product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Bmi1 (D42B3) Rabbit mAb
catalog :
5856
clonality :
monoclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
D42B3
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - frozen section
more info or order :
Cell Signaling Technology product webpage
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3a
Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed publisher
  • western blot; human; loading ...; fig 1d
Wheaton K, Sarkari F, Stanly Johns B, Davarinejad H, Egorova O, Kaustov L, et al. UbE2E1/UBCH6 Is a Critical in Vivo E2 for the PRC1-catalyzed Ubiquitination of H2A at Lys-119. J Biol Chem. 2017;292:2893-2902 pubmed publisher
  • western blot; human; fig 6
  • western blot; mouse; fig 5
Lee S, Litan A, Li Z, Graves B, Lindsey S, Barwe S, et al. Na,K-ATPase β1-subunit is a target of sonic hedgehog signaling and enhances medulloblastoma tumorigenicity. Mol Cancer. 2015;14:159 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 3
  • chromatin immunoprecipitation; mouse; fig 2
  • western blot; mouse; fig 2
Yamakoshi K, Katano S, Iida M, Kimura H, Okuma A, Ikemoto Uezumi M, et al. Dysregulation of the Bmi-1/p16(Ink⁴a) pathway provokes an aging-associated decline of submandibular gland function. Aging Cell. 2015;14:616-24 pubmed publisher
Zhang X, Guo W, Wang X, Liu X, Huang M, Gan L, et al. Antitumor activity and inhibitory effects on cancer stem cell-like properties of Adeno-associated virus (AAV) -mediated Bmi-1 interference driven by Bmi-1 promoter for gastric cancer. Oncotarget. 2016;7:22733-45 pubmed publisher
Wang T, Chen T, Niu H, Li C, Xu C, Li Y, et al. MicroRNA-218 inhibits the proliferation and metastasis of esophageal squamous cell carcinoma cells by targeting BMI1. Int J Mol Med. 2015;36:93-102 pubmed publisher
product information
SKU :
5856S
Product-Name :
Bmi1 (D42B3) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, R, Mk
Applications :
Chromatin Immunoprecipitation
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
41, 43
Host :
Rabbit
Target :
BMI1
Primary-Protein :
BMI1
Alt-Names :
B lymphoma Mo-MLV insertion region 1 homolog,BMI1,BMI1 polycomb ring finger oncogene,MGC12685,PCGF4,Polycomb complex protein BMI-1,Polycomb group RING finger protein 4,RING finger protein 51,RNF51,flvi-2/bmi-1,murine leukemia viral (bmi-1) oncogene homolog,oncogene BMI-1,polycomb group protein Bmi1,polycomb group ring finger 4
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.