product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Histone H2A.X (D17A3) XP® Rabbit mAb
catalog :
7631
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D17A3
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
Cell Signaling Technology product webpage
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig s8a
Chu S, Chabon J, Matovina C, Minehart J, Chen B, Zhang J, et al. Loss of H3K36 Methyltransferase SETD2 Impairs V(D)J Recombination during Lymphoid Development. iScience. 2020;23:100941 pubmed publisher
  • western blot; mouse; loading ...; fig s6f
Gronke K, Hernandez P, Zimmermann J, Klose C, Kofoed Branzk M, Guendel F, et al. Interleukin-22 protects intestinal stem cells against genotoxic stress. Nature. 2019;566:249-253 pubmed publisher
  • western blot; human; loading ...; fig 4b
Bononi A, Giorgi C, Patergnani S, Larson D, Verbruggen K, Tanji M, et al. BAP1 regulates IP3R3-mediated Ca2+ flux to mitochondria suppressing cell transformation. Nature. 2017;546:549-553 pubmed publisher
  • western blot; human; loading ...; fig 1c
Liu Y, Long Y, Wang S, Li Y, Zhang J. Phosphorylation of H2A.XTyr39 positively regulates DNA damage response and is linked to cancer progression. FEBS J. 2016;283:4462-4473 pubmed publisher
  • immunocytochemistry; human; fig 3b
  • western blot; human; fig 3d
Peng Y, Miao H, Wu S, Yang W, Zhang Y, Xie G, et al. ABHD5 interacts with BECN1 to regulate autophagy and tumorigenesis of colon cancer independent of PNPLA2. Autophagy. 2016;12:2167-2182 pubmed
  • immunocytochemistry; human; 1:150; fig 3
  • western blot; human; fig 3
Waye S, Naeem A, Choudhry M, Parasido E, Tricoli L, Sivakumar A, et al. The p53 tumor suppressor protein protects against chemotherapeutic stress and apoptosis in human medulloblastoma cells. Aging (Albany NY). 2015;7:854-68 pubmed
  • western blot; human; fig 9
Wu S, Guo Z, Hopkins C, Wei N, Chu E, Wipf P, et al. Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells. Oncotarget. 2015;6:40866-79 pubmed publisher
  • western blot; human; fig 1
Hollingworth R, Skalka G, Stewart G, Hislop A, Blackbourn D, Grand R. Activation of DNA Damage Response Pathways during Lytic Replication of KSHV. Viruses. 2015;7:2908-27 pubmed publisher
Liu J, Srinivasan S, Li C, Ho I, Rose J, Shaheen M, et al. Pooled library screening with multiplexed Cpf1 library. Nat Commun. 2019;10:3144 pubmed publisher
Kimura Y, Negishi H, Matsuda A, Endo N, Hangai S, Inoue A, et al. Novel chemical compound SINCRO with dual function in STING-type I interferon and tumor cell death pathways. Cancer Sci. 2018;109:2687-2696 pubmed publisher
Kedves A, Gleim S, Liang X, Bonal D, Sigoillot F, Harbinski F, et al. Recurrent ubiquitin B silencing in gynecological cancers establishes dependence on ubiquitin C. J Clin Invest. 2017;127:4554-4568 pubmed publisher
Okazaki A, Gameiro P, Christodoulou D, Laviollette L, Schneider M, Chaves F, et al. Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers. J Clin Invest. 2017;127:1631-1645 pubmed publisher
Mardakheh F, Sailem H, Kümper S, Tape C, McCully R, Paul A, et al. Proteomics profiling of interactome dynamics by colocalisation analysis (COLA). Mol Biosyst. 2016;13:92-105 pubmed
Cui T, Srivastava A, Han C, Yang L, Zhao R, Zou N, et al. XPC inhibits NSCLC cell proliferation and migration by enhancing E-Cadherin expression. Oncotarget. 2015;6:10060-72 pubmed
product information
SKU :
7631P
Product-Name :
Histone H2A.X (D17A3) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
15
Host :
Rabbit
Target :
H2AX
Primary-Protein :
H2AX
Alt-Names :
H2A histone family, member X,H2A.X,H2AFX,H2AX,H2AX histone,H2a/x,Histone H2A.x
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.