product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
TACE (D22H4) Rabbit mAb
catalog :
6978
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D22H4
reactivity :
human, mouse
application :
western blot, immunohistochemistry - frozen section
citations: 5
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3e, 5b
Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4b
Lu Y, Wan J, Yang Z, Lei X, Niu Q, Jiang L, et al. Regulated intramembrane proteolysis of the AXL receptor kinase generates an intracellular domain that localizes in the nucleus of cancer cells. FASEB J. 2017;31:1382-1397 pubmed publisher
  • western blot; human; 1:3000; loading ...; fig 3
Kneissl J, Hartmann A, Pfarr N, Erlmeier F, Lorber T, Keller S, et al. Influence of the HER receptor ligand system on sensitivity to cetuximab and trastuzumab in gastric cancer cell lines. J Cancer Res Clin Oncol. 2017;143:573-600 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...
Kuzmanov U, Guo H, Buchsbaum D, Cosme J, Abbasi C, Isserlin R, et al. Global phosphoproteomic profiling reveals perturbed signaling in a mouse model of dilated cardiomyopathy. Proc Natl Acad Sci U S A. 2016;113:12592-12597 pubmed
  • western blot; human; loading ...; fig 6a
Kaushik G, Venugopal A, Ramamoorthy P, Standing D, Subramaniam D, Umar S, et al. Honokiol inhibits melanoma stem cells by targeting notch signaling. Mol Carcinog. 2015;54:1710-21 pubmed publisher
product information
SKU :
6978S
Product-Name :
TACE (D22H4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H
Applications :
Western blot
Product-Category :
Developmental Biology
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
135
Host :
Rabbit
Target :
TACE
Primary-Protein :
TACE
Alt-Names :
ADA17,ADAM 17,ADAM metallopeptidase domain 17,ADAM metallopeptidase domain 18,ADAM17,ADAM18,CD156B,CSVP,Disintegrin and metalloproteinase domain-containing protein 17,MGC71942,Snake venom-like protease,TACE,TNF-alpha convertase,TNF-alpha converting enzyme,TNF-alpha-converting enzyme,tumor necrosis factor, alpha, converting enzyme
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.