product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
EphA2 (D4A2) XP® Rabbit mAb
catalog :
6997
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D4A2
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation
more info or order :
Cell Signaling Technology product webpage
citations: 12
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig s6b
Enderle L, Shalaby K, Gorelik M, Weiss A, Blazer L, Paduch M, et al. A T cell redirection platform for co-targeting dual antigens on solid tumors. MAbs. 2021;13:1933690 pubmed publisher
  • western blot knockout validation; human; loading ...; fig 1a
  • immunocytochemistry; human; fig 2f
Zhang H, Li Y, Wang H, Zhang A, Chen M, Fang Z, et al. Ephrin receptor A2 is an epithelial cell receptor for Epstein-Barr virus entry. Nat Microbiol. 2018;3:1-8 pubmed publisher
  • western blot; human; loading ...; fig 1, 2
Leite M, Marques M, Melo J, Pinto M, Cavadas B, Aroso M, et al. Helicobacter Pylori Targets the EPHA2 Receptor Tyrosine Kinase in Gastric Cells Modulating Key Cellular Functions. Cells. 2020;9: pubmed publisher
  • western blot; human; loading ...; fig 3b
Hori A, Shimoda M, Naoi Y, Kagara N, Tanei T, Miyake T, et al. Vasculogenic mimicry is associated with trastuzumab resistance of HER2-positive breast cancer. Breast Cancer Res. 2019;21:88 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig e1f
Yao W, Rose J, Wang W, Seth S, Jiang H, Taguchi A, et al. Syndecan 1 is a critical mediator of macropinocytosis in pancreatic cancer. Nature. 2019;: pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; tbl 1
Gomes de Castro M, Hobartner C, Opazo F. Aptamers provide superior stainings of cellular receptors studied under super-resolution microscopy. PLoS ONE. 2017;12:e0173050 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 5b
  • western blot; human; loading ...; fig 5a
Kumar B, Dutta D, Iqbal J, Ansari M, Roy A, Chikoti L, et al. ESCRT-I Protein Tsg101 Plays a Role in the Post-macropinocytic Trafficking and Infection of Endothelial Cells by Kaposi's Sarcoma-Associated Herpesvirus. PLoS Pathog. 2016;12:e1005960 pubmed publisher
  • western blot; human; 1:100; fig st1
Treindl F, Ruprecht B, Beiter Y, Schultz S, Döttinger A, Staebler A, et al. A bead-based western for high-throughput cellular signal transduction analyses. Nat Commun. 2016;7:12852 pubmed publisher
  • immunohistochemistry - paraffin section; human; loading ...; fig 7
  • western blot; human; loading ...; fig 1a,2c
Eriksson O, Thulin A, Asplund A, Hegde G, Navani S, Siegbahn A. Cross-talk between the Tissue Factor/coagulation factor VIIa complex and the tyrosine kinase receptor EphA2 in cancer. BMC Cancer. 2016;16:341 pubmed publisher
  • western blot; human; 1:1000; fig 5
Liu X, Wang J, Li S, Li L, Huang M, Zhang Y, et al. Histone deacetylase 3 expression correlates with vasculogenic mimicry through the phosphoinositide3-kinase / ERK-MMP-laminin5γ2 signaling pathway. Cancer Sci. 2015;106:857-66 pubmed publisher
  • western blot; human
Eriksson O, Ramström M, Hörnaeus K, Bergquist J, Mokhtari D, Siegbahn A. The Eph tyrosine kinase receptors EphB2 and EphA2 are novel proteolytic substrates of tissue factor/coagulation factor VIIa. J Biol Chem. 2014;289:32379-91 pubmed publisher
  • western blot; human; 1:1000; fig s6
Lu H, Clauser K, Tam W, Fröse J, Ye X, Eaton E, et al. A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages. Nat Cell Biol. 2014;16:1105-17 pubmed publisher
product information
SKU :
6997P
Product-Name :
EphA2 (D4A2) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
RTK
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
125
Host :
Rabbit
Target :
EphA2
Primary-Protein :
EphA2
Alt-Names :
ARCC2,ECK,EPH receptor A2,EPHA2,Ephrin type-A receptor 2,Epithelial cell kinase,Tyrosine-protein kinase receptor ECK,ephrin receptor EphA2,epithelial cell receptor protein tyrosine kinase,protein tyrosine kinase,soluble EPHA2 variant 1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.