Brd2 (D89B4) Rabbit mAb | Cell Signaling Technology 5848 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

Brd2 (D89B4) Rabbit mAb

catalog :

5848

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D89B4

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, chromatin immunoprecipitation, ChIP-Seq

more info or order :

Cell Signaling Technology product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig s5b	Tyler D, Vappiani J, CaÃ±eque T, Lam E, Ward A, Gilan O, et al. Click chemistry enables preclinical evaluation of targeted epigenetic therapies. Science. 2017;356:1397-1401 pubmed publisher
western blot; human; loading ...; fig s3d	Sherman M, Yu R, Tseng T, Sousa C, Liu S, Truitt M, et al. Stromal cues regulate the pancreatic cancer epigenome and metabolome. Proc Natl Acad Sci U S A. 2017;114:1129-1134 pubmed publisher
western blot; human; fig 2	Raina K, Lu J, Qian Y, Altieri M, Gordon D, Rossi A, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016;113:7124-9 pubmed publisher
immunohistochemistry; human; 1:100; fig s2	TÃ¶gel L, Nightingale R, Chueh A, Jayachandran A, Tran H, Phesse T, et al. Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells. Mol Cancer Ther. 2016;15:1217-26 pubmed publisher
western blot; human; 1:1000; fig 3h	Shao Z, Zhang R, Khodadadi Jamayran A, Chen B, Crowley M, Festok M, et al. The acetyllysine reader BRD3R promotes human nuclear reprogramming and regulates mitosis. Nat Commun. 2016;7:10869 pubmed publisher
western blot; human; 1:500; fig 6	Werner A, Iwasaki S, McGourty C, Medina Ruiz S, Teerikorpi N, Fedrigo I, et al. Cell-fate determination by ubiquitin-dependent regulation of translation. Nature. 2015;525:523-7 pubmed publisher
western blot; mouse; 1:1000; fig 1a	Mazur P, Herner A, Mello S, Wirth M, Hausmann S, SÃ¡nchez Rivera F, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nat Med. 2015;21:1163-71 pubmed publisher
chromatin immunoprecipitation; human; fig 8	Chan S, Selth L, Li Y, Nyquist M, Miao L, Bradner J, et al. Targeting chromatin binding regulation of constitutively active AR variants to overcome prostate cancer resistance to endocrine-based therapies. Nucleic Acids Res. 2015;43:5880-97 pubmed publisher
ChIP-Seq; human	Anders L, Guenther M, Qi J, Fan Z, Marineau J, Rahl P, et al. Genome-wide localization of small molecules. Nat Biotechnol. 2014;32:92-6 pubmed publisher
	Sin Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, et al. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 2019;36:51-67.e7 pubmed publisher
	Vo B, Kwon J, Li C, Finkelstein D, Xu B, Orr B, et al. Mouse medulloblastoma driven by CRISPR activation of cellular Myc. Sci Rep. 2018;8:8733 pubmed publisher
	Hsu S, Gilgenast T, Bartman C, Edwards C, Stonestrom A, Huang P, et al. The BET Protein BRD2 Cooperates with CTCF to Enforce Transcriptional and Architectural Boundaries. Mol Cell. 2017;66:102-116.e7 pubmed publisher
	Lai X, Wang M, McElyea S, Sherman S, House M, Korc M. A microRNA signature in circulating exosomes is superior to exosomal glypican-1 levels for diagnosing pancreatic cancer. Cancer Lett. 2017;393:86-93 pubmed publisher

product information

SKU :

5848S

Product-Name :

Brd2 (D89B4) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

H, M, (R, Mk)

Applications :

Western blot

Product-Category :

Chromatin Regulation / Nuclear Function

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

110

Host :

Rabbit

Target :

BRD2

Primary-Protein :

BRD2

Alt-Names :

BRD2,Bromodomain-containing protein 2,D6S113E,DKFZp686N0336,FLJ31942,FSH,FSRG1,KIAA9001,NAT,O27.1.1,RING3,RNF3,Really interesting new gene 3 protein,bromodomain containing 2,bromodomain-containing 2,female sterile homeotic-related gene 1

more info or order :

Cell Signaling Technology product webpage