product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
C/EBPα (D56F10) XP® Rabbit mAb
catalog :
8178
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D56F10
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 18
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; fig 3a
Cheng C, Xue F, Sui W, Meng L, Xie L, Zhang C, et al. Deletion of natriuretic peptide receptor C alleviates adipose tissue inflammation in hypercholesterolemic Apolipoprotein E knockout mice. J Cell Mol Med. 2021;25:9837-9850 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3d
Tamura T, Kodama T, Sato K, Murai K, Yoshioka T, Shigekawa M, et al. Dysregulation of PI3K and Hippo signaling pathways synergistically induces chronic pancreatitis via CTGF upregulation. J Clin Invest. 2021;131: pubmed publisher
  • western blot; human; loading ...
Chen Q, Liu X, Wang D, Zheng J, Chen L, Xie Q, et al. Periodontal Inflammation-Triggered by Periodontal Ligament Stem Cell Pyroptosis Exacerbates Periodontitis. Front Cell Dev Biol. 2021;9:663037 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 1b
Zhang L, Li M, Tian C, Wang T, Mi S. CCAAT enhancer binding protein α suppresses proliferation, metastasis, and epithelial-mesenchymal transition of ovarian cancer cells via suppressing the Wnt/β-catenin signaling. Neoplasma. 2021;68:602-612 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 6e
Zhang X, Chen X, Qi T, Kong Q, Cheng H, Cao X, et al. HSPA12A is required for adipocyte differentiation and diet-induced obesity through a positive feedback regulation with PPARγ. Cell Death Differ. 2019;: pubmed publisher
  • western blot; mouse; 1:100; loading ...; fig 3c
Song Z, Xiaoli A, Zhang Q, Zhang Y, Yang E, Wang S, et al. Cyclin C regulates adipogenesis by stimulating transcriptional activity of CCAAT/enhancer-binding protein ?. J Biol Chem. 2017;292:8918-8932 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 3a
  • western blot; mouse; loading ...; fig 3b
Dogan A, Demirci S, Apdik H, Bayrak O, Gulluoglu S, Tuysuz E, et al. A new hope for obesity management: Boron inhibits adipogenesis in progenitor cells through the Wnt/β-catenin pathway. Metabolism. 2017;69:130-142 pubmed publisher
  • western blot; mouse; fig s3d
  • western blot; human; fig 2b
Chan L, Chen Z, Braas D, Lee J, Xiao G, Geng H, et al. Metabolic gatekeeper function of B-lymphoid transcription factors. Nature. 2017;542:479-483 pubmed publisher
  • immunocytochemistry; mouse; 1:400; loading ...; fig 4
  • western blot; mouse; 1:1000; loading ...; fig 5a
Dogan A, Demirci S, Kıratlı B, Sahin F. Cytoglobin: a potential marker for adipogenic differentiation in preadipocytes in vitro. Cytotechnology. 2017;69:157-165 pubmed publisher
  • western blot; mouse; loading ...; fig 5a
Stein S, Mack E, Rome K, Pajcini K, Ohtani T, Xu L, et al. Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL. PLoS ONE. 2016;11:e0155408 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:500; fig 6a
  • western blot; mouse; 1:1000; fig 7f
  • immunohistochemistry - paraffin section; human; 1:500; loading ...; fig 7g
Lombardi R, Chen S, Ruggiero A, Gurha P, Czernuszewicz G, Willerson J, et al. Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene. Circ Res. 2016;119:41-54 pubmed publisher
  • western blot; human; 1:1000; fig 2
Senol Cosar O, Flach R, DiStefano M, Chawla A, Nicoloro S, Straubhaar J, et al. Tenomodulin promotes human adipocyte differentiation and beneficial visceral adipose tissue expansion. Nat Commun. 2016;7:10686 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Lim G, Albrecht T, Piske M, Sarai K, Lee J, Ramshaw H, et al. 14-3-3ζ coordinates adipogenesis of visceral fat. Nat Commun. 2015;6:7671 pubmed publisher
  • western blot; human; fig 2
Shi C, Zhang M, Tong M, Yang L, Pang L, Chen L, et al. miR-148a is Associated with Obesity and Modulates Adipocyte Differentiation of Mesenchymal Stem Cells through Wnt Signaling. Sci Rep. 2015;5:9930 pubmed publisher
  • western blot; human; fig s10b
Chen Z, Shojaee S, Buchner M, Geng H, Lee J, Klemm L, et al. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 2015;521:357-61 pubmed publisher
Obora K, Onodera Y, Takehara T, Frampton J, Hasei J, Ozaki T, et al. Inflammation-induced miRNA-155 inhibits self-renewal of neural stem cells via suppression of CCAAT/enhancer binding protein β (C/EBPβ) expression. Sci Rep. 2017;7:43604 pubmed publisher
Choi M, Kim H, Ham M, Choi D, Lee T, Shin D. Amber Light (590 nm) Induces the Breakdown of Lipid Droplets through Autophagy-Related Lysosomal Degradation in Differentiated Adipocytes. Sci Rep. 2016;6:28476 pubmed publisher
Wang Q, Tao C, Jiang L, Shao M, Ye R, Zhu Y, et al. Distinct regulatory mechanisms governing embryonic versus adult adipocyte maturation. Nat Cell Biol. 2015;17:1099-111 pubmed publisher
product information
SKU :
8178P
Product-Name :
C/EBPα (D56F10) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, (R, Z)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Metabolism
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
42, 28
Host :
Rabbit
Target :
C/EBP-alpha
Primary-Protein :
C/EBP-alpha
Alt-Names :
C/EBP alpha,C/EBP-alpha,CCAAT/enhancer binding protein (C/EBP), alpha,CCAAT/enhancer-binding protein alpha,CEBP,CEBPA
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.