product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
CBP (D6C5) Rabbit mAb
catalog :
7389
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D6C5
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - frozen section, proximity ligation assay, RNA immunoprecipitation
citations: 18
Published Application/Species/Sample/DilutionReference
  • proximity ligation assay; human; loading ...; fig 4d
  • western blot; human; loading ...; fig 4f
Shen M, Zhang R, Jia W, Zhu Z, Zhao X, Zhao L, et al. Nuclear scaffold protein p54nrb/NONO facilitates the hypoxia-enhanced progression of hepatocellular carcinoma. Oncogene. 2021;40:4167-4183 pubmed publisher
  • western blot; mouse; loading ...
Shin M, Vázquez Rosa E, Koh Y, Dhar M, Chaubey K, Cintrón Pérez C, et al. Reducing acetylated tau is neuroprotective in brain injury. Cell. 2021;184:2715-2732.e23 pubmed publisher
  • western blot; rat; loading ...; fig 4b
  • immunoprecipitation; mouse; loading ...; fig 7k
  • immunohistochemistry - frozen section; human; loading ...; fig 7j
  • western blot; human; loading ...; fig 1b
Gao R, Chakraborty A, Geater C, Pradhan S, Gordon K, Snowden J, et al. Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. elife. 2019;8: pubmed publisher
  • western blot; mouse; 1:500; loading ...; fig 1a
Martins V, Dent J, Svensson K, Tahvilian S, Begur M, Lakkaraju S, et al. Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity. Am J Physiol Endocrinol Metab. 2019;: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 5b
  • flow cytometry; mouse; loading ...; fig 5a
Casey A, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, et al. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. J Cell Biol. 2018;217:2951-2974 pubmed publisher
  • chromatin immunoprecipitation; human; loading ...; fig 5e
Lin Y, Lin Y, Huang M, Kuo P, Wu C, Lee M, et al. Tumor necrosis factor-alpha inhibitors suppress CCL2 chemokine in monocytes via epigenetic modification. Mol Immunol. 2017;83:82-91 pubmed publisher
  • western blot; human; loading ...; fig 6f
Endorf E, Qing H, Aono J, Terami N, Doyon G, Hyzny E, et al. Telomerase Reverse Transcriptase Deficiency Prevents Neointima Formation Through Chromatin Silencing of E2F1 Target Genes. Arterioscler Thromb Vasc Biol. 2017;37:301-311 pubmed publisher
  • RNA immunoprecipitation; human; fig 3
  • western blot; human; fig s3
G Hendrickson D, Kelley D, Tenen D, BERNSTEIN B, Rinn J. Widespread RNA binding by chromatin-associated proteins. Genome Biol. 2016;17:28 pubmed publisher
  • western blot; human; loading ...; fig 5b
Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D, et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33 pubmed publisher
  • chromatin immunoprecipitation; mouse; fig 7d
  • immunoprecipitation; mouse; fig 8c
  • western blot; mouse; fig 8c
Zha L, Li F, Wu R, Artinian L, Rehder V, Yu L, et al. The Histone Demethylase UTX Promotes Brown Adipocyte Thermogenic Program Via Coordinated Regulation of H3K27 Demethylation and Acetylation. J Biol Chem. 2015;290:25151-63 pubmed publisher
  • chromatin immunoprecipitation; human; fig s6
  • western blot; human; fig 3
Walker M, Stopford C, Cederlund M, Fang F, Jahn C, Rabinowitz A, et al. FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma. Sci Signal. 2015;8:ra12 pubmed publisher
  • chromatin immunoprecipitation; mouse; 2 mg/ml; fig 2
  • chromatin immunoprecipitation; human; 2 mg/ml; fig s1
Xu M, Nagati J, Xie J, Li J, Walters H, Moon Y, et al. An acetate switch regulates stress erythropoiesis. Nat Med. 2014;20:1018-26 pubmed publisher
Hashwah H, Schmid C, Kasser S, Bertram K, Stelling A, Manz M, et al. Inactivation of CREBBP expands the germinal center B cell compartment, down-regulates MHCII expression and promotes DLBCL growth. Proc Natl Acad Sci U S A. 2017;114:9701-9706 pubmed publisher
Fettig L, McGinn O, Finlay Schultz J, LaBarbera D, Nordeen S, Sartorius C. Cross talk between progesterone receptors and retinoic acid receptors in regulation of cytokeratin 5-positive breast cancer cells. Oncogene. 2017;36:6074-6084 pubmed publisher
Alver B, Kim K, Lu P, Wang X, Manchester H, Wang W, et al. The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers. Nat Commun. 2017;8:14648 pubmed publisher
Carlson H, Quinn J, Yang Y, Thornburg C, Chang H, Stadler H. LncRNA-HIT Functions as an Epigenetic Regulator of Chondrogenesis through Its Recruitment of p100/CBP Complexes. PLoS Genet. 2015;11:e1005680 pubmed publisher
Wang Y, Wang Y, Luo M, Wu H, Kong L, Xin Y, et al. Novel curcumin analog C66 prevents diabetic nephropathy via JNK pathway with the involvement of p300/CBP-mediated histone acetylation. Biochim Biophys Acta. 2015;1852:34-46 pubmed publisher
Guo W, Lu J, Dai M, Wu T, Yu Z, Wang J, et al. Transcriptional coactivator CBP upregulates hTERT expression and tumor growth and predicts poor prognosis in human lung cancers. Oncotarget. 2014;5:9349-61 pubmed
product information
SKU :
7389S
Product-Name :
CBP (D6C5) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Chromatin Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
300
Host :
Rabbit
Target :
CBP
Primary-Protein :
CBP
Alt-Names :
CBP,CREB binding protein,CREB-binding protein,CREBBP,KAT3A,RSTS
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.