| Published Application/Species/Dilution | Reference |
|---|
- immunohistochemistry - paraffin section; mouse; 1:50; fig 3
| Majumder K, Arora N, Modi S, Chugh R, Nomura A, Giri B, et al. A Novel Immunocompetent Mouse Model of Pancreatic Cancer with Robust Stroma: a Valuable Tool for Preclinical Evaluation of New Therapies. J Gastrointest Surg. 2016;20:53-65 pubmed publisher |
- western blot; human; fig 3a
- immunocytochemistry; human; fig 3c
| Yokdang N, Hatakeyama J, Wald J, Simion C, Tellez J, Chang D, et al. LRIG1 opposes epithelial-to-mesenchymal transition and inhibits invasion of basal-like breast cancer cells. Oncogene. 2016;35:2932-47 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; fig 5
- western blot; mouse; fig 5
| Ren S, Luo Y, Chen H, Warburton D, Lam H, Wang L, et al. Inactivation of Tsc2 in Mesoderm-Derived Cells Causes Polycystic Kidney Lesions and Impairs Lung Alveolarization. Am J Pathol. 2016;186:3261-3272 pubmed publisher |
- western blot; human; fig 4
| Qi Y, Yu J, Han W, Fan X, Qian H, Wei H, et al. A splicing isoform of TEAD4 attenuates the Hippo-YAP signalling to inhibit tumour proliferation. Nat Commun. 2016;7:ncomms11840 pubmed publisher |
- western blot; human; fig 4
| Debruyne D, Bhatnagar N, Sharma B, Luther W, Moore N, Cheung N, et al. ALK inhibitor resistance in ALK(F1174L)-driven neuroblastoma is associated with AXL activation and induction of EMT. Oncogene. 2016;35:3681-91 pubmed publisher |
- western blot; human; fig 5
| Chen X, Stauffer S, Chen Y, Dong J. Ajuba Phosphorylation by CDK1 Promotes Cell Proliferation and Tumorigenesis. J Biol Chem. 2016;: pubmed |
- immunocytochemistry; human; 1:100; fig 5
- western blot; human; 1:100; fig 5
| Tan X, Fu Y, Chen L, Lee W, Lai Y, Rezaei K, et al. miR-671-5p inhibits epithelial-to-mesenchymal transition by downregulating FOXM1 expression in breast cancer. Oncotarget. 2016;7:293-307 pubmed publisher |
- western blot; human; 1:1000; fig 2
| Dhar S, Kumar A, Zhang L, Rimando A, Lage J, Lewin J, et al. Dietary pterostilbene is a novel MTA1-targeted chemopreventive and therapeutic agent in prostate cancer. Oncotarget. 2016;7:18469-84 pubmed publisher |
- western blot; human; 1:1000; fig s8
| Chung I, Reichelt M, Shao L, Akita R, Koeppen H, Rangell L, et al. High cell-surface density of HER2 deforms cell membranes. Nat Commun. 2016;7:12742 pubmed publisher |
- western blot; human; fig 3b
| Guo Y, Wang L, Li B, Xu H, Yang J, Zheng L, et al. Wnt/β-catenin pathway transactivates microRNA-150 that promotes EMT of colorectal cancer cells by suppressing CREB signaling. Oncotarget. 2016;: pubmed publisher |
- immunocytochemistry; mouse; fig 5
| Sun H, Chen J, Qian W, Kang J, Wang J, Jiang L, et al. Integrated long non-coding RNA analyses identify novel regulators of epithelial-mesenchymal transition in the mouse model of pulmonary fibrosis. J Cell Mol Med. 2016;20:1234-46 pubmed publisher |
- western blot; human; 1:1000; fig 1
| Bassey-Archibong B, Kwiecien J, Milosavljevic S, Hallett R, Rayner L, Erb M, et al. Kaiso depletion attenuates transforming growth factor-β signaling and metastatic activity of triple-negative breast cancer cells. Oncogenesis. 2016;5:e208 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; fig 4
| Creedon H, Balderstone L, Muir M, Balla J, Gómez-Cuadrado L, Tracey N, et al. Use of a genetically engineered mouse model as a preclinical tool for HER2 breast cancer. Dis Model Mech. 2016;9:131-40 pubmed publisher |
- western blot; human; fig 6
| Wang F, Feng Y, Li P, Wang K, Feng L, Liu Y, et al. RASSF10 is an epigenetically inactivated tumor suppressor and independent prognostic factor in hepatocellular carcinoma. Oncotarget. 2016;7:4279-97 pubmed publisher |
