product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-ULK1 (Ser757) Antibody
catalog :
6888S
quantity :
100 ul
price :
274 USD
clonality :
polyclonal
host :
rabbit
antigen modification :
phosphorylated
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 14
Published Application/Species/DilutionReference
  • western blot; human; 1:1000; fig 1
Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed publisher
  • western blot; mouse; fig 6
Cherepkova M, Sineva G, Pospelov V. Leukemia inhibitory factor (LIF) withdrawal activates mTOR signaling pathway in mouse embryonic stem cells through the MEK/ERK/TSC2 pathway. Cell Death Dis. 2016;7:e2050 pubmed publisher
  • western blot; mouse; fig 2
Liu D, Bordicchia M, Zhang C, Fang H, Wei W, Li J, et al. Activation of mTORC1 is essential for β-adrenergic stimulation of adipose browning. J Clin Invest. 2016;126:1704-16 pubmed publisher
  • western blot; human; fig 4
Rebsamen M, Pochini L, Stasyk T, de Araujo M, Galluccio M, Kandasamy R, et al. SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Nature. 2015;519:477-81 pubmed publisher
  • western blot; rat; fig s3
Wang J, Cao Y, Li Q, Yang Y, Jin M, Chen D, et al. A pivotal role of FOS-mediated BECN1/Beclin 1 upregulation in dopamine D2 and D3 receptor agonist-induced autophagy activation. Autophagy. 2015;11:2057-2073 pubmed
  • western blot; rat; 1:1000; fig 3e
Zhang J, Tripathi D, Jing J, Alexander A, Kim J, Powell R, et al. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015;17:1259-69 pubmed publisher
  • western blot; mouse; fig 4
Feng D, Youn D, Zhao X, Gao Y, Quinn W, Xiaoli A, et al. mTORC1 Down-Regulates Cyclin-Dependent Kinase 8 (CDK8) and Cyclin C (CycC). PLoS ONE. 2015;10:e0126240 pubmed publisher
  • western blot; human; 1:1000; fig 6
Medina D, Di Paola S, Peluso I, Armani A, De Stefani D, Venditti R, et al. Lysosomal calcium signalling regulates autophagy through calcineurin and ​TFEB. Nat Cell Biol. 2015;17:288-99 pubmed
  • western blot; human; 1:1000
Li C, Siragy H. (Pro)renin receptor regulates autophagy and apoptosis in podocytes exposed to high glucose. Am J Physiol Endocrinol Metab. 2015;309:E302-10 pubmed publisher
  • western blot; human; fig 3a
  • western blot; mouse; fig 3a
Munson M, Allen G, Toth R, Campbell D, Lucocq J, Ganley I. mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival. EMBO J. 2015;34:2272-90 pubmed publisher
  • western blot; mouse
  • western blot; rat
Jaishy B, Zhang Q, Chung H, Riehle C, Soto J, Jenkins S, et al. Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity. J Lipid Res. 2015;56:546-61 pubmed publisher
  • immunocytochemistry; mouse; 1:100
Bandyopadhyay U, Nagy M, Fenton W, Horwich A. Absence of lipofuscin in motor neurons of SOD1-linked ALS mice. Proc Natl Acad Sci U S A. 2014;111:11055-60 pubmed publisher
  • western blot; human; fig 4
Chin R, Fu X, Pai M, Vergnes L, Hwang H, Deng G, et al. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature. 2014;510:397-401 pubmed publisher
  • western blot; mouse; fig 6
Watanabe T, Takemura G, Kanamori H, Goto K, Tsujimoto A, Okada H, et al. Restriction of food intake prevents postinfarction heart failure by enhancing autophagy in the surviving cardiomyocytes. Am J Pathol. 2014;184:1384-94 pubmed publisher
product information
SKU :
6888S
Product-Name :
Phospho-ULK1 (Ser757) Antibody
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, Mk
Applications :
Western blot
Product-Category :
Autophagy
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Polyclonal Antibody
MW :
140
Host :
Rabbit
Target :
ULK1 (Ser758) phosphate
Primary-Protein :
ULK1
Alt-Names :
ATG1,ATG1 autophagy related 1 homolog,FLJ38455,FLJ46475,KIAA0722,Serine/threonine-protein kinase ULK1,ULK1,UNC51,Unc-51-like kinase 1,Unc51.1,unc-51-like kinase 1 (C. elegans)
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.