product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Phospho-ULK1 (Ser555) (D1H4) Rabbit mAb
catalog :
5869S
quantity :
100 ul
price :
274 USD
clonality :
monoclonal
host :
rabbit
antigen modification :
phosphorylated
clone name :
D1H4

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation
citations: 11
Published Application/Species/DilutionReference
  • western blot; mouse; 1:1000; fig 4
Lesmana R, Sinha R, Singh B, Zhou J, Ohba K, Wu Y, et al. Thyroid Hormone Stimulation of Autophagy Is Essential for Mitochondrial Biogenesis and Activity in Skeletal Muscle. Endocrinology. 2016;157:23-38 pubmed publisher
  • western blot; mouse; fig 6
Cherepkova M, Sineva G, Pospelov V. Leukemia inhibitory factor (LIF) withdrawal activates mTOR signaling pathway in mouse embryonic stem cells through the MEK/ERK/TSC2 pathway. Cell Death Dis. 2016;7:e2050 pubmed publisher
  • western blot; rat; 1:1000
Harris-White M, Ferbas K, Johnson M, Eslami P, Poteshkina A, Venkova K, et al. A cell-penetrating ester of the neural metabolite lanthionine ketimine stimulates autophagy through the mTORC1 pathway: Evidence for a mechanism of action with pharmacological implications for neurodegenerative pathologies. Neurobiol Dis. 2015;84:60-8 pubmed publisher
  • western blot; mouse
Fukui K, Ferris H, Kahn C. Effect of cholesterol reduction on receptor signaling in neurons. J Biol Chem. 2015;290:26383-92 pubmed publisher
  • western blot; mouse
  • western blot; rat
Jaishy B, Zhang Q, Chung H, Riehle C, Soto J, Jenkins S, et al. Lipid-induced NOX2 activation inhibits autophagic flux by impairing lysosomal enzyme activity. J Lipid Res. 2015;56:546-61 pubmed publisher
  • western blot; human; fig 7
Kemp M, Lindsey-Boltz L, Sancar A. UV Light Potentiates STING (Stimulator of Interferon Genes)-dependent Innate Immune Signaling through Deregulation of ULK1 (Unc51-like Kinase 1). J Biol Chem. 2015;290:12184-94 pubmed publisher
  • western blot; human
  • western blot; mouse
  • immunoprecipitation; human
  • immunoprecipitation; mouse
  • immunocytochemistry; human
  • immunocytochemistry; mouse
Ro S, Semple I, Park H, Park H, Park H, Kim M, et al. Sestrin2 promotes Unc-51-like kinase 1 mediated phosphorylation of p62/sequestosome-1. FEBS J. 2014;281:3816-27 pubmed publisher
  • western blot; mouse
Ost M, Werner F, Dokas J, Klaus S, Voigt A. Activation of AMPKα2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity. PLoS ONE. 2014;9:e94689 pubmed publisher
Weikel K, Cacicedo J, Ruderman N, Ido Y. Glucose and palmitate uncouple AMPK from autophagy in human aortic endothelial cells. Am J Physiol Cell Physiol. 2015;308:C249-63 pubmed publisher
Stellrecht C, Vangapandu H, Le X, Mao W, Shentu S. ATP directed agent, 8-chloro-adenosine, induces AMP activated protein kinase activity, leading to autophagic cell death in breast cancer cells. J Hematol Oncol. 2014;7:23 pubmed publisher
Wen H, Gris D, Lei Y, JHA S, Zhang L, Huang M, et al. Fatty acid-induced NLRP3-ASC inflammasome activation interferes with insulin signaling. Nat Immunol. 2011;12:408-15 pubmed publisher
product information
SKU :
5869S
Product-Name :
Phospho-ULK1 (Ser555) (D1H4) Rabbit mAb
Size :
100 ul
Price-(USD) :
274 USD
Species-x-Reactivity :
H, M, (R)
Applications :
Immunoprecipitation
Product-Category :
Autophagy
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
140
Host :
Rabbit
Target :
ULK1 (Ser556) phosphate
Primary-Protein :
ULK1
Alt-Names :
ATG1,ATG1 autophagy related 1 homolog,FLJ38455,FLJ46475,KIAA0722,Serine/threonine-protein kinase ULK1,ULK1,UNC51,Unc-51-like kinase 1,Unc51.1,unc-51-like kinase 1 (C. elegans)
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.