- immunocytochemistry; human; 1:200; fig 5
| Toneff M, Sreekumar A, Tinnirello A, Hollander P, Habib S, Li S, et al. The Z-cad dual fluorescent sensor detects dynamic changes between the epithelial and mesenchymal cellular states. BMC Biol. 2016;14:47 pubmed publisher |
- western blot; mouse; fig 3
| Palla A, Piazzolla D, Alcazar N, Canamero M, Grana O, Gomez-Lopez G, et al. The pluripotency factor NANOG promotes the formation of squamous cell carcinomas. Sci Rep. 2015;5:10205 pubmed publisher |
- western blot; human
- immunocytochemistry; human; 1:200
| Costabile V, Duraturo F, Delrio P, Rega D, Pace U, Liccardo R, et al. Lithium chloride induces mesenchymal‑to‑epithelial reverting transition in primary colon cancer cell cultures. Int J Oncol. 2015;46:1913-23 pubmed publisher |
- immunohistochemistry; human; fig 5
| Gong X, Yi J, Carmon K, Crumbley C, Xiong W, Thomas A, et al. Aberrant RSPO3-LGR4 signaling in Keap1-deficient lung adenocarcinomas promotes tumor aggressiveness. Oncogene. 2015;34:4692-701 pubmed publisher |
- western blot; human; 1:1000; fig 4
| Wang H, Bao W, Jiang F, Che Q, Chen Z, Wang F, et al. Mutant p53 (p53-R248Q) functions as an oncogene in promoting endometrial cancer by up-regulating REGγ. Cancer Lett. 2015;360:269-79 pubmed publisher |
- western blot; human; fig 1
| Zhang Y, Wei X, Liang Y, Chen W, Zhang F, Bai J, et al. Over-Expressed Twist Associates with Markers of Epithelial Mesenchymal Transition and Predicts Poor Prognosis in Breast Cancers via ERK and Akt Activation. PLoS ONE. 2015;10:e0135851 pubmed publisher |
- western blot; mouse; 1:3000; fig 5
| Sato M, Matsubara T, Adachi J, Hashimoto Y, Fukamizu K, Kishida M, et al. Differential Proteome Analysis Identifies TGF-β-Related Pro-Metastatic Proteins in a 4T1 Murine Breast Cancer Model. PLoS ONE. 2015;10:e0126483 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
| Knezevic J, Pfefferle A, Petrovic I, Greene S, Perou C, Rosen J. Expression of miR-200c in claudin-low breast cancer alters stem cell functionality, enhances chemosensitivity and reduces metastatic potential. Oncogene. 2015;34:5997-6006 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:100; fig 2
| Kessler M, Hoffmann K, Brinkmann V, Thieck O, Jackisch S, Toelle B, et al. The Notch and Wnt pathways regulate stemness and differentiation in human fallopian tube organoids. Nat Commun. 2015;6:8989 pubmed publisher |
| Shriver M, Stroka K, Vitolo M, Martin S, Huso D, Konstantopoulos K, et al. Loss of giant obscurins from breast epithelium promotes epithelial-to-mesenchymal transition, tumorigenicity and metastasis. Oncogene. 2015;34:4248-59 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:50; fig 6
- western blot; mouse; 1:1000; fig 6
| Lin X, Xu W, Shao M, Fan Q, Wen G, Li C, et al. Shenling Baizhu San supresses colitis associated colorectal cancer through inhibition of epithelial-mesenchymal transition and myeloid-derived suppressor infiltration. BMC Complement Altern Med. 2015;15:126 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:600; fig 4
| Dubois V, Simitsidellis I, Laurent M, Jardí F, Saunders P, Vanderschueren D, et al. Enobosarm (GTx-024) Modulates Adult Skeletal Muscle Mass Independently of the Androgen Receptor in the Satellite Cell Lineage. Endocrinology. 2015;156:4522-33 pubmed publisher |
- western blot; mouse; 1:1000; fig 6
| Maris P, Blomme A, Palacios A, Costanza B, Bellahcene A, Bianchi E, et al. Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer. PLoS Med. 2015;12:e1001871 pubmed publisher |
- immunocytochemistry; human
- western blot; human
| Soncini D, Caffa I, Zoppoli G, Cea M, Cagnetta A, Passalacqua M, et al. Nicotinamide phosphoribosyltransferase promotes epithelial-to-mesenchymal transition as a soluble factor independent of its enzymatic activity. J Biol Chem. 2014;289:34189-204 pubmed publisher |
