LATS2 (D83D6) Rabbit mAb | Cell Signaling Technology 5888 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

LATS2 (D83D6) Rabbit mAb

catalog :

5888

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D83D6

reactivity :

human, mouse

application :

western blot, western blot knockout validation

more info or order :

Cell Signaling Technology product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; loading ...; fig s3a western blot; human; loading ...; fig s2c	Yuan T, Annamalai K, Naik S, Lupse B, Geravandi S, Pal A, et al. The Hippo kinase LATS2 impairs pancreatic β-cell survival in diabetes through the mTORC1-autophagy axis. Nat Commun. 2021;12:4928 pubmed publisher
western blot; human; loading ...; fig 4g	Zhang Y, He L, Huang L, Yao S, Lin N, Li P, et al. Oncogenic PAX6 elicits CDK4/6 inhibitor resistance by epigenetically inactivating the LATS2-Hippo signaling pathway. Clin Transl Med. 2021;11:e503 pubmed publisher
western blot; human; loading ...; fig 6e	Yin L, Li W, Xu A, Shi H, Wang K, Yang H, et al. SH3BGRL2 inhibits growth and metastasis in clear cell renal cell carcinoma via activating hippo/TEAD1-Twist1 pathway. EBioMedicine. 2020;51:102596 pubmed publisher
western blot; human; loading ...; fig 1f	Rausch V, Bostrom J, Park J, Bravo I, Feng Y, Hay D, et al. The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae. Curr Biol. 2019;29:242-255.e6 pubmed publisher
western blot; mouse; loading ...; fig 2b	Pan W, Moroishi T, Koo J, Guan K. Cell type-dependent function of LATS1/2 in cancer cell growth. Oncogene. 2019;38:2595-2610 pubmed publisher
western blot; human; loading ...; fig 1c	Peng C, Zhu Y, Zhang W, Liao Q, Chen Y, Zhao X, et al. Regulation of the Hippo-YAP Pathway by Glucose Sensor O-GlcNAcylation. Mol Cell. 2017;68:591-604.e5 pubmed publisher
western blot; human; fig 5	Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;291:14761-72 pubmed publisher
western blot; human; fig 3	Kim M, Kim M, Park S, Lee C, Lim D. Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition. EMBO Rep. 2016;17:64-78 pubmed publisher
western blot; human; 1:1000; fig 1	Meng Z, Moroishi T, Mottier Pavie V, Plouffe S, Hansen C, Hong A, et al. MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway. Nat Commun. 2015;6:8357 pubmed publisher
western blot; human; fig 3	Kim M, Kim M, Lee M, Kim C, Lim D. The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis. Nat Commun. 2014;5:5370 pubmed publisher
	Seo E, Kim W, Hur J, Kim H, Nam S, Choi A, et al. The Hippo-Salvador signaling pathway regulates renal tubulointerstitial fibrosis. Sci Rep. 2016;6:31931 pubmed publisher

product information

SKU :

5888S

Product-Name :

LATS2 (D83D6) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, (Mk)

Applications :

Western blot

Product-Category :

Cell Cycle / Checkpoint Control

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

150

Host :

Rabbit

Target :

LATS2

Primary-Protein :

LATS2

Alt-Names :

FLJ13161,KPM,Kinase phosphorylated during mitosis protein,LATS (large tumor suppressor, Drosophila) homolog 2,LATS, large tumor suppressor, homolog 2 (Drosophila),LATS2,Large tumor suppressor homolog 2,Serine/threonine-protein kinase LATS2,Serine/threonine-protein kinase kpm,Warts-like kinase,serine/threonine kinase KPM

more info or order :

Cell Signaling Technology product webpage