product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-DRP1 (Ser637) (D3A4) Rabbit mAb
catalog :
6319
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
antigen modification :
phosphorylated
clone name :
D3A4
reactivity :
human, mouse, rat, fruit fly
application :
western blot, immunocytochemistry, immunohistochemistry - paraffin section
citations: 7
Published Application/Species/Sample/DilutionReference
  • western blot; fruit fly; loading ...; fig 4h
Anding A, Wang C, Chang T, Sliter D, Powers C, Hofmann K, et al. Vps13D Encodes a Ubiquitin-Binding Protein that Is Required for the Regulation of Mitochondrial Size and Clearance. Curr Biol. 2018;28:287-295.e6 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig s3e
Dai S, Dulcey A, Hu X, Wassif C, Porter F, Austin C, et al. Methyl-β-cyclodextrin restores impaired autophagy flux in Niemann-Pick C1-deficient cells through activation of AMPK. Autophagy. 2017;13:1435-1451 pubmed publisher
  • western blot; rat; fig 1f
Monterisi S, Lobo M, Livie C, Castle J, Weinberger M, Baillie G, et al. PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling. elife. 2017;6: pubmed publisher
  • western blot; human; loading ...; fig 3d
Janer A, Prudent J, Paupe V, Fahiminiya S, Majewski J, Sgarioto N, et al. SLC25A46 is required for mitochondrial lipid homeostasis and cristae maintenance and is responsible for Leigh syndrome. EMBO Mol Med. 2016;8:1019-38 pubmed publisher
  • western blot; mouse
Picard M, Azuelos I, Jung B, Giordano C, Matecki S, Hussain S, et al. Mechanical ventilation triggers abnormal mitochondrial dynamics and morphology in the diaphragm. J Appl Physiol (1985). 2015;118:1161-71 pubmed publisher
  • immunohistochemistry - paraffin section; human; fig 8
  • immunocytochemistry; human; fig 2
  • western blot; human; fig 2
Xie Q, Wu Q, Horbinski C, Flavahan W, Yang K, Zhou W, et al. Mitochondrial control by DRP1 in brain tumor initiating cells. Nat Neurosci. 2015;18:501-10 pubmed publisher
Liu Z, Chen X, Song H, Wang H, Zhang G, Wang H, et al. Snail regulated by PKC/GSK-3? pathway is crucial for EGF-induced epithelial-mesenchymal transition (EMT) of cancer cells. Cell Tissue Res. 2014;358:491-502 pubmed publisher
product information
SKU :
6319S
Product-Name :
Phospho-DRP1 (Ser637) (D3A4) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
R, (H, M, Mk)
Applications :
Western blot
Product-Category :
Cytoskeletal Signaling
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
78-82
Host :
Rabbit
Target :
DRP1 (Ser637) phosphate
Primary-Protein :
DRP1
Alt-Names :
DLP1,DNM1L,DRP1,DVLP,DYNIV-11,Dnm1p/Vps1p-like protein,Dymple,Dynamin family member proline-rich carboxyl-terminal domain less,Dynamin-1-like protein,Dynamin-like protein,Dynamin-like protein 4,Dynamin-like protein IV,Dynamin-related protein 1,FLJ41912,HdynIV,VPS1,dynamin 1-like
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.