- immunohistochemistry - paraffin section; mouse; 1:200
| Gao Y, Bayless K, Li Q. TGFBR1 is required for mouse myometrial development. Mol Endocrinol. 2014;28:380-94 pubmed publisher |
| Lu G, Zhang Q, Huang Y, Song J, Tomaino R, Ehrenberger T, et al. Phosphorylation of ETS1 by Src family kinases prevents its recognition by the COP1 tumor suppressor. Cancer Cell. 2014;26:222-34 pubmed publisher |
| Bao Y, Cao X, Luo D, Sun R, Peng L, Wang L, et al. Urokinase-type plasminogen activator receptor signaling is critical in nasopharyngeal carcinoma cell growth and metastasis. Cell Cycle. 2014;13:1958-69 pubmed publisher |
| Ulanet D, Couto K, Jha A, Choe S, Wang A, Woo H, et al. Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition. PLoS ONE. 2014;9:e115144 pubmed publisher |
| Yoshida T, Ozawa Y, Kimura T, Sato Y, Kuznetsov G, Xu S, et al. Eribulin mesilate suppresses experimental metastasis of breast cancer cells by reversing phenotype from epithelial-mesenchymal transition (EMT) to mesenchymal-epithelial transition (MET) states. Br J Cancer. 2014;110:1497-505 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
| Aoshiba K, Tsuji T, Itoh M, Semba S, Yamaguchi K, Nakamura H, et al. A murine model of airway fibrosis induced by repeated naphthalene exposure. Exp Toxicol Pathol. 2014;66:169-77 pubmed publisher |
- western blot; human; 1:500
| Liang W, Hao Z, Han J, Zhu D, Jin Z, Xie W. CAV-1 contributes to bladder cancer progression by inducing epithelial-to-mesenchymal transition. Urol Oncol. 2014;32:855-63 pubmed publisher |
| Subramani R, Lopez-Valdez R, Arumugam A, Nandy S, Boopalan T, Lakshmanaswamy R. Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. PLoS ONE. 2014;9:e97016 pubmed publisher |
- immunohistochemistry - paraffin section; human; 1:600
| Greaves E, Cousins F, Murray A, Esnal-Zufiaurre A, Fassbender A, Horne A, et al. A novel mouse model of endometriosis mimics human phenotype and reveals insights into the inflammatory contribution of shed endometrium. Am J Pathol. 2014;184:1930-9 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
| Aoshiba K, Tsuji T, Kameyama S, Itoh M, Semba S, Yamaguchi K, et al. Senescence-associated secretory phenotype in a mouse model of bleomycin-induced lung injury. Exp Toxicol Pathol. 2013;65:1053-62 pubmed publisher |
- immunohistochemistry - paraffin section; mouse
| Park J, Morley T, Scherer P. Inhibition of endotrophin, a cleavage product of collagen VI, confers cisplatin sensitivity to tumours. EMBO Mol Med. 2013;5:935-48 pubmed publisher |
- western blot; human; 1:500
| Peng Y, Shi Y, Ding Z, Ke A, Gu C, Hui B, et al. Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells. Autophagy. 2013;9:2056-68 pubmed publisher |
| Ford C, Jary E, Ma S, Nixdorf S, Heinzelmann-Schwarz V, Ward R. The Wnt gatekeeper SFRP4 modulates EMT, cell migration and downstream Wnt signalling in serous ovarian cancer cells. PLoS ONE. 2013;8:e54362 pubmed publisher |
| Chang L, Li C, Lan T, Wu L, Yuan Y, Liu Q, et al. Decreased expression of long non-coding RNA GAS5 indicates a poor prognosis and promotes cell proliferation and invasion in hepatocellular carcinoma by regulating vimentin. Mol Med Rep. 2016;13:1541-50 pubmed publisher |
| Liu H, Wu Y, Zhu S, Liang W, Wang Z, Wang Y, et al. PTP1B promotes cell proliferation and metastasis through activating src and ERK1/2 in non-small cell lung cancer. Cancer Lett. 2015;359:218-25 pubmed publisher |
| Park H, Bolton E. Glial cell line-derived neurotrophic factor induces cell proliferation in the mouse urogenital sinus. Mol Endocrinol. 2015;29:289-306 pubmed publisher |
