| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; mouse; loading ...; fig 4c
| Moya I, Castaldo S, Van den Mooter L, Soheily S, Sansores Garcia L, Jacobs J, et al. Peritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice. Science. 2019;366:1029-1034 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1s2c
| Jewell J, Fu V, Hong A, Yu F, Meng D, Melick C, et al. GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. elife. 2019;8: pubmed publisher |
- western blot; human; loading ...; fig 3f
| Xu D, Li X, Shao F, Lv G, Lv H, Lee J, et al. The protein kinase activity of fructokinase A specifies the antioxidant responses of tumor cells by phosphorylating p62. Sci Adv. 2019;5:eaav4570 pubmed publisher |
- western blot; brown rat; 1:1000; loading ...; fig 3b, 4f, 5f
| Zhou X, Zhang R, Zou Z, Shen X, Xie T, Xu C, et al. Hypoglycaemic effects of glimepiride in sulfonylurea receptor 1 deficient rat. Br J Pharmacol. 2019;176:478-490 pubmed publisher |
- immunoprecipitation; human; 1:200; loading ...; fig 2b
- western blot; human; 1:2000; loading ...; fig 1h
| Cha J, Yang W, Xia W, Wei Y, Chan L, Lim S, et al. Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1. Mol Cell. 2018;71:606-620.e7 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 8b
| Piragyte I, Clapes T, Polyzou A, Klein Geltink R, Lefkopoulos S, Yin N, et al. A metabolic interplay coordinated by HLX regulates myeloid differentiation and AML through partly overlapping pathways. Nat Commun. 2018;9:3090 pubmed publisher |
- immunoprecipitation; mouse; fig 7g
- western blot; mouse; 1:1000; loading ...; fig 7g, 7a
| Zhu L, Xie X, Zhang L, Wang H, Jie Z, Zhou X, et al. TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival. Nat Commun. 2018;9:2812 pubmed publisher |
- western blot; human; loading ...; fig s2
| Reuther C, Heinzle V, Nölting S, Herterich S, Hahner S, Halilovic E, et al. The HDM2 (MDM2) Inhibitor NVP-CGM097 Inhibits Tumor Cell Proliferation and Shows Additive Effects with 5-Fluorouracil on the p53-p21-Rb-E2F1 Cascade in the p53wild type Neuroendocrine Tumor Cell Line GOT1. Neuroendocrinology. 2018;106:1-19 pubmed publisher |
- western blot; human; loading ...; fig 1b
| Li X, Yu W, Qian X, Xia Y, Zheng Y, Lee J, et al. Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy. Mol Cell. 2017;66:684-697.e9 pubmed publisher |
- western blot; mouse; loading ...; fig 2b2
| Prasad S, Sajja R, Kaisar M, Park J, Villalba H, Liles T, et al. Role of Nrf2 and protective effects of Metformin against tobacco smoke-induced cerebrovascular toxicity. Redox Biol. 2017;12:58-69 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 6c
| Hogarth M, Houweling P, Thomas K, Gordish Dressman H, Bello L, Pegoraro E, et al. Evidence for ACTN3 as a genetic modifier of Duchenne muscular dystrophy. Nat Commun. 2017;8:14143 pubmed publisher |
- western blot; human; loading ...; fig s4a
| Dey P, Baddour J, Muller F, Wu C, Wang H, Liao W, et al. Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer. Nature. 2017;542:119-123 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig s5d
| Calamita P, Miluzio A, Russo A, Pesce E, Ricciardi S, Khanim F, et al. SBDS-Deficient Cells Have an Altered Homeostatic Equilibrium due to Translational Inefficiency Which Explains their Reduced Fitness and Provides a Logical Framework for Intervention. PLoS Genet. 2017;13:e1006552 pubmed publisher |
- western blot; mouse; loading ...; fig s20
