- western blot; mouse; fig 6
| Damgaard R, Walker J, Marco-Casanova P, Morgan N, Titheradge H, Elliott P, et al. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. Cell. 2016;166:1215-1230.e20 pubmed publisher |
- western blot; human; fig 6
| Huang L, Stuart C, Takeda K, D'AGNILLO F, Golding B. Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5. PLoS ONE. 2016;11:e0160875 pubmed publisher |
- western blot; mouse; 1:500; fig 4
| Chen G, Luo Y, Eriksson D, Meng X, Qian C, Bauerle T, et al. High fat diet increases melanoma cell growth in the bone marrow by inducing osteopontin and interleukin 6. Oncotarget. 2016;: pubmed publisher |
- western blot; mouse; 1:1000; fig 3
- immunocytochemistry; mouse; 1:200; fig 3
| Kishi N, MacDonald J, Ye J, Molyneaux B, Azim E, Macklis J. Reduction of aberrant NF-κB signalling ameliorates Rett syndrome phenotypes in Mecp2-null mice. Nat Commun. 2016;7:10520 pubmed publisher |
- western blot; mouse; fig 4
| Ahmad F, Chung Y, Tang Y, Hockman S, Liu S, Khan Y, et al. Phosphodiesterase 3B (PDE3B) regulates NLRP3 inflammasome in adipose tissue. Sci Rep. 2016;6:28056 pubmed publisher |
- western blot; mouse; 1:1000; fig 3
| Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher |
- western blot; mouse; fig 5
| Gao Q, Liu Y, Wu Y, Zhao Q, Wang L, Gao S, et al. IL-17 intensifies IFN-γ-induced NOS2 upregulation in RAW 264.7 cells by further activating STAT1 and NF-κB. Int J Mol Med. 2016;37:347-58 pubmed publisher |
- flow cytometry; mouse; fig 6
| Jin X, Yao T, Zhou Z, Zhu J, Zhang S, Hu W, et al. Advanced Glycation End Products Enhance Macrophages Polarization into M1 Phenotype through Activating RAGE/NF-κB Pathway. Biomed Res Int. 2015;2015:732450 pubmed publisher |
| Willy J, Young S, Stevens J, Masuoka H, Wek R. CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis. Mol Biol Cell. 2015;26:2190-204 pubmed publisher |
- western blot; human; fig 4
| Lee J, Park K, Han D, Bang N, Kim D, Na H, et al. PharmDB-K: Integrated Bio-Pharmacological Network Database for Traditional Korean Medicine. PLoS ONE. 2015;10:e0142624 pubmed publisher |
- western blot; mouse; 1:1000; fig 5
| Lin A, Jahrling J, Zhang W, Derosa N, Bakshi V, Romero P, et al. Rapamycin rescues vascular, metabolic and learning deficits in apolipoprotein E4 transgenic mice with pre-symptomatic Alzheimer's disease. J Cereb Blood Flow Metab. 2015;: pubmed |
- immunocytochemistry; mouse
| Leinenga G, Götz J. Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer's disease mouse model. Sci Transl Med. 2015;7:278ra33 pubmed publisher |
- western blot; human; 1:1000; fig 3
- immunocytochemistry; mouse; 1:100; fig s1
| Riesenberg S, Groetchen A, Siddaway R, Bald T, Reinhardt J, Smorra D, et al. MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment. Nat Commun. 2015;6:8755 pubmed publisher |
- western blot; human; 1:200; fig s5
- western blot; mouse; 1:200; fig s4
| Chen W, Wu J, Li L, Zhang Z, Ren J, Liang Y, et al. Ppm1b negatively regulates necroptosis through dephosphorylating Rip3. Nat Cell Biol. 2015;17:434-44 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:400; fig s4
| Binder Gallimidi A, Fischman S, Revach B, Bulvik R, Maliutina A, Rubinstein A, et al. Periodontal pathogens Porphyromonas gingivalis and Fusobacterium nucleatum promote tumor progression in an oral-specific chemical carcinogenesis model. Oncotarget. 2015;6:22613-23 pubmed |
| Kitai Y, Takeuchi O, Kawasaki T, Ori D, Sueyoshi T, Murase M, et al. Negative regulation of melanoma differentiation-associated gene 5 (MDA5)-dependent antiviral innate immune responses by Arf-like protein 5B. J Biol Chem. 2015;290:1269-80 pubmed publisher |
- immunohistochemistry - free floating section; human; 1:1000
| López-González I, Schluter A, Aso E, Garcia-Esparcia P, Ansoleaga B, Llorens F, et al. Neuroinflammatory signals in Alzheimer disease and APP/PS1 transgenic mice: correlations with plaques, tangles, and oligomeric species. J Neuropathol Exp Neurol. 2015;74:319-44 pubmed publisher |
