product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Merlin (D1D8) Rabbit mAb
catalog :
6995
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D1D8
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, western blot knockout validation, immunocytochemistry knockout validation
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry knockout validation; mouse; loading ...; fig 2d
  • western blot knockout validation; mouse; 1:750; loading ...; fig 2a
Fomicheva M, Macara I. Genome-wide CRISPR screen identifies noncanonical NF-κB signaling as a regulator of density-dependent proliferation. elife. 2020;9: pubmed publisher
  • immunocytochemistry; human; 1:400; loading ...; fig 3a
  • western blot; human; 1:2000; loading ...; fig 2a
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig s3a
Goswami S, Balasubramanian I, D Agostino L, Bandyopadhyay S, Patel R, Avasthi S, et al. RAB11A-mediated YAP localization to adherens and tight junctions is essential for colonic epithelial integrity. J Biol Chem. 2021;297:100848 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig st2
Adams C, Ercolano E, Ferluga S, Sofela A, Dave F, Negroni C, et al. A Rapid Robust Method for Subgrouping Non-NF2 Meningiomas According to Genotype and Detection of Lower Levels of M2 Macrophages in AKT1 E17K Mutated Tumours. Int J Mol Sci. 2020;21: pubmed publisher
  • immunocytochemistry; human; loading ...; fig 4i
Rausch V, Bostrom J, Park J, Bravo I, Feng Y, Hay D, et al. The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae. Curr Biol. 2019;29:242-255.e6 pubmed publisher
  • western blot; human; fig 1
Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher
  • western blot; human; fig 2
Chernova T, Sun X, Powley I, Galavotti S, Grosso S, Murphy F, et al. Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease. Cell Death Differ. 2016;23:1152-64 pubmed publisher
  • western blot; mouse; 1:1000; fig 3
Zoch A, Mayerl S, Schulz A, Greither T, Frappart L, Rübsam J, et al. Merlin Isoforms 1 and 2 Both Act as Tumour Suppressors and Are Required for Optimal Sperm Maturation. PLoS ONE. 2015;10:e0129151 pubmed publisher
  • western blot; mouse; 1:1000; fig s1
Chen S, Sanjana N, Zheng K, Shalem O, Lee K, Shi X, et al. Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. Cell. 2015;160:1246-60 pubmed publisher
  • western blot; human; fig 3
Moriarity B, Rahrmann E, Beckmann D, Conboy C, Watson A, Carlson D, et al. Simple and efficient methods for enrichment and isolation of endonuclease modified cells. PLoS ONE. 2014;9:e96114 pubmed publisher
  • western blot; human; loading ...; fig 1a
Tanaka I, Osada H, Fujii M, Fukatsu A, Hida T, Horio Y, et al. LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade. Oncogene. 2015;34:73-83 pubmed publisher
Nishigori K, Temma T, Onoe S, Sampei S, Kimura I, Ono M, et al. Development of a radioiodinated triazolopyrimidine probe for nuclear medical imaging of fatty acid binding protein 4. PLoS ONE. 2014;9:e94668 pubmed publisher
Takahashi A, Morita M, Yokoyama K, Suzuki T, Yamamoto T. Tob2 inhibits peroxisome proliferator-activated receptor ?2 expression by sequestering Smads and C/EBP? during adipocyte differentiation. Mol Cell Biol. 2012;32:5067-77 pubmed publisher
product information
SKU :
6995S
Product-Name :
Merlin (D1D8) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R
Applications :
Immunoprecipitation
Product-Category :
Neuroscience
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
70
Host :
Rabbit
Target :
Merlin
Primary-Protein :
merlin
Alt-Names :
ACN,BANF,MERL,Merlin,Moesin-ezrin-radixin-like protein,NF2,Neurofibromin-2,SCH,Schwannomerlin,Schwannomin,moesin-ezrin-radixin like,moesin-ezrin-radizin-like protein,neurofibromin 2,neurofibromin 2 (bilateral acoustic neuroma),neurofibromin 2 (merlin)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.