product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
CHD7 (D3F5) Rabbit mAb
catalog :
6505
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D3F5
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - paraffin section, ChIP-Seq, western blot knockout validation, immunohistochemistry knockout validation
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; 1:2000; fig s1b
  • western blot knockout validation; mouse; 1:1000; fig s1c
Reddy N, Majidi S, Kong L, Nemera M, Ferguson C, Moore M, et al. CHARGE syndrome protein CHD7 regulates epigenomic activation of enhancers in granule cell precursors and gyrification of the cerebellum. Nat Commun. 2021;12:5702 pubmed publisher
  • western blot; human; 1:400; loading ...; fig 5c
  • immunohistochemistry knockout validation; mouse; 1:400; loading ...; fig s3a
  • ChIP-Seq; mouse; loading ...; fig 4e
  • immunohistochemistry - paraffin section; mouse; 1:400; loading ...; fig 1a
Feng W, Kawauchi D, Körkel Qu H, Deng H, Serger E, Sieber L, et al. Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme. Nat Commun. 2017;8:14758 pubmed publisher
  • chromatin immunoprecipitation; human; fig 4b
Jamadagni P, Breuer M, Schmeisser K, Cardinal T, Kassa B, Parker J, et al. Chromatin remodeller CHD7 is required for GABAergic neuron development by promoting PAQR3 expression. EMBO Rep. 2021;22:e50958 pubmed publisher
  • ChIP-Seq; mouse; loading ...; fig 1i
  • western blot; mouse; loading ...; fig 1g
Zhao C, Dong C, Frah M, Deng Y, Marie C, Zhang F, et al. Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair. Dev Cell. 2018;45:753-768.e8 pubmed publisher
  • western blot; human; loading ...; fig 2c
Lee B, Stallcup M. Glucocorticoid receptor binding to chromatin is selectively controlled by the coregulator Hic-5 and chromatin remodeling enzymes. J Biol Chem. 2017;292:9320-9334 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 6e
Bird J, Barzik M, Drummond M, Sutton D, Goodman S, Morozko E, et al. Harnessing molecular motors for nanoscale pulldown in live cells. Mol Biol Cell. 2017;28:463-475 pubmed publisher
  • ChIP-Seq; mouse; fig 1a
He D, Marie C, Zhao C, Kim B, Wang J, Deng Y, et al. Chd7 cooperates with Sox10 and regulates the onset of CNS myelination and remyelination. Nat Neurosci. 2016;19:678-89 pubmed publisher
Doi T, Ogata T, Yamauchi J, Sawada Y, Tanaka S, Nagao M. Chd7 Collaborates with Sox2 to Regulate Activation of Oligodendrocyte Precursor Cells after Spinal Cord Injury. J Neurosci. 2017;37:10290-10309 pubmed publisher
product information
SKU :
6505S
Product-Name :
CHD7 (D3F5) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M
Applications :
Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
336
Host :
Rabbit
Target :
CHD7
Primary-Protein :
CHD-7
Alt-Names :
ATP-dependent helicase CHD7,CHD-7,CHD7,Chromodomain-helicase-DNA-binding protein 7,FLJ20357,FLJ20361,IS3,KAL5,KIAA1416,chromodomain helicase DNA binding protein 7,chromodomain helicase DNA binding protein 7 isoform CRA_e
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.