ZO-1 (D7D12) Rabbit mAb | Cell Signaling Technology 8193 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

ZO-1 (D7D12) Rabbit mAb

catalog :

8193

clonality :

monoclonal

host :

rabbit

conjugate :

nonconjugated

clone name :

D7D12

reactivity :

human, mouse, pig

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

more info or order :

Cell Signaling Technology product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; fig 1a	Park G, Kim D. Cigarette smoke-induced EGFR activation promotes epithelial mesenchymal migration of human retinal pigment epithelial cells through regulation of the FAK-mediated Syk/Src pathway. Mol Med Rep. 2018;17:3563-3574 pubmed publisher
western blot; human; 1:1000; loading ...; fig 7j	Caino M, Seo J, Wang Y, Rivadeneira D, Gabrilovich D, Kim E, et al. Syntaphilin controls a mitochondrial rheostat for proliferation-motility decisions in cancer. J Clin Invest. 2017;127:3755-3769 pubmed publisher
western blot; human; loading ...; fig 2c	Chang Y, Lin T, Campbell M, Pan C, Lee S, Lee H, et al. REST is a crucial regulator for acquiring EMT-like and stemness phenotypes in hormone-refractory prostate cancer. Sci Rep. 2017;7:42795 pubmed publisher
western blot; human; loading ...; fig 4c	Zhai S, Liu C, Zhang L, Zhu J, Guo J, Zhang J, et al. PLCE1 Promotes Esophageal Cancer Cell Progression by Maintaining the Transcriptional Activity of Snail. Neoplasia. 2017;19:154-164 pubmed publisher
immunohistochemistry; mouse; loading ...; fig 8f	Zhang Q, Liu S, Parajuli K, Zhang W, Zhang K, Mo Z, et al. Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition. Oncogene. 2017;36:687-699 pubmed publisher
western blot; pig; 1:2000; fig 6A	Springler A, Hessenberger S, Schatzmayr G, Mayer E. Early Activation of MAPK p44/42 Is Partially Involved in DON-Induced Disruption of the Intestinal Barrier Function and Tight Junction Network. Toxins (Basel). 2016;8: pubmed publisher
western blot; human; 1:1000; loading ...; fig s8	Huang M, Liu T, Ma P, Mitteer R, Zhang Z, Kim H, et al. c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma. J Clin Invest. 2016;126:1801-14 pubmed publisher
western blot; human; fig 6	Wang F, Feng Y, Li P, Wang K, Feng L, Liu Y, et al. RASSF10 is an epigenetically inactivated tumor suppressor and independent prognostic factor in hepatocellular carcinoma. Oncotarget. 2016;7:4279-97 pubmed publisher
western blot; human; fig 7a	Yokdang N, Hatakeyama J, Wald J, Simion C, Tellez J, Chang D, et al. LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene. 2016;35:2932-47 pubmed publisher
western blot; human; loading ...; fig 8	Reuther C, Heinzle V, Spampatti M, Vlotides G, de Toni E, Spöttl G, et al. Cabozantinib and Tivantinib, but Not INC280, Induce Antiproliferative and Antimigratory Effects in Human Neuroendocrine Tumor Cells in vitro: Evidence for 'Off-Target' Effects Not Mediated by c-Met Inhibition. Neuroendocrinology. 2016;103:383-401 pubmed publisher
immunocytochemistry; human; fig 2 western blot; human; fig 2	Prasad S, Sajja R, Park J, Naik P, Kaisar M, Cucullo L. Impact of cigarette smoke extract and hyperglycemic conditions on blood-brain barrier endothelial cells. Fluids Barriers CNS. 2015;12:18 pubmed publisher
western blot; human; 1:300-500	Sajja R, Green K, Cucullo L. Altered Nrf2 signaling mediates hypoglycemia-induced blood-brain barrier endothelial dysfunction in vitro. PLoS ONE. 2015;10:e0122358 pubmed publisher
western blot; human	Soncini D, Caffa I, Zoppoli G, Cea M, Cagnetta A, Passalacqua M, et al. Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. J Biol Chem. 2014;289:34189-204 pubmed publisher
western blot; human	Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, et al. Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 2014;26:222-34 pubmed publisher
immunocytochemistry; human; 1:200 western blot; human; 1:500	Sajja R, Prasad S, Cucullo L. Impact of altered glycaemia on blood-brain barrier endothelium: an in vitro study using the hCMEC/D3 cell line. Fluids Barriers CNS. 2014;11:8 pubmed publisher
	Paltoglou S, Das R, Townley S, Hickey T, Tarulli G, Coutinho I, et al. Novel Androgen Receptor Coregulator GRHL2 Exerts Both Oncogenic and Antimetastatic Functions in Prostate Cancer. Cancer Res. 2017;77:3417-3430 pubmed publisher
	Faronato M, Nguyen V, Patten D, Lombardo Y, Steel J, Patel N, et al. DMXL2 drives epithelial to mesenchymal transition in hormonal therapy resistant breast cancer through Notch hyper-activation. Oncotarget. 2015;6:22467-79 pubmed
	Eurlings I, Reynaert N, van den Beucken T, Gosker H, de Theije C, Verhamme F, et al. Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1Î± in mesenchymal transition. PLoS ONE. 2014;9:e107757 pubmed publisher

product information

SKU :

8193S

Product-Name :

ZO-1 (D7D12) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, Mk

Applications :

Immunoprecipitation

Product-Category :

Cytoskeletal Signaling

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

220

Host :

Rabbit

Target :

ZO-1

Primary-Protein :

ZO1

Alt-Names :

DKFZp686M05161,MGC133289,TJP1,Tight junction protein 1,Tight junction protein ZO-1,ZO-1,ZO1,Zona occludens protein 1,Zonula occludens protein 1,tight junction protein 1 (zona occludens 1),zona occludens 1,zonula occludens 1 protein

more info or order :

Cell Signaling Technology product webpage