product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Rab8 (D22D8) XP® Rabbit mAb
catalog :
6975
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D22D8
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig s2d
Shami Shah A, Batrouni A, Kim D, Punyala A, Cao W, Han C, et al. PLEKHA4/kramer Attenuates Dishevelled Ubiquitination to Modulate Wnt and Planar Cell Polarity Signaling. Cell Rep. 2019;27:2157-2170.e8 pubmed publisher
  • western blot; human; loading ...; fig 2e
Steger M, Diez F, Dhekne H, Lis P, Nirujogi R, Karayel Ö, et al. Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis. elife. 2017;6: pubmed publisher
  • western blot; mouse; loading ...; fig 6b
Gulbranson D, Davis E, Demmitt B, Ouyang Y, Ye Y, Yu H, et al. RABIF/MSS4 is a Rab-stabilizing holdase chaperone required for GLUT4 exocytosis. Proc Natl Acad Sci U S A. 2017;114:E8224-E8233 pubmed publisher
  • western blot; mouse; 1:5000; loading ...; fig 5f
Son S, Cha M, Choi H, Kang S, Choi H, Lee M, et al. Insulin-degrading enzyme secretion from astrocytes is mediated by an autophagy-based unconventional secretory pathway in Alzheimer disease. Autophagy. 2016;12:784-800 pubmed publisher
  • western blot; rat; 1:1000; fig 1
Stanic J, Carta M, Eberini I, Pelucchi S, Marcello E, Genazzani A, et al. Rabphilin 3A retains NMDA receptors at synaptic sites through interaction with GluN2A/PSD-95 complex. Nat Commun. 2015;6:10181 pubmed publisher
  • western blot; human
De Zio D, Molinari F, Rizza S, Gatta L, Ciotti M, Salvatore A, et al. Apaf1-deficient cortical neurons exhibit defects in axonal outgrowth. Cell Mol Life Sci. 2015;72:4173-91 pubmed publisher
  • immunocytochemistry; mouse
Lalioti V, Ilari A, O Connell D, Poser E, Sandoval I, Colotti G. Sorcin links calcium signaling to vesicle trafficking, regulates Polo-like kinase 1 and is necessary for mitosis. PLoS ONE. 2014;9:e85438 pubmed publisher
Alshafie W, Francis V, Bednarz K, Pan Y, Stroh T, McPherson P. Regulated resurfacing of a somatostatin receptor storage compartment fine-tunes pituitary secretion. J Cell Biol. 2020;219: pubmed publisher
Augustin H, McGourty K, Allen M, Adcott J, Wong C, Boucrot E, et al. Impact of insulin signaling and proteasomal activity on physiological output of a neuronal circuit in aging Drosophila melanogaster. Neurobiol Aging. 2018;66:149-157 pubmed publisher
Küchler P, Zimmermann G, Winzker M, Janning P, Waldmann H, Ziegler S. Identification of novel PDE? interacting proteins. Bioorg Med Chem. 2018;26:1426-1434 pubmed publisher
Court H, Ahearn I, Amoyel M, Bach E, Philips M. Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT. J Cell Biol. 2017;216:4165-4182 pubmed publisher
Esseltine J, Ribeiro F, Ferguson S. Rab8 modulates metabotropic glutamate receptor subtype 1 intracellular trafficking and signaling in a protein kinase C-dependent manner. J Neurosci. 2012;32:16933-42a pubmed publisher
product information
SKU :
6975P
Product-Name :
Rab8 (D22D8) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunofluorescence (Immunocytochemistry)
Product-Category :
Protein Folding and Trafficking
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
23
Host :
Rabbit
Target :
RAB8
Primary-Protein :
RAB8A
Alt-Names :
MEL,Oncogene c-mel,RAB8,RAB8A,RAB8A, member RAS oncogene family,Ras-related protein Rab-8A,mel transforming oncogene (RAB8 homolog),mel transforming oncogene (derived from cell line NK14),mel transforming oncogene (derived from cell line NK14)- RAB8 homolog,ras-associated protein RAB8
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.