HMGA2 (D1A7) Rabbit mAb | Cell Signaling Technology 8179 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

HMGA2 (D1A7) Rabbit mAb

catalog :

8179

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D1A7

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Cell Signaling Technology product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4k, 4l, 6d western blot; mouse; fig s6a	Liu C, Zheng S, Wang Z, Wang S, Wang X, Yang L, et al. KRAS-G12D mutation drives immune suppression and the primary resistance of anti-PD-1/PD-L1 immunotherapy in non-small cell lung cancer. Cancer Commun (Lond). 2022;42:828-847 pubmed publisher
immunohistochemistry; rat; 1:100; loading ...; fig 4c	Frasson L, Dalmaso B, Akamine P, Kimura E, Hamassaki D, Del Debbio C. Let-7, Lin28 and Hmga2 Expression in Ciliary Epithelium and Retinal Progenitor Cells. Invest Ophthalmol Vis Sci. 2021;62:31 pubmed publisher
western blot; human; loading ...; fig 4a	Hiramoto H, Muramatsu T, Ichikawa D, Tanimoto K, Yasukawa S, Otsuji E, et al. miR-509-5p and miR-1243 increase the sensitivity to gemcitabine by inhibiting epithelial-mesenchymal transition in pancreatic cancer. Sci Rep. 2017;7:4002 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 3 immunohistochemistry - paraffin section; human; 1:400; loading ...; fig 1	Strell C, Norberg K, Mezheyeuski A, Schnittert J, Kuninty P, Moro C, et al. Stroma-regulated HMGA2 is an independent prognostic marker in PDAC and AAC. Br J Cancer. 2017;117:65-77 pubmed publisher
western blot; human; 1:1000; loading ...; fig 3b	Yang X, Zhao Q, Yin H, Lei X, Gan R. MiR-33b-5p sensitizes gastric cancer cells to chemotherapy drugs via inhibiting HMGA2 expression. J Drug Target. 2017;25:653-660 pubmed publisher
western blot; human; loading ...; fig 4c	Paladino D, Yue P, Furuya H, Acoba J, Rosser C, Turkson J. A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer. Oncotarget. 2016;7:7253-67 pubmed publisher
western blot; mouse; 1:1000; fig s1	Gökbuget D, Pereira J, Bachofner S, Marchais A, Ciaudo C, Stoffel M, et al. The Lin28/let-7 axis is critical for myelination in the peripheral nervous system. Nat Commun. 2015;6:8584 pubmed publisher
immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 3d	Madison B, Jeganathan A, Mizuno R, Winslow M, Castells A, Cuatrecasas M, et al. Let-7 Represses Carcinogenesis and a Stem Cell Phenotype in the Intestine via Regulation of Hmga2. PLoS Genet. 2015;11:e1005408 pubmed publisher
	Wang H, Sun Z, Wang Y, Hu Z, Zhou H, Zhang L, et al. miR-33-5p, a novel mechano-sensitive microRNA promotes osteoblast differentiation by targeting Hmga2. Sci Rep. 2016;6:23170 pubmed publisher
	Chang K, Lin S, Liu S, Yi J, Chien K, Chi L, et al. Low-molecular-mass secretome profiling identifies HMGA2 and MIF as prognostic biomarkers for oral cavity squamous cell carcinoma. Sci Rep. 2015;5:11689 pubmed publisher
	Alonso N, Guillen R, Chambers J, Leng F. A rapid and sensitive high-throughput screening method to identify compounds targeting protein-nucleic acids interactions. Nucleic Acids Res. 2015;43:e52 pubmed publisher
	Jin B, Wang Y, Wu C, Liu K, Chen H, Mao Z. PIM-1 modulates cellular senescence and links IL-6 signaling to heterochromatin formation. Aging Cell. 2014;13:879-89 pubmed publisher
	Chen K, Hou Y, Wang K, Li J, Xia Y, Yang X, et al. Reexpression of Let-7g microRNA inhibits the proliferation and migration via K-Ras/HMGA2/snail axis in hepatocellular carcinoma. Biomed Res Int. 2014;2014:742417 pubmed publisher
	Patel K, Kollory A, Takashima A, Sarkar S, Faller D, Ghosh S. MicroRNA let-7 downregulates STAT3 phosphorylation in pancreatic cancer cells by increasing SOCS3 expression. Cancer Lett. 2014;347:54-64 pubmed publisher

product information

SKU :

8179S

Product-Name :

HMGA2 (D1A7) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, R, (Mk)

Applications :

Immunofluorescence (Immunocytochemistry)

Product-Category :

Chromatin Regulation / Nuclear Function

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

HMGA2

Primary-Protein :

HMGA2

Alt-Names :

BABL,HMGA2,HMGI-C,HMGIC,High mobility group AT-hook protein 2,High mobility group protein HMGI-C,High-mobility group protein HMGI-C,LIPO,STQTL9,high mobility group AT-hook 2,high-mobility group (nonhistone chromosomal) protein isoform I-C

more info or order :

Cell Signaling Technology product webpage