product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
KEAP1 (D6B12) Rabbit mAb
catalog :
8047S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
reactivity :
human, mouse, rat, cow
application :
western blot, immunocytochemistry
more info or order :
Cell Signaling Technology product webpage
citations: 5
Published Application/Species/DilutionReference
  • western blot (knockdown validation); rat; fig 3
Ashino T, Yamamoto M, Numazawa S. Nrf2/Keap1 system regulates vascular smooth muscle cell apoptosis for vascular homeostasis: role in neointimal formation after vascular injury. Sci Rep. 2016;6:26291 pubmed publisher
  • western blot; human; fig 2a
Kabaria S, Choi D, Chaudhuri A, Jain M, Li H, Junn E. MicroRNA-7 activates Nrf2 pathway by targeting Keap1 expression. Free Radic Biol Med. 2015;89:548-56 pubmed publisher
  • western blot; mouse; fig 6a
Tomasovic A, Kurrle N, Sürün D, Heidler J, Husnjak K, Poser I, et al. Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions. J Biol Chem. 2015;290:9738-52 pubmed publisher
  • western blot; rat; 1:1000
Padiya R, Chowdhury D, Borkar R, Srinivas R, Pal Bhadra M, Banerjee S. Garlic attenuates cardiac oxidative stress via activation of PI3K/AKT/Nrf2-Keap1 pathway in fructose-fed diabetic rat. PLoS ONE. 2014;9:e94228 pubmed publisher
Orimoto A, Suzuki T, Ueno A, Kawai T, Nakamura H, Kanamori T. Effect of 2-hydroxyethyl methacrylate on antioxidant responsive element-mediated transcription: a possible indication of its cytotoxicity. PLoS ONE. 2013;8:e58907 pubmed publisher
product information
SKU :
8047S
Product-Name :
KEAP1 (D6B12) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, (Mk, B, Pg)
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Ubiquitin and Ubiquitin-like proteins
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
60-64
Host :
Rabbit
Target :
KEAP1
Primary-Protein :
KEAP1
Alt-Names :
Cytosolic inhibitor of Nrf2,INRF2,KEAP1,KIAA0132,KLHL19,Kelch-like ECH-associated protein 1,Kelch-like protein 19,MGC10630,MGC1114,MGC20887,MGC4407,MGC9454
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.