RING1B (D22F2) XP® Rabbit mAb | Cell Signaling Technology 5694 product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

RING1B (D22F2) XP® Rabbit mAb

catalog :

5694

clonality :

monoclonal

host :

domestic rabbit

conjugate :

nonconjugated

clone name :

D22F2

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, immunohistochemistry - frozen section, ChIP-Seq

more info or order :

Cell Signaling Technology product webpage

citations: 18

Published Application/Species/Sample/Dilution	Reference
ChIP-Seq; mouse; 1:1000; loading ...	Rhodes J, Feldmann A, Hernández Rodríguez B, Díaz N, Brown J, Fursova N, et al. Cohesin Disrupts Polycomb-Dependent Chromosome Interactions in Embryonic Stem Cells. Cell Rep. 2020;30:820-835.e10 pubmed publisher
ChIP-Seq; mouse; loading ...; fig 1f	Fursova N, Blackledge N, Nakayama M, Ito S, Koseki Y, Farcas A, et al. Synergy between Variant PRC1 Complexes Defines Polycomb-Mediated Gene Repression. Mol Cell. 2019;74:1020-1036.e8 pubmed publisher
western blot; mouse; loading ...; fig s2i	He M, Chaurushiya M, Webster J, Kummerfeld S, Reja R, Chaudhuri S, et al. Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1. Science. 2019;364:283-285 pubmed publisher
western blot; mouse; loading ...; fig 1g	Nishioka K, Miyazaki H, Soejima H. Unbiased shRNA screening, using a combination of FACS and high-throughput sequencing, enables identification of novel modifiers of Polycomb silencing. Sci Rep. 2018;8:12128 pubmed publisher
immunocytochemistry; human; 1:1000; loading ...; fig 4d western blot; human; 1:1000; loading ...; fig 7a	Patel N, Garikapati K, Pandita R, Singh D, Pandita T, Bhadra U, et al. miR-15a/miR-16 down-regulates BMI1, impacting Ub-H2A mediated DNA repair and breast cancer cell sensitivity to doxorubicin. Sci Rep. 2017;7:4263 pubmed publisher
immunoprecipitation; human; loading ...; fig 1c western blot; human; loading ...; fig 1d	Wheaton K, Sarkari F, Stanly Johns B, Davarinejad H, Egorova O, Kaustov L, et al. UbE2E1/UBCH6 Is a Critical in Vivo E2 for the PRC1-catalyzed Ubiquitination of H2A at Lys-119. J Biol Chem. 2017;292:2893-2902 pubmed publisher
western blot; human; loading ...; fig 1e	Fang D, Gan H, Lee J, Han J, Wang Z, Riester S, et al. The histone H3.3K36M mutation reprograms the epigenome of chondroblastomas. Science. 2016;352:1344-8 pubmed publisher
immunohistochemistry - frozen section; mouse; 1:1000; fig s2	Mardaryev A, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, et al. Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016;212:77-89 pubmed publisher
chromatin immunoprecipitation; rat	Koo J, Mazei Robison M, LaPlant Q, Egervári G, Braunscheidel K, Adank D, et al. Epigenetic basis of opiate suppression of Bdnf gene expression in the ventral tegmental area. Nat Neurosci. 2015;18:415-22 pubmed publisher
chromatin immunoprecipitation; mouse	Lu F, Liu Y, Jiang L, Yamaguchi S, Zhang Y. Role of Tet proteins in enhancer activity and telomere elongation. Genes Dev. 2014;28:2103-19 pubmed publisher
chromatin immunoprecipitation; human immunoprecipitation; human	Cao Q, Wang X, Zhao M, Yang R, Malik R, Qiao Y, et al. The central role of EED in the orchestration of polycomb group complexes. Nat Commun. 2014;5:3127 pubmed publisher
	Blackledge N, Fursova N, Kelley J, Huseyin M, Feldmann A, Klose R. PRC1 Catalytic Activity Is Central to Polycomb System Function. Mol Cell. 2019;: pubmed publisher
	Lamb K, Bsteh D, Dishman S, Moussa H, Fan H, Stuckey J, et al. Discovery and Characterization of a Cellular Potent Positive Allosteric Modulator of the Polycomb Repressive Complex 1 Chromodomain, CBX7. Cell Chem Biol. 2019;26:1365-1379.e22 pubmed publisher
	Chitale S, Richly H. DICER- and MMSET-catalyzed H4K20me2 recruits the nucleotide excision repair factor XPA to DNA damage sites. J Cell Biol. 2018;217:527-540 pubmed publisher
	Chitale S, Richly H. DICER and ZRF1 contribute to chromatin decondensation during nucleotide excision repair. Nucleic Acids Res. 2017;45:5901-5912 pubmed publisher
	Benitz S, Regel I, Reinhard T, Popp A, SchÃ¤ffer I, Raulefs S, et al. Polycomb repressor complex 1 promotes gene silencing through H2AK119 mono-ubiquitination in acinar-to-ductal metaplasia and pancreatic cancer cells. Oncotarget. 2016;7:11424-33 pubmed publisher
	Inagaki T, Iwasaki S, Matsumura Y, Kawamura T, Tanaka T, Abe Y, et al. The FBXL10/KDM2B scaffolding protein associates with novel polycomb repressive complex-1 to regulate adipogenesis. J Biol Chem. 2015;290:4163-77 pubmed publisher
	Puvvula P, Desetty R, Pineau P, Marchio A, Moon A, Dejean A, et al. Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit. Nat Commun. 2014;5:5323 pubmed publisher

product information

SKU :

5694P

Product-Name :

RING1B (D22F2) XP® Rabbit mAb

Size :

40 ul

Price-(USD) :

135 USD

Species-x-Reactivity :

H, M, R, Mk

Applications :

Chromatin Immunoprecipitation

Product-Category :

Chromatin Regulation / Nuclear Function

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

Host :

Rabbit

Target :

RNF2

Primary-Protein :

RNF2

Alt-Names :

BAP-1,BAP1,DING,E3 ubiquitin-protein ligase RING2,HIP2-interacting protein 3,HIPI3,Huntingtin-interacting protein 2-interacting protein 3,Protein DinG,RING finger protein 1B,RING finger protein 2,RING finger protein BAP-1,RING1B,RING2,RNF2

more info or order :

Cell Signaling Technology product webpage