product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
HDAC6 (D21B10) Rabbit mAb
catalog :
7612
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D21B10
reactivity :
human, mouse, rat
application :
western blot, immunoprecipitation
citations: 9
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 10a, 10b, 10c
Urdiciain A, Erausquin E, Zelaya M, Zazpe I, Lanciego J, Melendez B, et al. Silencing of Histone Deacetylase 6 Decreases Cellular Malignancy and Contributes to Primary Cilium Restoration, Epithelial-to-Mesenchymal Transition Reversion, and Autophagy Inhibition in Glioblastoma Cell Lines. Biology (Basel). 2021;10: pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 3a
Magupalli V, Negro R, Tian Y, Hauenstein A, Di Caprio G, Skillern W, et al. HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. Science. 2020;369: pubmed publisher
  • western blot; human; loading ...; fig s1a
  • western blot; mouse; loading ...; fig 2b
Raghu D, Mobley R, Shendy N, Perry C, Abell A. GALNT3 Maintains the Epithelial State in Trophoblast Stem Cells. Cell Rep. 2019;26:3684-3697.e7 pubmed publisher
  • immunoprecipitation; mouse; fig 1b
  • western blot; mouse; 1:1000; fig 2a
Mo Z, Zhao X, Liu H, Hu Q, Chen X, Pham J, et al. Aberrant GlyRS-HDAC6 interaction linked to axonal transport deficits in Charcot-Marie-Tooth neuropathy. Nat Commun. 2018;9:1007 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 2a
Bitler B, Wu S, Park P, Hai Y, Aird K, Wang Y, et al. ARID1A-mutated ovarian cancers depend on HDAC6 activity. Nat Cell Biol. 2017;19:962-973 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 1a
Tan Y, Ci Y, Dai X, Wu F, Guo J, Liu D, et al. Cullin 3SPOP ubiquitin E3 ligase promotes the poly-ubiquitination and degradation of HDAC6. Oncotarget. 2017;8:47890-47901 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 7a
Choi S, Piao Z, Jin L, Kim J, Kim G, Ryu Y, et al. Piceatannol Attenuates Renal Fibrosis Induced by Unilateral Ureteral Obstruction via Downregulation of Histone Deacetylase 4/5 or p38-MAPK Signaling. PLoS ONE. 2016;11:e0167340 pubmed publisher
  • western blot; mouse; 1:500; fig 2
Pujol Lopez Y, Kenis G, Stettinger W, Neumeier K, De Jonge S, Steinbusch H, et al. Effects of prenatal Poly I:C exposure on global histone deacetylase (HDAC) and DNA methyltransferase (DNMT) activity in the mouse brain. Mol Biol Rep. 2016;43:711-7 pubmed publisher
Patel H, Stavrou I, Shrestha R, Draviam V, Frame M, Brunton V. Kindlin1 regulates microtubule function to ensure normal mitosis. J Mol Cell Biol. 2016;8:338-48 pubmed publisher
product information
SKU :
7612S
Product-Name :
HDAC6 (D21B10) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
140
Host :
Rabbit
Target :
HDAC6
Primary-Protein :
HDAC6
Alt-Names :
FLJ16239,HD6,HDAC6,Histone deacetylase 6,JM21,KIAA0901
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.