product summary
company name :
Cell Signaling Technology
product type :
antibody
product name :
Brd2 (D89B4) Rabbit mAb
catalog :
5848S
quantity :
100 ul
price :
235 USD
clonality :
monoclonal
host :
rabbit
clone name :
D89B4

The same clone is also sold as:
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, chromatin immunoprecipitation, ChIP-Seq
more info or order :
Cell Signaling Technology product webpage
citations: 7
Published Application/Species/DilutionReference
  • western blot (knockdown validation); human; 1:500; fig 6
Werner A, Iwasaki S, McGourty C, Medina-Ruíz S, Teerikorpi N, Fedrigo I, et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015;525:523-7 pubmed publisher
  • western blot; human; 1:1000; fig 3h
Shao Z, Zhang R, Khodadadi-Jamayran A, Chen B, Crowley M, Festok M, et al. The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis. Nat Commun. 2016;7:10869 pubmed publisher
  • western blot; human; fig 2
Raina K, Lu J, Qian Y, Altieri M, Gordon D, Rossi A, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016;113:7124-9 pubmed publisher
  • immunohistochemistry; human; 1:100; fig s2
Tögel L, Nightingale R, Chueh A, Jayachandran A, Tran H, Phesse T, et al. Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells. Mol Cancer Ther. 2016;15:1217-26 pubmed publisher
  • chromatin immunoprecipitation; human; fig 8
Chan S, Selth L, Li Y, Nyquist M, Miao L, Bradner J, et al. Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies. Nucleic Acids Res. 2015;43:5880-97 pubmed publisher
  • western blot; mouse; 1:1000; fig 1a
Mazur P, Herner A, Mello S, Wirth M, Hausmann S, Sanchez-Rivera F, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nat Med. 2015;21:1163-71 pubmed publisher
  • ChIP-Seq; human
Anders L, Guenther M, Qi J, Fan Z, Marineau J, Rahl P, et al. Genome-wide localization of small molecules. Nat Biotechnol. 2014;32:92-6 pubmed publisher
product information
SKU :
5848S
Product-Name :
Brd2 (D89B4) Rabbit mAb
Size :
100 ul
Price-(USD) :
235 USD
Species-x-Reactivity :
H, M, (R, Mk)
Applications :
Western blot
Product-Category :
Chromatin Regulation / Nuclear Function
Shipping-Temp :
AMBIENT
Storage-Temp :
-20°C
Product-Type :
Monoclonal Antibody
MW :
110
Host :
Rabbit
Target :
BRD2
Primary-Protein :
BRD2
Alt-Names :
BRD2,Bromodomain-containing protein 2,D6S113E,DKFZp686N0336,FLJ31942,FSH,FSRG1,KIAA9001,NAT,O27.1.1,RING3,RNF3,Really interesting new gene 3 protein,bromodomain containing 2,bromodomain-containing 2,female sterile homeotic-related gene 1
more info or order :
Cell Signaling Technology product webpage
company information
Cell Signaling Technology
3 Trask Lane
Danvers, MA 01923
info@cellsignal.com
www.cellsignal.com
8776162355
headquarters: USA
Established in Beverly, MA in 1999, Cell Signaling Technology (CST) is a privately-owned company with over 400 employees worldwide. We are dedicated to providing innovative research tools that are used to help define mechanisms underlying cell function and disease. Since its inception, CST has become the world leader in the production of the highest quality activation-state and total protein antibodies utilized to expand knowledge of cell signaling pathways. Our mission is to deliver the world's highest quality research tools that accelerate progress in biological research and personalized medicine.