product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
F4/80
catalog :
70076
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D2S9R
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section
citations: 20
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 2b
Han H, Kim S, Kim Y, Jang S, Kwon Y, Choi D, et al. A novel role of CRTC2 in promoting nonalcoholic fatty liver disease. Mol Metab. 2022;55:101402 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:250; loading ...; fig 2f
Zhang M, Pan X, Fujiwara K, Jurcak N, Muth S, Zhou J, et al. Pancreatic cancer cells render tumor-associated macrophages metabolically reprogrammed by a GARP and DNA methylation-mediated mechanism. Signal Transduct Target Ther. 2021;6:366 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 6a
Choe D, Lee E, Beeghly Fadiel A, Wilson A, Whalen M, Adunyah S, et al. High-Fat Diet-Induced Obese Effects of Adipocyte-Specific CXCR2 Conditional Knockout in the Peritoneal Tumor Microenvironment of Ovarian Cancer. Cancers (Basel). 2021;13: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1g
Droho S, Cuda C, Perlman H, Lavine J. Macrophage-derived interleukin-6 is necessary and sufficient for choroidal angiogenesis. Sci Rep. 2021;11:18084 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 1d
Zheng Z, Li C, Shao G, Li J, Xu K, Zhao Z, et al. Hippo-YAP/MCP-1 mediated tubular maladaptive repair promote inflammation in renal failed recovery after ischemic AKI. Cell Death Dis. 2021;12:754 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 4a
Xu L, Zhang X, Xin Y, Ma J, Yang C, Zhang X, et al. Depdc5 deficiency exacerbates alcohol-induced hepatic steatosis via suppression of PPARα pathway. Cell Death Dis. 2021;12:710 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig s4a
Maier J, Rogg M, Helmstädter M, Sammarco A, Walz G, Werner M, et al. A Novel Model for Nephrotic Syndrome Reveals Associated Dysbiosis of the Gut Microbiome and Extramedullary Hematopoiesis. Cells. 2021;10: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3a, s3a, s4b
Ying L, Zhang M, Ma X, Si Y, Li X, Su J, et al. Macrophage LAMTOR1 Deficiency Prevents Dietary Obesity and Insulin Resistance Through Inflammation-Induced Energy Expenditure. Front Cell Dev Biol. 2021;9:672032 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; fig 3d
  • immunocytochemistry; mouse; 1:250; fig 2g
Kemp S, Carpenter E, Steele N, Donahue K, Nwosu Z, Pacheco A, et al. Apolipoprotein E Promotes Immune Suppression in Pancreatic Cancer through NF-κB-Mediated Production of CXCL1. Cancer Res. 2021;81:4305-4318 pubmed publisher
  • immunohistochemistry; mouse; 1:100; loading ...; fig 3g
Lindfors S, Polianskyte Prause Z, Bouslama R, Lehtonen E, Mannerla M, Nisen H, et al. Adiponectin receptor agonist AdipoRon ameliorates renal inflammation in diet-induced obese mice and endotoxin-treated human glomeruli ex vivo. Diabetologia. 2021;64:1866-1879 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 4a
Jang S, Economides K, Moniz R, Sia C, Lewis N, McCoy C, et al. ExoSTING, an extracellular vesicle loaded with STING agonists, promotes tumor immune surveillance. Commun Biol. 2021;4:497 pubmed publisher
  • immunohistochemistry; mouse; 1:200; loading ...; fig 3a
Zhang Z, Zhang N, Shi J, Dai C, Wu S, Jiao M, et al. Allograft or Recipient ST2 Deficiency Oppositely Affected Cardiac Allograft Vasculopathy via Differentially Altering Immune Cells Infiltration. Front Immunol. 2021;12:657803 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3f
Wang H, Huang J, Sue M, Ho W, Hsu Y, Chang K, et al. Interleukin-24 protects against liver injury in mouse models. EBioMedicine. 2021;64:103213 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig s2b
Hu J, Wang H, Li X, Liu Y, Mi Y, Kong H, et al. Fibrinogen-like protein 2 aggravates nonalcoholic steatohepatitis via interaction with TLR4, eliciting inflammation in macrophages and inducing hepatic lipid metabolism disorder. Theranostics. 2020;10:9702-9720 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 4b
Vasquez C, Mezzano V, Kessler N, Swardh F, Ernestad D, Mahoney V, et al. Connexin43 expression in bone marrow derived cells contributes to the electrophysiological properties of cardiac scar tissue. Sci Rep. 2020;10:2617 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:200; loading ...; fig 5c
Cai S, Ge M, Mennone A, Hoque R, Ouyang X, Boyer J. Inflammasome Is Activated in the Liver of Cholestatic Patients and Aggravates Hepatic Injury in Bile Duct-Ligated Mouse. Cell Mol Gastroenterol Hepatol. 2020;9:679-688 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig e8d
Aghajanian H, Kimura T, Rurik J, Hancock A, Leibowitz M, Li L, et al. Targeting cardiac fibrosis with engineered T cells. Nature. 2019;573:430-433 pubmed publisher
  • immunohistochemistry; mouse; 1:6000; loading ...; fig 5c
Zhang F, Parayath N, Ene C, Stephan S, Koehne A, Coon M, et al. Genetic programming of macrophages to perform anti-tumor functions using targeted mRNA nanocarriers. Nat Commun. 2019;10:3974 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig e5c
  • flow cytometry; mouse; loading ...; fig e5b
Yao W, Rose J, Wang W, Seth S, Jiang H, Taguchi A, et al. Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer. Nature. 2019;: pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 2h1
Sorrelle N, Ganguly D, Dominguez A, Zhang Y, Huang H, Dahal L, et al. Improved Multiplex Immunohistochemistry for Immune Microenvironment Evaluation of Mouse Formalin-Fixed, Paraffin-Embedded Tissues. J Immunol. 2019;202:292-299 pubmed publisher
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.