product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
PARP (46D11) Rabbit mAb (Sepharose Bead Conjugate)
catalog :
6704
clonality :
monoclonal
host :
domestic rabbit
conjugate :
Bead
clone name :
46D11
reactivity :
human, mouse, rat
application :
immunoprecipitation
more info or order :
Cell Signaling Technology product webpage
citations: 19
Reference
Cui Y, Sun Y, Hu S, Luo J, Li L, Li X, et al. Neuroendocrine prostate cancer (NEPCa) increased the neighboring PCa chemoresistance via altering the PTHrP/p38/Hsp27/androgen receptor (AR)/p21 signals. Oncogene. 2016;35:6065-6076 pubmed publisher
Harada N, Katsuki T, Takahashi Y, Masuda T, Yoshinaga M, Adachi T, et al. Androgen receptor silences thioredoxin-interacting protein and competitively inhibits glucocorticoid receptor-mediated apoptosis in pancreatic β-Cells. J Cell Biochem. 2015;116:998-1006 pubmed publisher
Lu K, Fang X, Feng L, Jiang Y, Zhou X, Liu X, et al. The STAT3 inhibitor WP1066 reverses the resistance of chronic lymphocytic leukemia cells to histone deacetylase inhibitors induced by interleukin-6. Cancer Lett. 2015;359:250-8 pubmed publisher
Kung C, Khaku S, Jennis M, Zhou Y, Murphy M. Identification of TRIML2, a novel p53 target, that enhances p53 SUMOylation and regulates the transactivation of proapoptotic genes. Mol Cancer Res. 2015;13:250-62 pubmed publisher
Momose I, Abe H, Watanabe T, Ohba S, Yamazaki K, Dan S, et al. Antitumor effects of tyropeptin-boronic acid derivatives: New proteasome inhibitors. Cancer Sci. 2014;105:1609-15 pubmed publisher
Soderquist R, Danilov A, Eastman A. Gossypol increases expression of the pro-apoptotic BH3-only protein NOXA through a novel mechanism involving phospholipase A2, cytoplasmic calcium, and endoplasmic reticulum stress. J Biol Chem. 2014;289:16190-9 pubmed publisher
Yang D, Meng X, Xue B, Liu N, Wang X, Zhu H. MiR-942 mediates hepatitis C virus-induced apoptosis via regulation of ISG12a. PLoS ONE. 2014;9:e94501 pubmed publisher
Singh R, Shankar B, Sainis K. TGF-?1-ROS-ATM-CREB signaling axis in macrophage mediated migration of human breast cancer MCF7 cells. Cell Signal. 2014;26:1604-15 pubmed publisher
Bhattacharyya S, Ghosh S, Sil P. Amelioration of aspirin induced oxidative impairment and apoptotic cell death by a novel antioxidant protein molecule isolated from the herb Phyllanthus niruri. PLoS ONE. 2014;9:e89026 pubmed publisher
Erttmann S, Gekara N, Fallman M. Bacteria induce prolonged PMN survival via a phosphatidylcholine-specific phospholipase C- and protein kinase C-dependent mechanism. PLoS ONE. 2014;9:e87859 pubmed publisher
Matthess Y, Raab M, Knecht R, Becker S, Strebhardt K. Sequential Cdk1 and Plk1 phosphorylation of caspase-8 triggers apoptotic cell death during mitosis. Mol Oncol. 2014;8:596-608 pubmed publisher
Soderquist R, Pletnev A, Danilov A, Eastman A. The putative BH3 mimetic S1 sensitizes leukemia to ABT-737 by increasing reactive oxygen species, inducing endoplasmic reticulum stress, and upregulating the BH3-only protein NOXA. Apoptosis. 2014;19:201-9 pubmed publisher
Amengual J, Clark Garvey S, Kalac M, Scotto L, Marchi E, Neylon E, et al. Sirtuin and pan-class I/II deacetylase (DAC) inhibition is synergistic in preclinical models and clinical studies of lymphoma. Blood. 2013;122:2104-13 pubmed publisher
Cai Y, Cui W, Chen W, Wei P, Chi Y, Zhang P, et al. The effects of a histone deacetylase inhibitor on biological behavior of diffuse large B-cell lymphoma cell lines and insights into the underlying mechanisms. Cancer Cell Int. 2013;13:57 pubmed publisher
Fedorchenko O, Stiefelhagen M, Peer Zada A, Barthel R, Mayer P, Eckei L, et al. CD44 regulates the apoptotic response and promotes disease development in chronic lymphocytic leukemia. Blood. 2013;121:4126-36 pubmed publisher
Liu C, Wu J, Paudyal S, You Z, Yu X. CHFR is important for the first wave of ubiquitination at DNA damage sites. Nucleic Acids Res. 2013;41:1698-710 pubmed publisher
Niegisch G, Knievel J, Koch A, Hader C, Fischer U, Albers P, et al. Changes in histone deacetylase (HDAC) expression patterns and activity of HDAC inhibitors in urothelial cancers. Urol Oncol. 2013;31:1770-9 pubmed publisher
Covy J, Waxman E, Giasson B. Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants. J Neurosci Res. 2012;90:2306-16 pubmed publisher
Zhang Y, Li X, Huang Z, Zheng W, Fan C, Chen T. Enhancement of cell permeabilization apoptosis-inducing activity of selenium nanoparticles by ATP surface decoration. Nanomedicine. 2013;9:74-84 pubmed publisher
product information
SKU :
6704S
Product-Name :
PARP (46D11) Rabbit mAb (Sepharose Bead Conjugate)
Size :
400 ul
Price-(USD) :
291 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Immunoprecipitation
Product-Category :
Apoptosis
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
116, 89
Host :
Rabbit
Target :
PARP1 (Asp214, 89 kD) cleaved
Primary-Protein :
PARP1
Alt-Names :
ADP-ribosyltransferase (NAD+,ADP-ribosyltransferase NAD(+),ADPRT,ADPRT 1,ADPRT1,NAD(+) ADP-ribosyltransferase 1,PARP,PARP-1,PARP1,PPOL,Poly [ADP-ribose] polymerase 1,Poly[ADP-ribose] synthase 1,pADPRT-1,poly (ADP-ribose) polymerase 1,poly (ADP-ribose) polymerase family, member 1,poly (ADP-ribose) polymerase),poly(ADP-ribose) polymerase,poly(ADP-ribose) synthetase,poly(ADP-ribosyl)transferase
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.