| Greenfeld H, Takasaki K, Walsh M, Ersing I, Bernhardt K, Ma Y, et al. TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation. PLoS Pathog. 2015;11:e1004890 pubmed publisher |
- western blot; human; fig 2
| Yan S, Xu Z, Lou F, Zhang L, Ke F, Bai J, et al. NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis. Nat Commun. 2015;6:7652 pubmed publisher |
- western blot; human; fig s10d
| Shain A, Garrido M, Botton T, Talevich E, Yeh I, Sanborn J, et al. Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway. Nat Genet. 2015;47:1194-9 pubmed publisher |
| Alvaro-Bartolomé M, Garcia-Sevilla J. The neuroplastic index p-FADD/FADD and phosphoprotein PEA-15, interacting at GABAA receptor, are upregulated in brain cortex during midazolam-induced hypnosis in mice. Eur Neuropsychopharmacol. 2015;25:2131-44 pubmed publisher |
- western blot; rat; 1:1000
| Tang H, Hua F, Wang J, Yousuf S, Atif F, Sayeed I, et al. Progesterone and vitamin D combination therapy modulates inflammatory response after traumatic brain injury. Brain Inj. 2015;:1-10 pubmed |
- western blot; human; fig 3
- western blot; mouse; fig 3
| Fei F, Joo E, Tarighat S, Schiffer I, Paz H, Fabbri M, et al. B-cell precursor acute lymphoblastic leukemia and stromal cells communicate through Galectin-3. Oncotarget. 2015;6:11378-94 pubmed |
| Keller B, Garcia-Sevilla J. Regulation of hippocampal Fas receptor and death-inducing signaling complex after kainic acid treatment in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2015;63:54-62 pubmed publisher |
| Qu D, Weygant N, May R, Chandrakesan P, Madhoun M, Ali N, et al. Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis. PLoS ONE. 2015;10:e0134212 pubmed publisher |
| Nakahara T, Tanaka K, Ohno S, Egawa N, Yugawa T, Kiyono T. Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1. J Virol. 2015;89:5040-59 pubmed publisher |
- western blot; human; fig 2
| Ohashi M, Holthaus A, Calderwood M, Lai C, Krastins B, Sarracino D, et al. The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth. PLoS Pathog. 2015;11:e1004822 pubmed publisher |
| Singel S, Batten K, Cornelius C, Jia G, Fasciani G, Barron S, et al. Receptor-interacting protein kinase 2 promotes triple-negative breast cancer cell migration and invasion via activation of nuclear factor-kappaB and c-Jun N-terminal kinase pathways. Breast Cancer Res. 2014;16:R28 pubmed publisher |
- immunoprecipitation; human
- western blot; human
| Ma L, Pan Q, Sun F, Yu Y, Wang J. Cluster of differentiation 166 (CD166) regulates cluster of differentiation (CD44) via NF-κB in liver cancer cell line Bel-7402. Biochem Biophys Res Commun. 2014;451:334-8 pubmed publisher |
| Ballak D, van Essen P, van Diepen J, Jansen H, Hijmans A, Matsuguchi T, et al. MAP3K8 (TPL2/COT) affects obesity-induced adipose tissue inflammation without systemic effects in humans and in mice. PLoS ONE. 2014;9:e89615 pubmed publisher |
| Zhuang C, Sheng C, Shin W, Wu Y, Li J, Yao J, et al. A novel drug discovery strategy: mechanistic investigation of an enantiomeric antitumor agent targeting dual p53 and NF-κB pathways. Oncotarget. 2014;5:10830-9 pubmed |
| Kuwahara M, Suzuki J, Tofukuji S, Yamada T, Kanoh M, Matsumoto A, et al. The Menin-Bach2 axis is critical for regulating CD4 T-cell senescence and cytokine homeostasis. Nat Commun. 2014;5:3555 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
- western blot; mouse
| He X, Pu G, Tang R, Zhang D, Pan W. Activation of nuclear factor kappa B in the hepatic stellate cells of mice with schistosomiasis japonica. PLoS ONE. 2014;9:e104323 pubmed publisher |
| Liu B, Cao Y, Huizinga T, Hafler D, Toes R. TLR-mediated STAT3 and ERK activation controls IL-10 secretion by human B cells. Eur J Immunol. 2014;44:2121-9 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:200; fig 5c
| Henze A, Garvalov B, Seidel S, Cuesta A, Ritter M, Filatova A, et al. Loss of PHD3 allows tumours to overcome hypoxic growth inhibition and sustain proliferation through EGFR. Nat Commun. 2014;5:5582 pubmed publisher |
- immunocytochemistry; human; 1:50
