product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Rab10 (D36C4) XP® Rabbit mAb
catalog :
8127
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D36C4
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 13
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 4b
  • western blot; human; loading ...; fig 1a
Puri C, Vicinanza M, Ashkenazi A, Gratian M, Zhang Q, Bento C, et al. The RAB11A-Positive Compartment Is a Primary Platform for Autophagosome Assembly Mediated by WIPI2 Recognition of PI3P-RAB11A. Dev Cell. 2018;45:114-131.e8 pubmed publisher
  • western blot; human; loading ...; fig 1b
Purlyte E, Dhekne H, Sarhan A, Gomez R, Lis P, Wightman M, et al. Rab29 activation of the Parkinson's disease-associated LRRK2 kinase. EMBO J. 2018;37:1-18 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6a
Fan Y, Howden A, Sarhan A, Lis P, Ito G, Martinez T, et al. Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils. Biochem J. 2018;475:23-44 pubmed publisher
  • western blot; human; loading ...; fig 2e
Steger M, Diez F, Dhekne H, Lis P, Nirujogi R, Karayel Ö, et al. Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. elife. 2017;6: pubmed publisher
  • western blot; mouse; loading ...; fig 5a
Gulbranson D, Davis E, Demmitt B, Ouyang Y, Ye Y, Yu H, et al. RABIF/MSS4 is a Rab-stabilizing holdase chaperone required for GLUT4 exocytosis. Proc Natl Acad Sci U S A. 2017;114:E8224-E8233 pubmed publisher
  • immunoprecipitation; human; loading ...; fig 3b
  • western blot; human; loading ...; fig 3b
Lin Y, Ke C, Wang Y, Chen M, Chen T, Ku W, et al. RAB10 Interacts with the Male Germ Cell-Specific GTPase-Activating Protein during Mammalian Spermiogenesis. Int J Mol Sci. 2017;18: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2a
Ito G, Katsemonova K, Tonelli F, Lis P, Baptista M, Shpiro N, et al. Phos-tag analysis of Rab10 phosphorylation by LRRK2: a powerful assay for assessing kinase function and inhibitors. Biochem J. 2016;473:2671-85 pubmed publisher
  • immunocytochemistry; rat; fig 2
Homma Y, Fukuda M. Rabin8 regulates neurite outgrowth in both GEF activity-dependent and -independent manners. Mol Biol Cell. 2016;27:2107-18 pubmed publisher
  • western blot; rat
Romero A, Renau Piqueras J, Marín M, Esteban Pretel G. Chronic alcohol exposure affects the cell components involved in membrane traffic in neuronal dendrites. Neurotox Res. 2015;27:43-54 pubmed publisher
  • immunocytochemistry; mouse
Lalioti V, Ilari A, O Connell D, Poser E, Sandoval I, Colotti G. Sorcin links calcium signaling to vesicle trafficking, regulates Polo-like kinase 1 and is necessary for mitosis. PLoS ONE. 2014;9:e85438 pubmed publisher
Jeng E, Bhadkamkar V, Ibe N, Gause H, Jiang L, Chan J, et al. Systematic Identification of Host Cell Regulators of Legionella pneumophila Pathogenesis Using a Genome-wide CRISPR Screen. Cell Host Microbe. 2019;26:551-563.e6 pubmed publisher
Gerondopoulos A, Bastos R, Yoshimura S, Anderson R, Carpanini S, Aligianis I, et al. Rab18 and a Rab18 GEF complex are required for normal ER structure. J Cell Biol. 2014;205:707-20 pubmed publisher
English A, Voeltz G. Rab10 GTPase regulates ER dynamics and morphology. Nat Cell Biol. 2013;15:169-78 pubmed publisher
product information
SKU :
8127P
Product-Name :
Rab10 (D36C4) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Protein Folding and Trafficking
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
23
Host :
Rabbit
Target :
Rab10
Primary-Protein :
Rab10
Alt-Names :
GTP-binding protein RAB10,RAB10,RAB10, member RAS oncogene family,Ras-related protein Rab-10,ras-related GTP-binding protein
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.