PERK (D11A8) Rabbit mAb | Cell Signaling Technology 5683S product information

product summary

company name :

Cell Signaling Technology

product type :

antibody

product name :

PERK (D11A8) Rabbit mAb

catalog :

5683S

quantity :

100 ul

price :

235 USD

clonality :

monoclonal

host :

rabbit

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Cell Signaling Technology product webpage

citations: 10

Published Application/Species/Dilution	Reference
western blot; mouse; 1:1000; fig 5	Plucińska K, Dekeryte R, Koss D, Shearer K, Mody N, Whitfield P, et al. Neuronal human BACE1 knockin induces systemic diabetes in mice. Diabetologia. 2016;59:1513-23 pubmed publisher
western blot; rat; fig 3	Hong M, Nam K, Kim K, Kim S, Kim I. The small molecule '1-(4-biphenylylcarbonyl)-4-(5-bromo-2-methoxybenzyl) piperazine oxalate' and its derivatives regulate global protein synthesis by inactivating eukaryotic translation initiation factor 2-alpha. Cell Stress Chaperones. 2016;21:485-97 pubmed publisher
western blot; human; 1:1000; fig s5	Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, et al. mTORC1 and CK2 coordinate ternary and eIF4F complex assembly. Nat Commun. 2016;7:11127 pubmed publisher
western blot; human; 1:1000; fig 7	Sakabe I, Hu R, Jin L, Clarke R, Kasid U. TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling. Breast Cancer Res Treat. 2015;153:285-97 pubmed publisher
western blot; human; 1:1000	Nagelkerke A, Sweep F, Stegeman H, Grenman R, Kaanders J, Bussink J, et al. Hypoxic regulation of the PERK/ATF4/LAMP3-arm of the unfolded protein response in head and neck squamous cell carcinoma. Head Neck. 2015;37:896-905 pubmed publisher
western blot; rat; 1:500; fig 1	Wong M, Nicholson C, Holloway A, Hardy D. Maternal nicotine exposure leads to impaired disulfide bond formation and augmented endoplasmic reticulum stress in the rat placenta. PLoS ONE. 2015;10:e0122295 pubmed publisher
western blot; mouse; 1:1000	Han J, Kaufman R. Measurement of the unfolded protein response to investigate its role in adipogenesis and obesity. Methods Enzymol. 2014;538:135-50 pubmed publisher
western blot; human; 1:500	Peng Y, Shi Y, Ding Z, Ke A, Gu C, Hui B, et al. Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells. Autophagy. 2013;9:2056-68 pubmed publisher
	Soderquist R, Danilov A, Eastman A. Gossypol increases expression of the pro-apoptotic BH3-only protein NOXA through a novel mechanism involving phospholipase A2, cytoplasmic calcium, and endoplasmic reticulum stress. J Biol Chem. 2014;289:16190-9 pubmed publisher
	Soderquist R, Pletnev A, Danilov A, Eastman A. The putative BH3 mimetic S1 sensitizes leukemia to ABT-737 by increasing reactive oxygen species, inducing endoplasmic reticulum stress, and upregulating the BH3-only protein NOXA. Apoptosis. 2014;19:201-9 pubmed publisher

product information

SKU :

5683S

Product-Name :

PERK (D11A8) Rabbit mAb

Size :

100 ul

Price-(USD) :

235 USD

Species-x-Reactivity :

Applications :

Immunohistochemistry (Paraffin)

Product-Category :

Protein Folding and Trafficking

Shipping-Temp :

AMBIENT

Storage-Temp :

-20°C

Product-Type :

Monoclonal Antibody

MW :

140

Host :

Rabbit

Target :

PERK

Primary-Protein :

PERK

Alt-Names :

DKFZp781H1925,E2AK3,EIF2AK3,Eukaryotic translation initiation factor 2-alpha kinase 3,HRI,HsPEK,PEK,PERK,PRKR-like endoplasmic reticulum kinase,Pancreatic eIF2-alpha kinase,WRS,eukaryotic translation initiation factor 2 alpha kinase 3,heme-regulated EIF2-alpha kinase

more info or order :

Cell Signaling Technology product webpage