HIP2 (D27C4) Rabbit mAb | Cell Signaling Technology 8226 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

HIP2 (D27C4) Rabbit mAb

catalog :

8226

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D27C4

reactivity :

human, mouse, rat, bovine

application :

western blot, immunoprecipitation

more info or order :

Cell Signaling Technology product webpage

citations: 19

Published Application/Species/Sample/Dilution	Reference
western blot; mouse	Lee S, Phipson B, Hyland C, Leong H, Allan R, Lun A, et al. Polycomb repressive complex 2 (PRC2) suppresses E?-myc lymphoma. Blood. 2013;122:2654-63 pubmed publisher
	Tamburri S, Lavarone E, Fernandez Perez D, Conway E, Zanotti M, Manganaro D, et al. Histone H2AK119 Mono-Ubiquitination Is Essential for Polycomb-Mediated Transcriptional Repression. Mol Cell. 2019;: pubmed publisher
	Blackledge N, Fursova N, Kelley J, Huseyin M, Feldmann A, Klose R. PRC1 Catalytic Activity Is Central to Polycomb System Function. Mol Cell. 2019;: pubmed publisher
	Bianchi M, Crinelli R, Giacomini E, Carloni E, Radici L, Scarpa E, et al. A negative feedback mechanism links UBC gene expression to ubiquitin levels by affecting RNA splicing rather than transcription. Sci Rep. 2019;9:18556 pubmed publisher
	Kuznetsov J, Agüero T, Owens D, Kurtenbach S, Field M, Durante M, et al. BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers. Sci Adv. 2019;5:eaax1738 pubmed publisher
	Healy E, Mucha M, Glancy E, Fitzpatrick D, Conway E, Neikes H, et al. PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation. Mol Cell. 2019;76:437-452.e6 pubmed publisher
	Lamb K, Bsteh D, Dishman S, Moussa H, Fan H, Stuckey J, et al. Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7. Cell Chem Biol. 2019;26:1365-1379.e22 pubmed publisher
	Turberfield A, Kondo T, Nakayama M, Koseki Y, King H, Koseki H, et al. KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity. Nucleic Acids Res. 2019;47:9005-9023 pubmed publisher
	Fursova N, Blackledge N, Nakayama M, Ito S, Koseki Y, Farcas A, et al. Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression. Mol Cell. 2019;74:1020-1036.e8 pubmed publisher
	de las Pozas A, Reiner T, De Cesare V, Trost M, Perez Stable C. Inhibiting Multiple Deubiquitinases to Reduce Androgen Receptor Expression in Prostate Cancer Cells. Sci Rep. 2018;8:13146 pubmed publisher
	Nishioka K, Miyazaki H, Soejima H. Unbiased shRNA screening, using a combination of FACS and high-throughput sequencing, enables identification of novel modifiers of Polycomb silencing. Sci Rep. 2018;8:12128 pubmed publisher
	Dardalhon Cuménal D, Deraze J, Dupont C, Ribeiro V, Coléno Costes A, Pouch J, et al. Cyclin G and the Polycomb Repressive complexes PRC1 and PR-DUB cooperate for developmental stability. PLoS Genet. 2018;14:e1007498 pubmed publisher
	Nagase R, Inoue D, Pastore A, Fujino T, Hou H, Yamasaki N, et al. Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation. J Exp Med. 2018;215:1729-1747 pubmed publisher
	Conway E, Jerman E, Healy E, Ito S, Holoch D, Oliviero G, et al. A Family of Vertebrate-Specific Polycombs Encoded by the LCOR/LCORL Genes Balance PRC2 Subtype Activities. Mol Cell. 2018;70:408-421.e8 pubmed publisher
	Kolluri K, Alifrangis C, Kumar N, Ishii Y, Price S, Michaut M, et al. Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells. elife. 2018;7: pubmed publisher
	Omori Y, Kubo S, Kon T, Furuhashi M, Narita H, Kominami T, et al. Samd7 is a cell type-specific PRC1 component essential for establishing retinal rod photoreceptor identity. Proc Natl Acad Sci U S A. 2017;114:E8264-E8273 pubmed publisher
	Wheaton K, Sarkari F, Stanly Johns B, Davarinejad H, Egorova O, Kaustov L, et al. UbE2E1/UBCH6 Is a Critical in Vivo E2 for the PRC1-catalyzed Ubiquitination of H2A at Lys-119. J Biol Chem. 2017;292:2893-2902 pubmed publisher
	Inagaki T, Iwasaki S, Matsumura Y, Kawamura T, Tanaka T, Abe Y, et al. The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis. J Biol Chem. 2015;290:4163-77 pubmed publisher
	Ji Z, Mohammed H, Webber A, Ridsdale J, Han N, Carroll J, et al. The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex. Nucleic Acids Res. 2014;42:6232-42 pubmed publisher

product information

SKU :

8226S

Product-Name :

HIP2 (D27C4) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, Mk, (B)

Applications :

Immunoprecipitation

Product-Category :

Ubiquitin and Ubiquitin-like proteins

Shipping-Temp :

COLD

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

HIP2

Primary-Protein :

Ube2k

Alt-Names :

DKFZp564C1216,DKFZp686J24237,E2(25K),E2-25K,HIP-2,HIP2,HYPG,Huntingtin-interacting protein 2,LIG,UBE2K,Ubiquitin carrier protein,Ubiquitin-conjugating enzyme E2 K,Ubiquitin-conjugating enzyme E2(25K),Ubiquitin-conjugating enzyme E2-25 kDa,Ubiquitin-conjugating enzyme E2-25K,Ubiquitin-protein ligase,huntingtin interacting protein 2,ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)

more info or order :

Cell Signaling Technology product webpage