| Dou W, Zhang J, Ren G, Ding L, Sun A, Deng C, et al. Mangiferin attenuates the symptoms of dextran sulfate sodium-induced colitis in mice via NF-κB and MAPK signaling inactivation. Int Immunopharmacol. 2014;23:170-8 pubmed publisher |
- chromatin immunoprecipitation; mouse
- western blot; mouse
| Day R, Cavaglieri R, Feliers D. Apelin retards the progression of diabetic nephropathy. Am J Physiol Renal Physiol. 2013;304:F788-800 pubmed publisher |
| Nagaraja A, Dorniak P, Sadaoui N, Kang Y, Lin T, Armaiz-Pena G, et al. Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis. Oncogene. 2016;35:2390-7 pubmed publisher |
| Yan X, Cen Y, Wang Q. Mesenchymal stem cells alleviate experimental rheumatoid arthritis through microRNA-regulated IκB expression. Sci Rep. 2016;6:28915 pubmed publisher |
| Wang S, Geng Z, Shi N, Li X, Wang Z. Dose-dependent effects of selenite (Se(4+)) on arsenite (As(3+))-induced apoptosis and differentiation in acute promyelocytic leukemia cells. Cell Death Dis. 2015;6:e1596 pubmed publisher |
| Guina T, Deiana M, Calfapietra S, Cabboi B, Maina M, Tuberoso C, et al. The role of p38 MAPK in the induction of intestinal inflammation by dietary oxysterols: modulation by wine phenolics. Food Funct. 2015;6:1218-28 pubmed publisher |
| Liu Y, Liu X, Hao W, Decker Y, Schomburg R, Fülöp L, et al. IKKβ deficiency in myeloid cells ameliorates Alzheimer's disease-related symptoms and pathology. J Neurosci. 2014;34:12982-99 pubmed publisher |
| Sierra R, Thevenot P, Raber P, Cui Y, Parsons C, Ochoa A, et al. Rescue of notch-1 signaling in antigen-specific CD8+ T cells overcomes tumor-induced T-cell suppression and enhances immunotherapy in cancer. Cancer Immunol Res. 2014;2:800-11 pubmed publisher |
| Zheng L, Liu H, Wang P, Song W, Sun X. Regulator of calcineurin 1 gene transcription is regulated by nuclear factor-kappaB. Curr Alzheimer Res. 2014;11:156-64 pubmed |
| Wong S, Chan S, Wong W, Wong P, Lai M. Andrographolide attenuates interleukin-1β-stimulated upregulation of chemokine CCL5 and glial fibrillary acidic protein in astrocytes. Neuroreport. 2014;25:881-6 pubmed publisher |
| Wang H, Hu B, Zou Y, Bo L, Wang J, Li J, et al. Dexmedetomidine premedication attenuates concanavalin A-induced hepatitis in mice. J Toxicol Sci. 2014;39:755-64 pubmed |
| Lavorgna A, Matsuoka M, Harhaj E. A critical role for IL-17RB signaling in HTLV-1 tax-induced NF-κB activation and T-cell transformation. PLoS Pathog. 2014;10:e1004418 pubmed publisher |
| Walzer K, Wier G, Dam R, Srinivasan A, Borges A, English E, et al. Hammondia hammondi harbors functional orthologs of the host-modulating effectors GRA15 and ROP16 but is distinguished from Toxoplasma gondii by a unique transcriptional profile. Eukaryot Cell. 2014;13:1507-18 pubmed publisher |
| Shambayati M, Patel M, Ma Y, Cunningham R, Schreihofer D. Central inflammatory response to experimental stroke is inhibited by a neuroprotective dose of dietary soy. Brain Res. 2014;1593:76-82 pubmed publisher |
| Caito S, Yu Y, Aschner M. Differential inflammatory response to acrylonitrile in rat primary astrocytes and microglia. Neurotoxicology. 2014;42:1-7 pubmed publisher |
| Hanami K, Nakano K, Saito K, Okada Y, Yamaoka K, Kubo S, et al. Dopamine D2-like receptor signaling suppresses human osteoclastogenesis. Bone. 2013;56:1-8 pubmed publisher |
| Wang Z, Zhao H, Peng S, Zuo Z. Intranasal pyrrolidine dithiocarbamate decreases brain inflammatory mediators and provides neuroprotection after brain hypoxia-ischemia in neonatal rats. Exp Neurol. 2013;249:74-82 pubmed publisher |
| Liu C, Wang G, Chen G, Mu Y, Zhang L, Hu X, et al. Huangqi decoction inhibits apoptosis and fibrosis, but promotes Kupffer cell activation in dimethylnitrosamine-induced rat liver fibrosis. BMC Complement Altern Med. 2012;12:51 pubmed publisher |
| Chattopadhyay M, Kodela R, Nath N, Barsegian A, Boring D, Kashfi K. Hydrogen sulfide-releasing aspirin suppresses NF-κB signaling in estrogen receptor negative breast cancer cells in vitro and in vivo. Biochem Pharmacol. 2012;83:723-32 pubmed publisher |
