product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
c-IAP1 (D5G9) Rabbit mAb
catalog :
7065
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D5G9
reactivity :
human
application :
western blot, immunoprecipitation
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig s5c
Fauster A, Rebsamen M, Willmann K, César Razquin A, Girardi E, Bigenzahn J, et al. Systematic genetic mapping of necroptosis identifies SLC39A7 as modulator of death receptor trafficking. Cell Death Differ. 2019;26:1138-1155 pubmed publisher
  • western blot; human; loading ...; fig 5a
Wang H, Bu L, Wang C, Zhang Y, Zhou H, Zhang X, et al. The Hsp70 inhibitor 2-phenylethynesulfonamide inhibits replication and carcinogenicity of Epstein-Barr virus by inhibiting the molecular chaperone function of Hsp70. Cell Death Dis. 2018;9:734 pubmed publisher
  • western blot; human; loading ...; fig 2a
Ma W, Tummers B, van Esch E, Goedemans R, Melief C, Meyers C, et al. Human Papillomavirus Downregulates the Expression of IFITM1 and RIPK3 to Escape from IFN?- and TNF?-Mediated Antiproliferative Effects and Necroptosis. Front Immunol. 2016;7:496 pubmed
  • western blot; human; loading ...; fig s4b
Klingbeil O, Lesche R, Gelato K, Haendler B, Lejeune P. Inhibition of BET bromodomain-dependent XIAP and FLIP expression sensitizes KRAS-mutated NSCLC to pro-apoptotic agents. Cell Death Dis. 2016;7:e2365 pubmed publisher
  • western blot; human; loading ...
Waguia Kontchou C, Tzivelekidis T, Gentle I, Hacker G. Infection of epithelial cells with Chlamydia trachomatis inhibits TNF-induced apoptosis at the level of receptor internalization while leaving non-apoptotic TNF-signalling intact. Cell Microbiol. 2016;18:1583-1595 pubmed publisher
  • western blot; human; fig 4
Monian P, Jiang X. The Cellular Apoptosis Susceptibility Protein (CAS) Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis and Cell Proliferation. J Biol Chem. 2016;291:2379-88 pubmed publisher
  • western blot; human
Greenfeld H, Takasaki K, Walsh M, Ersing I, Bernhardt K, Ma Y, et al. TRAF1 Coordinates Polyubiquitin Signaling to Enhance Epstein-Barr Virus LMP1-Mediated Growth and Survival Pathway Activation. PLoS Pathog. 2015;11:e1004890 pubmed publisher
  • western blot; human; 1:500
Luk S, Xue H, Cheng H, Lin D, Gout P, Fazli L, et al. The BIRC6 gene as a novel target for therapy of prostate cancer: dual targeting of inhibitors of apoptosis. Oncotarget. 2014;5:6896-908 pubmed
Kawalkowska J, Ogbechi J, Venables P, Williams R. cIAP1/2 inhibition synergizes with TNF inhibition in autoimmunity by down-regulating IL-17A and inducing Tregs. Sci Adv. 2019;5:eaaw5422 pubmed publisher
McCabe K, Bacos K, Lu D, Delaney J, Axelrod J, Potter M, et al. Triggering necroptosis in cisplatin and IAP antagonist-resistant ovarian carcinoma. Cell Death Dis. 2014;5:e1496 pubmed publisher
Jiang H, Khan S, Wang Y, Charron G, He B, Sebastian C, et al. SIRT6 regulates TNF-α secretion through hydrolysis of long-chain fatty acyl lysine. Nature. 2013;496:110-3 pubmed publisher
Keshari R, Jyoti A, Dubey M, Kothari N, Kohli M, Bogra J, et al. Cytokines induced neutrophil extracellular traps formation: implication for the inflammatory disease condition. PLoS ONE. 2012;7:e48111 pubmed publisher
product information
SKU :
7065S
Product-Name :
c-IAP1 (D5G9) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, (Mk)
Applications :
Immunoprecipitation
Product-Category :
Apoptosis
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
62
Host :
Rabbit
Target :
c-IAP1
Primary-Protein :
BIRC2
Alt-Names :
API1,BIRC2,Baculoviral IAP repeat-containing protein 2,C-IAP1,IAP homolog B,IAP-2,IAP2,Inhibitor of apoptosis protein 2,MIHB,NFR2-TRAF signalling complex protein,RING finger protein 48,RNF48,TNFR2-TRAF-signaling complex protein 2,apoptosis inhibitor 1,baculoviral IAP repeat-containing 2,cIAP1,hIAP-2,hIAP2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.