| Conlon D, Thomas T, Fedotova T, Hernandez Ono A, Di Paolo G, Chan R, et al. Inhibition of apolipoprotein B synthesis stimulates endoplasmic reticulum autophagy that prevents steatosis. J Clin Invest. 2016;126:3852-3867 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 5d
| Liu J, Liang X, Zhou D, Lai L, Xiao L, Liu L, et al. Coupling of mitochondrial function and skeletal muscle fiber type by a miR-499/Fnip1/AMPK circuit. EMBO Mol Med. 2016;8:1212-1228 pubmed publisher |
- western blot; mouse; fig s2
| Song J, Sun Y, Peluso I, Zeng Y, Yu X, Lu J, et al. A novel curcumin analog binds to and activates TFEB in vitro and in vivo independent of MTOR inhibition. Autophagy. 2016;12:1372-89 pubmed publisher |
- immunocytochemistry; human; 1:100; fig 3
| Schmitt D, Cheng Y, Park J, An S. Sequestration-Mediated Downregulation of de Novo Purine Biosynthesis by AMPK. ACS Chem Biol. 2016;11:1917-24 pubmed publisher |
- western blot; mouse; 1:1000; fig 5
| Cui J, Zhang F, Wang Y, Liu J, Ming X, Hou J, et al. Macrophage migration inhibitory factor promotes cardiac stem cell proliferation and endothelial differentiation through the activation of the PI3K/Akt/mTOR and AMPK pathways. Int J Mol Med. 2016;37:1299-309 pubmed publisher |
- western blot; human; loading ...; fig 2a
| Douglas D, Pu C, Lewis J, Bhat R, Anwar Mohamed A, Logan M, et al. Oxidative Stress Attenuates Lipid Synthesis and Increases Mitochondrial Fatty Acid Oxidation in Hepatoma Cells Infected with Hepatitis C Virus. J Biol Chem. 2016;291:1974-90 pubmed publisher |
- western blot; swine; fig 10
| Ledee D, Kajimoto M, O Kelly Priddy C, Olson A, Isern N, Robillard Frayne I, et al. Pyruvate modifies metabolic flux and nutrient sensing during extracorporeal membrane oxygenation in an immature swine model. Am J Physiol Heart Circ Physiol. 2015;309:H137-46 pubmed publisher |
- western blot; human; fig 6
| Xie Q, Wu Q, Horbinski C, Flavahan W, Yang K, Zhou W, et al. Mitochondrial control by DRP1 in brain tumor initiating cells. Nat Neurosci. 2015;18:501-10 pubmed publisher |
| Zhuo X, Wu Y, Ni Y, Liu J, Gong M, Wang X, et al. Isoproterenol instigates cardiomyocyte apoptosis and heart failure via AMPK inactivation-mediated endoplasmic reticulum stress. Apoptosis. 2013;18:800-10 pubmed publisher |
| Elf S, Lin R, Xia S, Pan Y, Shan C, Wu S, et al. Targeting 6-phosphogluconate dehydrogenase in the oxidative PPP sensitizes leukemia cells to antimalarial agent dihydroartemisinin. Oncogene. 2017;36:254-262 pubmed publisher |
| Chen Y, Lv L, Pi H, Qin W, Chen J, Guo D, et al. Dihydromyricetin protects against liver ischemia/reperfusion induced apoptosis via activation of FOXO3a-mediated autophagy. Oncotarget. 2016;7:76508-76522 pubmed publisher |
| Ban H, Xu X, Jang K, Kim I, Kim B, Lee K, et al. A Novel Malate Dehydrogenase 2 Inhibitor Suppresses Hypoxia-Inducible Factor-1 by Regulating Mitochondrial Respiration. PLoS ONE. 2016;11:e0162568 pubmed publisher |
| Hou L, Li Y, Song H, Zhang Z, Sun Y, Zhang X, et al. Protective Macroautophagy Is Involved in Vitamin E Succinate Effects on Human Gastric Carcinoma Cell Line SGC-7901 by Inhibiting mTOR Axis Phosphorylation. PLoS ONE. 2015;10:e0132829 pubmed publisher |
| Wu X, He L, Chen F, He X, Cai Y, Zhang G, et al. Impaired autophagy contributes to adverse cardiac remodeling in acute myocardial infarction. PLoS ONE. 2014;9:e112891 pubmed publisher |
| Kumar D, Shankar S, Srivastava R. Rottlerin induces autophagy and apoptosis in prostate cancer stem cells via PI3K/Akt/mTOR signaling pathway. Cancer Lett. 2014;343:179-89 pubmed publisher |
