product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Human TNF-α Neutralizing (D1B4) Rabbit mAb
catalog :
7321
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D1B4
reactivity :
human, rat
application :
blocking or activating experiments, other
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • blocking or activating experiments; rat; 150 ug/ul; loading ...; fig s3d
Liddelow S, Guttenplan K, Clarke L, Bennett F, Bohlen C, Schirmer L, et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature. 2017;541:481-487 pubmed publisher
  • blocking or activating experiments; human; fig 3b
Lin C, Lin W, Cho R, Wang C, Hsiao L, Yang C. TNF-?-Induced cPLA2 Expression via NADPH Oxidase/Reactive Oxygen Species-Dependent NF-?B Cascade on Human Pulmonary Alveolar Epithelial Cells. Front Pharmacol. 2016;7:447 pubmed
  • blocking or activating experiments; human; fig 10
Li Y, Long X, Huang L, Yang M, Yuan Y, Wang Y, et al. Epstein-Barr Virus BZLF1-Mediated Downregulation of Proinflammatory Factors Is Essential for Optimal Lytic Viral Replication. J Virol. 2016;90:887-903 pubmed publisher
  • other; human; loading ...; fig 5c
Benzina S, Harquail J, Jean S, Beauregard A, Colquhoun C, Carroll M, et al. Deoxypodophyllotoxin isolated from Juniperus communis induces apoptosis in breast cancer cells. Anticancer Agents Med Chem. 2015;15:79-88 pubmed
  • blocking or activating experiments; human
Altonsy M, Sasse S, Phang T, Gerber A. Context-dependent cooperation between nuclear factor ?B (NF-?B) and the glucocorticoid receptor at a TNFAIP3 intronic enhancer: a mechanism to maintain negative feedback control of inflammation. J Biol Chem. 2014;289:8231-9 pubmed publisher
Muvaffak A, Pan Q, Yan H, Fernandez R, Lim J, Dolinski B, et al. Evaluating TBK1 as a therapeutic target in cancers with activated IRF3. Mol Cancer Res. 2014;12:1055-66 pubmed publisher
Blaauboer S, Gabrielle V, Jin L. MPYS/STING-mediated TNF-?, not type I IFN, is essential for the mucosal adjuvant activity of (3'-5')-cyclic-di-guanosine-monophosphate in vivo. J Immunol. 2014;192:492-502 pubmed publisher
product information
SKU :
7321S
Product-Name :
Human TNF-α Neutralizing (D1B4) Rabbit mAb
Size :
100 ug
Price-(USD) :
321 USD
Species-x-Reactivity :
H
Product-Category :
Immunology and Inflammation
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
Host :
Rabbit
Target :
TNF-alpha
Primary-Protein :
TNF-a
Alt-Names :
APC1 protein,Cachectin,DIF,TNF,TNF superfamily, member 2,TNF, macrophage-derived,TNF, monocyte-derived,TNF-a,TNF-alpha,TNFA,TNFSF2,Tumor necrosis factor,Tumor necrosis factor ligand superfamily member 2,Tumor necrosis factor, membrane form,Tumor necrosis factor, soluble form,tumor necrosis factor (TNF superfamily, member 2),tumor necrosis factor alpha
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.