product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
GATA-3 (D13C9) XP® Rabbit mAb
catalog :
5852
clonality :
monoclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
D13C9
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, chromatin immunoprecipitation, immunohistochemistry - paraffin section, ChIP-Seq, immunohistochemistry knockout validation
citations: 19
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; human; 1:100; fig s1e
  • ChIP-Seq; human; 1:400; loading ...; fig s2c
  • immunohistochemistry - paraffin section; human; 1:100; loading ...; fig 1c, 1d
  • chromatin immunoprecipitation; human; 1:400; loading ...; fig 2c, 2f, 6f
Geng X, Wang C, Gao X, Chowdhury P, Weiss J, Villegas J, et al. GATA-3 is a proto-oncogene in T-cell lymphoproliferative neoplasms. Blood Cancer J. 2022;12:149 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5j
Cortes J, Filip I, Albero R, Patiño Galindo J, Quinn S, Lin W, et al. Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma. Cell Rep. 2022;39:110695 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 2j
Han D, Wu G, Chen R, Drexler H, MacCarthy C, Kim K, et al. A balanced Oct4 interactome is crucial for maintaining pluripotency. Sci Adv. 2022;8:eabe4375 pubmed publisher
  • immunohistochemistry; mouse; 1:500; loading ...; fig 2e
He B, Chen P, Zambrano S, Dabaghie D, Hu Y, Möller Hackbarth K, et al. Single-cell RNA sequencing reveals the mesangial identity and species diversity of glomerular cell transcriptomes. Nat Commun. 2021;12:2141 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 2h
Sripada A, Sirohi K, Michalec L, Guo L, McKay J, Yadav S, et al. Sprouty2 positively regulates T cell function and airway inflammation through regulation of CSK and LCK kinases. PLoS Biol. 2021;19:e3001063 pubmed publisher
  • ChIP-Seq; human; loading ...; fig 5a
  • chromatin immunoprecipitation; human; loading ...; fig 5d
  • immunoprecipitation; human; loading ...; fig 2c
  • western blot; human; loading ...; fig 5e
Yu W, Huang W, Yang Y, Qiu R, Zeng Y, Hou Y, et al. GATA3 recruits UTX for gene transcriptional activation to suppress metastasis of breast cancer. Cell Death Dis. 2019;10:832 pubmed publisher
  • western blot; human; fig 1b
van Groningen T, Koster J, Valentijn L, Zwijnenburg D, Akogul N, Hasselt N, et al. Neuroblastoma is composed of two super-enhancer-associated differentiation states. Nat Genet. 2017;49:1261-1266 pubmed publisher
  • immunocytochemistry; human; 1:100; fig s2
  • western blot; human; 1:1000; fig 3
Mair B, Konopka T, Kerzendorfer C, Sleiman K, Salic S, Serra V, et al. Gain- and Loss-of-Function Mutations in the Breast Cancer Gene GATA3 Result in Differential Drug Sensitivity. PLoS Genet. 2016;12:e1006279 pubmed publisher
  • immunohistochemistry; mouse; fig 2
Xiao L, Feng Q, Zhang Z, Wang F, Lydon J, Ittmann M, et al. The essential role of GATA transcription factors in adult murine prostate. Oncotarget. 2016;7:47891-47903 pubmed publisher
  • chromatin immunoprecipitation; human
  • western blot; human
Kao S, Stankovic K. Transactivation of human osteoprotegerin promoter by GATA-3. Sci Rep. 2015;5:12479 pubmed publisher
  • immunohistochemistry; human; fig 5
Eriksson P, Aine M, Veerla S, Liedberg F, Sjödahl G, Höglund M. Molecular subtypes of urothelial carcinoma are defined by specific gene regulatory systems. BMC Med Genomics. 2015;8:25 pubmed publisher
  • immunohistochemistry - paraffin section; human; 1:1000; tbl 2
Weissferdt A, Rodriguez Canales J, Liu H, Fujimoto J, Wistuba I, Moran C. Primary mediastinal seminomas: a comprehensive immunohistochemical study with a focus on novel markers. Hum Pathol. 2015;46:376-83 pubmed publisher
  • immunocytochemistry; human
  • western blot; human
Adomas A, Grimm S, Malone C, Takaku M, Sims J, Wade P. Breast tumor specific mutation in GATA3 affects physiological mechanisms regulating transcription factor turnover. BMC Cancer. 2014;14:278 pubmed publisher
Baker S, Arlt V, Indra R, Joel M, Stiborova M, Eardley I, et al. Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of "luminal" muscle-invasive bladder cancers. Mol Carcinog. 2018;57:606-618 pubmed publisher
Boeva V, Louis Brennetot C, Peltier A, Durand S, Pierre Eugène C, Raynal V, et al. Heterogeneity of neuroblastoma cell identity defined by transcriptional circuitries. Nat Genet. 2017;49:1408-1413 pubmed publisher
Koh B, Hufford M, Sun X, Kaplan M. Etv5 Regulates IL-10 Production in Th Cells. J Immunol. 2017;198:2165-2171 pubmed publisher
Goodman C, Sato T, Peck A, Girondo M, Yang N, Liu C, et al. Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism. Oncogene. 2016;35:1373-85 pubmed publisher
Weissferdt A, Kalhor N, Liu H, Rodriguez J, Fujimoto J, Tang X, et al. Thymic neuroendocrine tumors (paraganglioma and carcinoid tumors): a comparative immunohistochemical study of 46 cases. Hum Pathol. 2014;45:2463-70 pubmed publisher
Malu D, Bélanger B, Desautels F, Kelendji K, Dalko E, Sanchez Dardon J, et al. Macrophage migration inhibitory factor: a downregulator of early T cell-dependent IFN-gamma responses in Plasmodium chabaudi adami (556 KA)-infected mice. J Immunol. 2011;186:6271-9 pubmed publisher
product information
SKU :
5852P
Product-Name :
GATA-3 (D13C9) XP® Rabbit mAb
Size :
40 ul
Price-(USD) :
135 USD
Species-x-Reactivity :
H, (Mk)
Applications :
Flow cytometry
Product-Category :
Developmental Biology
Shipping-Temp :
COLD
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
48
Host :
Rabbit
Target :
GATA3
Primary-Protein :
GATA3
Alt-Names :
GATA binding protein 3,GATA-binding factor 3,GATA3,HDR,MGC2346,MGC5199,MGC5445,Trans-acting T-cell-specific transcription factor GATA-3
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
https://www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.