product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
LAMTOR2/ROBLD3 (D7C10) Rabbit mAb
catalog :
8145
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D7C10
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig s6a
  • western blot; human; loading ...; fig s5c, s6b
Nakatani T, Tsujimoto K, Park J, Jo T, Kimura T, Hayama Y, et al. The lysosomal Ragulator complex plays an essential role in leukocyte trafficking by activating myosin II. Nat Commun. 2021;12:3333 pubmed publisher
  • western blot; mouse; loading ...; fig s2g
He M, Chaurushiya M, Webster J, Kummerfeld S, Reja R, Chaudhuri S, et al. Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1. Science. 2019;364:283-285 pubmed publisher
  • western blot; mouse; loading ...; fig 3c
Kissing S, Rudnik S, Damme M, Lüllmann Rauch R, Ichihara A, Kornak U, et al. Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes. Autophagy. 2017;13:670-685 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig s1c
Kimura T, Nada S, Takegahara N, Okuno T, Nojima S, Kang S, et al. Polarization of M2 macrophages requires Lamtor1 that integrates cytokine and amino-acid signals. Nat Commun. 2016;7:13130 pubmed publisher
  • western blot; human; 1:1000; fig s2
Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed publisher
Lin C, Nozawa T, Minowa Nozawa A, Toh H, Aikawa C, Nakagawa I. LAMTOR2/LAMTOR1 complex is required for TAX1BP1-mediated xenophagy. Cell Microbiol. 2019;21:e12981 pubmed publisher
Jia J, Abudu Y, Claude Taupin A, Gu Y, Kumar S, Choi S, et al. Galectins Control mTOR in Response to Endomembrane Damage. Mol Cell. 2018;70:120-135.e8 pubmed publisher
Zheng K, Jiang Y, Liao C, Hu X, Li Y, Zeng Y, et al. NOX2-Mediated TFEB Activation and Vacuolization Regulate Lysosome-Associated Cell Death Induced by Gypenoside L, a Saponin Isolated from Gynostemma pentaphyllum. J Agric Food Chem. 2017;65:6625-6637 pubmed publisher
product information
SKU :
8145S
Product-Name :
LAMTOR2/ROBLD3 (D7C10) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
PI3K / Akt Signaling
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
14
Host :
Rabbit
Target :
LAMTOR2
Primary-Protein :
LAMTOR2
Alt-Names :
ENDAP,HSPC003,MAPBPIP,MAPKSP1 adaptor protein,MAPKSP1AP,P14,ROBLD3,Ragulator2,endosomal adaptor protein p14,late endosomal/lysosomal Mp1-interacting protein,late endosomal/lysosomal adaptor, MAPK and MTOR activator 2,mitogen-activated protein-binding protein-interacting protein,roadblock domain containing 3,roadblock domain-containing protein 3
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.