| He F, Li J, Xu J, Zhang S, Xu Y, Zhao W, et al. Decreased expression of ARID1A associates with poor prognosis and promotes metastases of hepatocellular carcinoma. J Exp Clin Cancer Res. 2015;34:47 pubmed publisher |
| Couderc C, Bollard J, Coute Y, Massoma P, Poncet G, Lepinasse F, et al. Mechanisms of local invasion in enteroendocrine tumors: identification of novel candidate cytoskeleton-associated proteins in an experimental mouse model by a proteomic approach and validation in human tumors. Mol Cell Endocrinol. 2015;399:154-63 pubmed publisher |
| Lin X, Yi Z, Diao J, Shao M, Zhao L, Cai H, et al. ShaoYao decoction ameliorates colitis-associated colorectal cancer by downregulating proinflammatory cytokines and promoting epithelial-mesenchymal transition. J Transl Med. 2014;12:105 pubmed publisher |
| Han Y, Ye J, Wu D, Wu P, Chen Z, Chen J, et al. LEIGC long non-coding RNA acts as a tumor suppressor in gastric carcinoma by inhibiting the epithelial-to-mesenchymal transition. BMC Cancer. 2014;14:932 pubmed publisher |
| Colin S, Darne B, Kadi A, Ferry A, Favier M, Lesaffre C, et al. The antiangiogenic insulin receptor substrate-1 antisense oligonucleotide aganirsen impairs AU-rich mRNA stability by reducing 14-3-3β-tristetraprolin protein complex, reducing inflammation and psoriatic lesion size in patients. J Pharmacol Exp Ther. 2014;349:107-17 pubmed publisher |
| Voll E, Ogden I, Pavese J, Huang X, Xu L, Jovanovic B, et al. Heat shock protein 27 regulates human prostate cancer cell motility and metastatic progression. Oncotarget. 2014;5:2648-63 pubmed |
| Mele V, Muraro M, Calabrese D, Pfaff D, Amatruda N, Amicarella F, et al. Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-β. Int J Cancer. 2014;134:2583-94 pubmed publisher |
| Su P, Hu J, Zhang H, Li W, Jia M, Zhang X, et al. IMP3 expression is associated with epithelial-mesenchymal transition in breast cancer. Int J Clin Exp Pathol. 2014;7:3008-17 pubmed |
| Lu J, Lee W, Kim M, Yun J, Jung J, Yi S, et al. The inhibitory effect of anthocyanins on Akt on invasion and epithelial-mesenchymal transition is not associated with the anti-EGFR effect of the anthocyanins. Int J Oncol. 2014;44:1756-66 pubmed publisher |
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| Matsuyama M, Tanaka H, Inoko A, Goto H, Yonemura S, Kobori K, et al. Defect of mitotic vimentin phosphorylation causes microophthalmia and cataract via aneuploidy and senescence in lens epithelial cells. J Biol Chem. 2013;288:35626-35 pubmed publisher |
| Wu X, Xi X, Yan Q, Zhang Z, Cai B, Lu W, et al. MicroRNA-361-5p facilitates cervical cancer progression through mediation of epithelial-to-mesenchymal transition. Med Oncol. 2013;30:751 pubmed publisher |
| Hagemann J, Thomasova D, Mulay S, Anders H. Nrf2 signalling promotes ex vivo tubular epithelial cell survival and regeneration via murine double minute (MDM)-2. Nephrol Dial Transplant. 2013;28:2028-37 pubmed publisher |
| Zhou D, Tan R, Zhou L, Li Y, Liu Y. Kidney tubular β-catenin signaling controls interstitial fibroblast fate via epithelial-mesenchymal communication. Sci Rep. 2013;3:1878 pubmed publisher |
| Guo M, Wang M, Deng H, Zhang X, Wang Z. A novel anticancer agent Broussoflavonol B downregulates estrogen receptor (ER)-α36 expression and inhibits growth of ER-negative breast cancer MDA-MB-231 cells. Eur J Pharmacol. 2013;714:56-64 pubmed publisher |
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| Wang Q, Wang H, Zhang Y, Zhang Y, Xiao W. Activation of uPAR is required for cigarette smoke extract-induced epithelial-mesenchymal transition in lung epithelial cells. Oncol Res. 2013;21:295-305 pubmed publisher |
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