product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Cleaved Caspase-9 (Asp330) (D2D4) Rabbit mAb
catalog :
7237
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D2D4
reactivity :
human, mouse
application :
western blot, immunoprecipitation
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 5e
Yue X, Zuo Y, Ke H, Luo J, Lou L, Qin W, et al. Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase. Biochem Pharmacol. 2017;137:29-50 pubmed publisher
  • western blot; human; loading ...; fig 7c
Sun J, Liu X, Gao H, Zhang L, Ji Q, Wang Z, et al. Overexpression of colorectal cancer oncogene CHRDL2 predicts a poor prognosis. Oncotarget. 2017;8:11489-11506 pubmed publisher
  • western blot; human; 1:500; loading ...; fig 2c
Morishita M, Kawamoto T, Hara H, Onishi Y, Ueha T, Minoda M, et al. AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway. Int J Oncol. 2017;50:23-30 pubmed publisher
  • western blot; human; loading ...; fig 2c
Chou H, Fong Y, Lin H, Tsai E, Chen J, Chang W, et al. An Acetamide Derivative as a Camptothecin Sensitizer for Human Non-Small-Cell Lung Cancer Cells through Increased Oxidative Stress and JNK Activation. Oxid Med Cell Longev. 2016;2016:9128102 pubmed
  • western blot; human; loading ...; fig 4a
Fritsch J, Fickers R, Klawitter J, Särchen V, Zingler P, Adam D, et al. TNF induced cleavage of HSP90 by cathepsin D potentiates apoptotic cell death. Oncotarget. 2016;7:75774-75789 pubmed publisher
  • western blot; human; loading ...; fig 2a
Li H, Yang X, Wang G, Li X, Tao D, Hu J, et al. KDM4B plays an important role in mitochondrial apoptosis by upregulating HAX1 expression in colorectal cancer. Oncotarget. 2016;7:57866-57877 pubmed publisher
  • western blot; mouse; loading ...; fig 7
Wang Y, Xu S, Xu W, Yang H, Hu P, Li Y. Sodium formate induces autophagy and apoptosis via the JNK signaling pathway of photoreceptor cells. Mol Med Rep. 2016;13:1111-8 pubmed publisher
  • western blot; human; 1:1000; fig 2b
Popp M, Maquat L. Attenuation of nonsense-mediated mRNA decay facilitates the response to chemotherapeutics. Nat Commun. 2015;6:6632 pubmed publisher
  • western blot; human; 1:1000; fig 8
Park J, Lee S, Yang S, Yoo H, Park J, Seong M, et al. Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage. Nat Commun. 2014;5:5483 pubmed publisher
Pitman R, Wojdyla L, Puri N. Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma. Oncotarget. 2013;4:761-71 pubmed
Katayama M, Donai K, Sakakibara H, Ohtomo Y, Miyagawa M, Kuroda K, et al. Coffee consumption delays the hepatitis and suppresses the inflammation related gene expression in the Long-Evans Cinnamon rat. Clin Nutr. 2014;33:302-10 pubmed publisher
Jiang H, Khan S, Wang Y, Charron G, He B, Sebastian C, et al. SIRT6 regulates TNF-? secretion through hydrolysis of long-chain fatty acyl lysine. Nature. 2013;496:110-3 pubmed publisher
product information
SKU :
7237S
Product-Name :
Cleaved Caspase-9 (Asp330) (D2D4) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, (Mk)
Applications :
Immunoprecipitation
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
37
Host :
Rabbit
Target :
Casp9 (Asp330, 17 kD) cleaved
Primary-Protein :
Casp9
Alt-Names :
APAF-3,APAF3,Apoptotic protease Mch-6,Apoptotic protease-activating factor 3,CASP-9,CASP9,CASPASE-9c,Caspase-9,Caspase-9 subunit p10,Caspase-9 subunit p35,ICE-LAP6,ICE-like apoptotic protease 6,MCH6,apoptotic protease activating factor 3,caspase 9, apoptosis-related cysteine peptidase,caspase 9, apoptosis-related cysteine protease
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.