product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
NFAT1 (D43B1) XP® Rabbit mAb
catalog :
5861
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D43B1
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:100; fig 5e
von Moltke J, O Leary C, Barrett N, Kanaoka Y, Austen K, Locksley R. Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. J Exp Med. 2017;214:27-37 pubmed publisher
  • western blot; mouse; loading ...
Keller M, Paul P, Rabaglia M, Stapleton D, Schueler K, Broman A, et al. The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets. PLoS Genet. 2016;12:e1006466 pubmed publisher
  • western blot; mouse; fig 5
Freedman T, Tan Y, Skrzypczynska K, Manz B, Sjaastad F, Goodridge H, et al. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. elife. 2015;4: pubmed publisher
  • western blot; human; 1:500; fig 5a &i
SCANLON C, Banerjee R, Inglehart R, Liu M, Russo N, Hariharan A, et al. Galanin modulates the neural niche to favour perineural invasion in head and neck cancer. Nat Commun. 2015;6:6885 pubmed publisher
  • immunocytochemistry; mouse; 1:20; fig 5d
  • western blot; mouse; 1:1000; fig 5c
Herbst S, Shah A, Mazon Moya M, Marzola V, Jensen B, Reed A, et al. Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. EMBO Mol Med. 2015;7:240-58 pubmed publisher
Bray C, Wright D, Haupt S, Thomas S, Stauss H, Zamoyska R. Crispr/Cas Mediated Deletion of PTPN22 in Jurkat T Cells Enhances TCR Signaling and Production of IL-2. Front Immunol. 2018;9:2595 pubmed publisher
Cuadrado E, van den Biggelaar M, de Kivit S, Chen Y, Slot M, Doubal I, et al. Proteomic Analyses of Human Regulatory T Cells Reveal Adaptations in Signaling Pathways that Protect Cellular Identity. Immunity. 2018;48:1046-1059.e6 pubmed publisher
Marangoni F, Zhang R, Mani V, Thelen M, Ali Akbar N, Warner R, et al. Tumor Tolerance-Promoting Function of Regulatory T Cells Is Optimized by CD28, but Strictly Dependent on Calcineurin. J Immunol. 2018;200:3647-3661 pubmed publisher
Zhang W, Takahara T, Achiha T, Shibata H, Maki M. Nanoluciferase Reporter Gene System Directed by Tandemly Repeated Pseudo-Palindromic NFAT-Response Elements Facilitates Analysis of Biological Endpoint Effects of Cellular Ca2+ Mobilization. Int J Mol Sci. 2018;19: pubmed publisher
Leoni C, Montagner S, Rinaldi A, Bertoni F, Polletti S, Balestrieri C, et al. Dnmt3a restrains mast cell inflammatory responses. Proc Natl Acad Sci U S A. 2017;114:E1490-E1499 pubmed publisher
García Faroldi G, Melo F, Bruemmer D, Conneely O, Pejler G, Lundequist A. Nuclear receptor 4a3 (nr4a3) regulates murine mast cell responses and granule content. PLoS ONE. 2014;9:e89311 pubmed publisher
Fu G, Casas J, Rigaud S, Rybakin V, Lambolez F, Brzostek J, et al. Themis sets the signal threshold for positive and negative selection in T-cell development. Nature. 2013;504:441-5 pubmed publisher
product information
SKU :
5861P
Product-Name :
NFAT1 (D43B1) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, M
Applications :
Flow cytometry
Product-Category :
Immunology and Inflammation
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
140
Host :
Rabbit
Target :
NFAT1
Primary-Protein :
NFAT1
Alt-Names :
NF-ATc2,NF-ATp,NFAC2,NFAT pre-existing subunit,NFAT transcription complex, preexisting component,NFAT1,NFATC2,NFATP,Nuclear factor of activated T-cells, cytoplasmic 2,T cell transcription factor NFAT1,T-cell transcription factor NFAT1,nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2,nuclear factor of activated T-cells, preexisting component,preexisting nuclear factor of activated T-cells 2
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.